ES2778677T3 - Calibración y/o detección de errores en un dispositivo de medición óptica para muestras biológicas - Google Patents
Calibración y/o detección de errores en un dispositivo de medición óptica para muestras biológicas Download PDFInfo
- Publication number
- ES2778677T3 ES2778677T3 ES15200769T ES15200769T ES2778677T3 ES 2778677 T3 ES2778677 T3 ES 2778677T3 ES 15200769 T ES15200769 T ES 15200769T ES 15200769 T ES15200769 T ES 15200769T ES 2778677 T3 ES2778677 T3 ES 2778677T3
- Authority
- ES
- Spain
- Prior art keywords
- measurement
- measurement channel
- channel
- optical
- reference factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 203
- 238000001514 detection method Methods 0.000 title claims abstract description 150
- 239000012472 biological sample Substances 0.000 title claims abstract description 113
- 238000005259 measurement Methods 0.000 claims abstract description 538
- 238000000034 method Methods 0.000 claims abstract description 123
- 238000003780 insertion Methods 0.000 claims description 6
- 230000037431 insertion Effects 0.000 claims description 6
- 238000010998 test method Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 description 24
- 230000008859 change Effects 0.000 description 19
- 238000012545 processing Methods 0.000 description 17
- 230000003068 static effect Effects 0.000 description 16
- 239000003153 chemical reaction reagent Substances 0.000 description 13
- 239000013307 optical fiber Substances 0.000 description 12
- 238000004458 analytical method Methods 0.000 description 10
- 230000005540 biological transmission Effects 0.000 description 10
- 238000012937 correction Methods 0.000 description 8
- 238000000338 in vitro Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000012491 analyte Substances 0.000 description 4
- 238000005345 coagulation Methods 0.000 description 4
- 230000015271 coagulation Effects 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- 238000011534 incubation Methods 0.000 description 4
- 230000004044 response Effects 0.000 description 4
- 230000032683 aging Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000011068 loading method Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000003753 real-time PCR Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000005336 cracking Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 239000007850 fluorescent dye Substances 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 206010003445 Ascites Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 210000003567 ascitic fluid Anatomy 0.000 description 1
- 238000003705 background correction Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 210000000695 crystalline len Anatomy 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000000295 emission spectrum Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000002493 microarray Methods 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012883 sequential measurement Methods 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 210000001179 synovial fluid Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00693—Calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
- G01N21/474—Details of optical heads therefor, e.g. using optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/127—Calibration; base line adjustment; drift compensation
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Quality & Reliability (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15200769.6A EP3182096B1 (en) | 2015-12-17 | 2015-12-17 | Calibration and/or error detection in an optical measurement device for biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2778677T3 true ES2778677T3 (es) | 2020-08-11 |
Family
ID=54979437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15200769T Active ES2778677T3 (es) | 2015-12-17 | 2015-12-17 | Calibración y/o detección de errores en un dispositivo de medición óptica para muestras biológicas |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11353471B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3182096B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6799454B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN106896062B (cg-RX-API-DMAC7.html) |
| ES (1) | ES2778677T3 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016210413A1 (en) | 2015-06-26 | 2016-12-29 | Abbott Laboratories | Reaction vessel moving member for moving reaction vessels from a processing track to a rotating device in a diagnostic analyzer |
| JP6745397B2 (ja) * | 2016-07-21 | 2020-08-26 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | キュベット間の基準測定値を用いた電源ランプの強度ドリフト効果の除去 |
| EP3290905B1 (en) * | 2016-09-05 | 2022-10-19 | F. Hoffmann-La Roche AG | Signal offset determination and correction |
| JP6630947B2 (ja) * | 2017-09-01 | 2020-01-15 | ウシオ電機株式会社 | マイクロプレートリーダー |
