ES278944A1 - Improvements in or relating to dibenzocyclohepta-diene and -triene derivatives - Google Patents
Improvements in or relating to dibenzocyclohepta-diene and -triene derivativesInfo
- Publication number
- ES278944A1 ES278944A1 ES0278944A ES278944A ES278944A1 ES 278944 A1 ES278944 A1 ES 278944A1 ES 0278944 A ES0278944 A ES 0278944A ES 278944 A ES278944 A ES 278944A ES 278944 A1 ES278944 A1 ES 278944A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- compound
- preparation
- compounds
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises: (a) compounds of the general formula <FORM:1012619/C2/1> (wherein R1 represents a hydrogen atom, R2 and R3 each represent a C1-4 alkyl radical, or R2 and R1, jointly represent an alkylene radical containing 2-4 carbon atoms in a straight chain, or R2 and R3 jointly form with the nitrogen atom a 5- or 6-membered heterocyclic ring which may contain an oxygen atom as the only other hetero-atom, and Z represents -CH = CH- or -CH2-CH2-) and their acid addition salts (b) the preparation of the compounds of (a) by dehydrating compounds of the general formula <FORM:1012619/C2/2> and, if desired, satisfying the product and/or, when Z is -CH = CH-, hydrogenating this to -CH2-CH2- (c) the combination of the process of (b) with the preparation of the starting material by reducing a compound of the general formula <FORM:1012619/C2/3> and (d) the combination of the process of (c) with the preparation of the starting material by condensing a compound of the general formula <FORM:1012619/C2/4> with a compound of the general formula R1-CH2-CO-NR2R3. Pharmaceutical compositions comprise bases of the first general formula above, or their pharmacologically acceptable acid addition salts, together with a pharmacologically acceptable inert carrier. They possess reserpine-, histamine-and serotonin-inhibiting and bronchodilatory activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH794061A CH402838A (en) | 1961-07-06 | 1961-07-06 | Process for the preparation of new basic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES278944A1 true ES278944A1 (en) | 1963-03-01 |
Family
ID=4332700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0278944A Expired ES278944A1 (en) | 1961-07-06 | 1962-07-05 | Improvements in or relating to dibenzocyclohepta-diene and -triene derivatives |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH402838A (en) |
| DK (1) | DK105918C (en) |
| ES (1) | ES278944A1 (en) |
| FR (1) | FR2093M (en) |
| GB (1) | GB1012619A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1543035A1 (en) * | 1965-01-06 | 1969-09-25 | Hoffmann La Roche | Process for the preparation of dibenzocycloheptene compounds |
-
1961
- 1961-07-06 CH CH794061A patent/CH402838A/en unknown
-
1962
- 1962-06-26 GB GB24452/62A patent/GB1012619A/en not_active Expired
- 1962-07-05 ES ES0278944A patent/ES278944A1/en not_active Expired
- 1962-07-05 DK DK300162A patent/DK105918C/en active
- 1962-10-01 FR FR910912A patent/FR2093M/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1012619A (en) | 1965-12-08 |
| CH402838A (en) | 1965-11-30 |
| FR2093M (en) | 1963-10-21 |
| DK105918C (en) | 1966-11-28 |
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