ES2788866T3 - Una composición farmacéutica que contiene ácido nicotínico y/o nicotinamida para su uso en influir beneficiosamente en los niveles de lípidos en sangre mediante la modificación de la microbiota intestinal - Google Patents
Una composición farmacéutica que contiene ácido nicotínico y/o nicotinamida para su uso en influir beneficiosamente en los niveles de lípidos en sangre mediante la modificación de la microbiota intestinal Download PDFInfo
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- ES2788866T3 ES2788866T3 ES14809908T ES14809908T ES2788866T3 ES 2788866 T3 ES2788866 T3 ES 2788866T3 ES 14809908 T ES14809908 T ES 14809908T ES 14809908 T ES14809908 T ES 14809908T ES 2788866 T3 ES2788866 T3 ES 2788866T3
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- nicotinamide
- blood
- pharmaceutical composition
- nicotinic acid
- plasma
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13197283 | 2013-12-13 | ||
| EP14154543 | 2014-02-10 | ||
| PCT/EP2014/077646 WO2015086843A2 (en) | 2013-12-13 | 2014-12-12 | A pharmaceutical composition containing nicotinic acid and/or nicotinamide for beneficially influencing blood lipid levels by modifying the intestinal microbiota |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2788866T3 true ES2788866T3 (es) | 2020-10-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14809908T Active ES2788866T3 (es) | 2013-12-13 | 2014-12-12 | Una composición farmacéutica que contiene ácido nicotínico y/o nicotinamida para su uso en influir beneficiosamente en los niveles de lípidos en sangre mediante la modificación de la microbiota intestinal |
Country Status (9)
| Country | Link |
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| EP (1) | EP3079675B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6895752B2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3079675T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2788866T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE048488T2 (cg-RX-API-DMAC7.html) |
| PL (1) | PL3079675T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3079675T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015086843A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
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| KR20160088436A (ko) | 2013-12-13 | 2016-07-25 | 코나리스 리써치 인스티튜트 아게 | 니코틴아미드 및 5-아미노살리실산의 조합을 포함하는, 장내 세균총에 유익한 영향을 미치거나 및/또는 위장 염증을 치료하기 위한 약학 조성물 |
| AR108231A1 (es) | 2016-04-19 | 2018-08-01 | Ferring Bv | Composiciones farmacéuticas orales de mesalazina |
| RU2738114C2 (ru) * | 2016-04-19 | 2020-12-08 | Конарис Рисёрч Инститьют Аг | Пероральные фармацевтические композиции никотинамида |
| KR102403048B1 (ko) * | 2016-06-13 | 2022-05-26 | 신유알엑스 인터내셔널 (타이완) 코포레이션 | 벤조산나트륨의 공-결정 및 그의 용도 |
| EP3468946A4 (en) | 2016-06-13 | 2020-02-12 | Syneurx International (Taiwan) Corp. | CO CRYSTALS OF LITHIUM BENZOATE AND USES THEREOF |
| WO2018198842A1 (ja) * | 2017-04-23 | 2018-11-01 | 国立大学法人九州大学 | 非アルコール性脂肪性肝疾患用治療剤 |
| EP3398600A1 (en) * | 2017-05-02 | 2018-11-07 | Salmon Pharma GmbH | Modified release nicotinamide |
| EP3398601A1 (en) * | 2017-05-02 | 2018-11-07 | Salmon Pharma GmbH | Nicotinamide for treating dyslipidemia |
| BR112020008561A2 (pt) * | 2017-10-30 | 2020-10-06 | Unilever Nv | usos de niacinamidas, niacinamidas, composição e método de fornecimento de proteção |
| US20220249535A1 (en) * | 2019-04-05 | 2022-08-11 | Rejuvenation Therapeutics | Compositions comprising nicotinamide adenine dinucleotide-related compounds and use thereof |
| CN113893262A (zh) * | 2021-09-29 | 2022-01-07 | 武汉英纽林生物科技有限公司 | 一种用于干预糖尿病前期空腹血糖偏高的nad+组合物及其制备方法和使用方法 |
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| US6129930A (en) * | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US5846983A (en) | 1996-02-09 | 1998-12-08 | Mayo Foundation For Medical Education And Research | Colonic delivery of nicotine to treat inflammatory bowel disease |
