ES2788159T3 - Sialil-di-Lewisa tal como se expresa en las glucoproteínas pero no en los glucolípidos como diana funcional del cáncer y sus anticuerpos - Google Patents

Sialil-di-Lewisa tal como se expresa en las glucoproteínas pero no en los glucolípidos como diana funcional del cáncer y sus anticuerpos Download PDF

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Publication number
ES2788159T3
ES2788159T3 ES16760541T ES16760541T ES2788159T3 ES 2788159 T3 ES2788159 T3 ES 2788159T3 ES 16760541 T ES16760541 T ES 16760541T ES 16760541 T ES16760541 T ES 16760541T ES 2788159 T3 ES2788159 T3 ES 2788159T3
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Prior art keywords
antibody
lewisa
sialyl
antibody fragment
binding
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ES16760541T
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English (en)
Spanish (es)
Inventor
Lindy Gillian Durrant
Mireille Vankemmelbeke
Silvana Tivadar
Tina Parsons
Richard Mcintosh
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Scancell Ltd
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Scancell Ltd
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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ES16760541T 2015-08-25 2016-08-25 Sialil-di-Lewisa tal como se expresa en las glucoproteínas pero no en los glucolípidos como diana funcional del cáncer y sus anticuerpos Active ES2788159T3 (es)

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PCT/GB2016/052647 WO2017033020A1 (en) 2015-08-25 2016-08-25 Sialyl-di-lewis a as expressed on glycoproteins but not glycolipids as a functional cancer target and antibodies thereto

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WO2015053871A2 (en) * 2013-08-26 2015-04-16 MabVax Therapeutics, Inc. NUCLEIC ACIDS ENCODING HUMAN ANTIBODIES TO SIALYL-LEWISa
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GB201910900D0 (en) 2019-07-31 2019-09-11 Scancell Ltd Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
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CA2996436A1 (en) 2017-03-02
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KR102713512B1 (ko) 2024-10-04
WO2017033020A1 (en) 2017-03-02
EP3341412A1 (en) 2018-07-04
CN108137695B (zh) 2022-03-29
US10835618B2 (en) 2020-11-17
ZA201801994B (en) 2019-01-30
PT3341412T (pt) 2020-05-21
US20180236095A1 (en) 2018-08-23
BR112018003779A2 (pt) 2018-09-25
JP2018529328A (ja) 2018-10-11
KR20180100541A (ko) 2018-09-11

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