| US5736532A (en) | 1996-02-14 | 1998-04-07 | Furda; Ivan | Multifunctional fat absorption and blood cholesterol reducing formulation comprising chitosan |
| GB9614902D0 (en) | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
| US6713057B1 (en) * | 1999-02-24 | 2004-03-30 | The Johns Hopkins University | Compositions and methods for modulating serum cholesterol |
| GB0015242D0 (en) | 2000-06-22 | 2000-08-16 | Nycomed Amersham Plc | Stabiliser for radiopharmaceuticals |
| WO2002011725A1 (en) | 2000-08-08 | 2002-02-14 | Shionogi & Co., Ltd. | Inflammatory cytokine production inhibitors |
| US20040185097A1 (en) | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
| CA2553775A1 (en) | 2004-01-20 | 2005-08-11 | Richard F. Harty | Compositions and methods of treatment for inflammatory diseases |
| US20060264409A1 (en) | 2004-01-20 | 2006-11-23 | Harty Richard F | Compositions and methods of treatment for inflammatory diseases |
| US7326809B2 (en) | 2004-05-27 | 2008-02-05 | Antibe Therapeutics Inc. | Salts of 4- or 5-aminosalicylic acid |
| CA2581816A1 (en) | 2004-09-27 | 2006-04-06 | Sigmoid Biotechnologies Limited | Microcapsules comprising a methylxanthine and a corticosteroid |
| WO2007004613A1 (ja) | 2005-07-01 | 2007-01-11 | Ajinomoto Co., Inc. | 炎症性腸疾患治療薬及びＴＮＦ－α産生抑制剤 |
| ITMI20061932A1 (it) | 2006-10-09 | 2008-04-10 | Carlo Ghisalberti | Complessi a trasferimento di carica per uso medicale |
| EP2214518A4 (en) | 2007-10-19 | 2011-06-29 | Joel D Pardee | METABOLIC IMPROVEMENT TREATMENT |
| WO2009131537A1 (en) | 2008-04-25 | 2009-10-29 | Karolinska Institutet Innovations Ab | New therapy of treatment of the irritable bowel syndrome. |
| WO2009149058A2 (en) * | 2008-06-02 | 2009-12-10 | Dr. Reddy's Laboratories Ltd. | Modified release niacin formulations |
| WO2010040113A1 (en) | 2008-10-03 | 2010-04-08 | Salix Pharmaceuticals, Ltd. | Compositions and methods for the treatment of bowel diseases with granulated mesalamine |
| JP2011121889A (ja) | 2009-12-09 | 2011-06-23 | En Otsuka Pharmaceutical Co Ltd | 炎症性腸疾患用アミノ酸組成物 |
| JP2012102054A (ja) | 2010-11-11 | 2012-05-31 | Kyodo Milk Industry Co Ltd | 腸内ポリアミン増強剤 |
| WO2012090224A1 (en) | 2010-12-29 | 2012-07-05 | Nutracryst Therapeutics Private Limited | Novel cocrystals / molecular salts of mesalamine to be used as improved anti-inflammatory drug |
| SMT202100248T1 (it) | 2012-06-15 | 2021-05-07 | Conaris Res Institute Ag | Composizione farmaceutica contenente acido nicotinico e/o nicotinammide e/o triptofano per influenzare positivamente il microbiota intestinale |
| US10456389B2 (en) | 2013-06-14 | 2019-10-29 | Conaris Research Institute Ag | Extended release nicotinamide formulation |
| KR20160088436A (ko) | 2013-12-13 | 2016-07-25 | 코나리스 리써치 인스티튜트 아게 | 니코틴아미드 및 5-아미노살리실산의 조합을 포함하는, 장내 세균총에 유익한 영향을 미치거나 및/또는 위장 염증을 치료하기 위한 약학 조성물 |
| RU2738114C2 (ru) | 2016-04-19 | 2020-12-08 | Конарис Рисёрч Инститьют Аг | Пероральные фармацевтические композиции никотинамида |
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2014
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- 2014-12-12 WO PCT/EP2014/077646 patent/WO2015086843A2/en not_active Ceased
- 2014-12-12 PT PT148099088T patent/PT3079675T/pt unknown
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2019
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Also Published As
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| US20170027924A1 (en) | 2017-02-02 |
| WO2015086843A2 (en) | 2015-06-18 |
| JP7387299B2 (ja) | 2023-11-28 |
| DK3079675T3 (da) | 2020-04-20 |
| US10888555B2 (en) | 2021-01-12 |
| WO2015086843A3 (en) | 2015-08-06 |
| JP2017500311A (ja) | 2017-01-05 |
| JP6895752B2 (ja) | 2021-06-30 |
| PL3079675T3 (pl) | 2020-07-27 |
| EP3079675B1 (en) | 2020-02-12 |
| JP2019189616A (ja) | 2019-10-31 |
| EP3079675A2 (en) | 2016-10-19 |
| PT3079675T (pt) | 2020-03-05 |
| HUE048488T2 (hu) | 2020-07-28 |
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