| AU2019213498B2 (en) * | 2018-01-30 | 2024-08-01 | Grainsense Oy | A method for calibrating an integrating cavity |
| CN112041076B (zh) * | 2018-04-23 | 2023-04-18 | 迈恩医疗解决方案有限公司 | 用于从液体介质获得测量信号的自动分析器和光学测量方法 |
| EP3784400A1 (de) | 2018-04-23 | 2021-03-03 | Meon Medical Solutions GmbH & Co. KG | Optische messeinheit und optisches messverfahren zur gewinnung von messsignalen von flüssigen medien |
| EP3614128B1 (en) * | 2018-08-22 | 2023-04-26 | F. Hoffmann-La Roche AG | A method to correct signal light intensities measured by a detector of a detection unit in a laboratory instrument |
| CA3126148A1 (en) | 2019-01-10 | 2020-07-16 | Travera LLC | Calibration of a functional biomarker instrument |
| WO2020146727A1 (en) | 2019-01-10 | 2020-07-16 | Selim Olcum | Identifying cancer therapies |
| CN114174834B (zh) * | 2019-08-06 | 2025-08-15 | 株式会社岛津制作所 | 生物化学分析装置和生物化学分析方法 |
| KR102522278B1 (ko) * | 2021-10-29 | 2023-04-17 | 주식회사 신코 | 듀얼 어레이 센서를 이용한 고속 흡광도 측정 마이크로플레이트 리더기 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4591550A (en) | 1984-03-01 | 1986-05-27 | Molecular Devices Corporation | Device having photoresponsive electrode for determining analytes including ligands and antibodies |
| JPS62115348A (ja) * | 1985-09-30 | 1987-05-27 | モレキユラ− デバイスイズ コ−ポレイシヨン | 多ビ−ムによる光度測定装置および測定方法 |
| US7217574B2 (en) * | 2000-10-30 | 2007-05-15 | Sru Biosystems, Inc. | Method and apparatus for biosensor spectral shift detection |
| JP3838501B2 (ja) * | 2001-12-05 | 2006-10-25 | Kddi株式会社 | 光バースト信号ルーチング方式 |
| EP1562036A3 (en) * | 2002-08-28 | 2005-09-28 | Fuji Photo Film Co., Ltd. | Measuring apparatus |
| JP4483333B2 (ja) * | 2004-02-17 | 2010-06-16 | 株式会社島津製作所 | 光測定装置における測定方法及びチャンネル間偏差測定用標準器 |
| US7339668B2 (en) | 2005-10-18 | 2008-03-04 | Thermo Electron Scientific Instruments Llc | Spectrometer for analysis of multiple samples |
| CN200950139Y (zh) | 2006-07-19 | 2007-09-19 | 北京工业大学 | 用于生物pcr微通道荧光检测的标准芯片 |
| US7674616B2 (en) * | 2006-09-14 | 2010-03-09 | Hemosense, Inc. | Device and method for measuring properties of a sample |
| JP2009053029A (ja) | 2007-08-27 | 2009-03-12 | Olympus Corp | 自動分析装置 |
| US20110001963A1 (en) * | 2009-07-02 | 2011-01-06 | Durack Gary P | System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system |
| US9091637B2 (en) | 2009-12-04 | 2015-07-28 | Duke University | Smart fiber optic sensors systems and methods for quantitative optical spectroscopy |
| EP2630253B1 (en) * | 2010-10-20 | 2014-11-12 | Analogic Corporation | Method of calibrating and correcting color-bleed factors for color separation in dna analysis |
| CA2866641C (en) * | 2012-03-09 | 2016-01-26 | Siemens Healthcare Diagnostics Inc. | Calibration method for reagent card analyzers |
| GB2506375B (en) * | 2012-09-27 | 2017-10-18 | Epistem Ltd | Data processing and analysis systems |
| CN103528952B (zh) | 2013-10-25 | 2016-07-06 | 中国科学院合肥物质科学研究院 | 一种开放光路式气体分析仪通量校正测量装置及测量方法 |
| MX361975B (es) * | 2013-12-19 | 2018-12-19 | Halliburton Energy Services Inc | Estandarización de sensores cruzados. |
| CN104198382A (zh) | 2014-06-18 | 2014-12-10 | 上海理工大学 | 基于检测农药残留的双通道检测装置及方法 |
-
2015
- 2015-12-17 EP EP15200769.6A patent/EP3182096B1/en active Active
- 2015-12-17 ES ES15200769T patent/ES2778677T3/es active Active
-
2016
- 2016-12-13 US US15/376,704 patent/US11353471B2/en active Active
- 2016-12-15 CN CN201611157483.1A patent/CN106896062B/zh active Active
- 2016-12-15 JP JP2016242802A patent/JP6799454B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3182096A1 (en) | 2017-06-21 |
| US11353471B2 (en) | 2022-06-07 |
| US20170176478A1 (en) | 2017-06-22 |
| JP2017111145A (ja) | 2017-06-22 |
| CN106896062B (zh) | 2020-11-06 |
| CN106896062A (zh) | 2017-06-27 |
| JP6799454B2 (ja) | 2020-12-16 |
| EP3182096B1 (en) | 2020-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2778677T3 (es) | Calibración y/o detección de errores en un dispositivo de medición óptica para muestras biológicas | |
| EP2317304B1 (en) | Sample analysis device | |
| EP1887356B1 (en) | Automatic analyzer | |
| EP1840555A1 (en) | Sample analyzer and sample analyzing method | |
| US10379046B2 (en) | Method and system for multiplexed time-resolved fluorescence detection | |
| JP5801004B2 (ja) | 試薬カード分析器の較正方法 | |
| CN113841043B (zh) | 水质分析系统、传感器模块、校正用设备以及水质分析系统的校正方法 | |
| US20120120388A1 (en) | System for Performing Scattering and Absorbance Assays | |
| CN113945553B (zh) | 改进多个拉曼分析仪装置之间的校准传递的系统和方法 | |
| JP7206570B2 (ja) | 分析装置 | |
| US20180128676A1 (en) | System for optically monitoring operating conditions in a sample analyzing apparatus | |
| EP2584342B1 (en) | Method for quantitative optical measurements and laboratory apparatus | |
| US10856391B2 (en) | Method to correct signal light intensities measured by a detector of a detection unit in a laboratory instrument | |
| US9575083B2 (en) | Automatic analysis apparatus | |
| CN113777334A (zh) | 自动分析仪及其光源监测方法、校准方法和存储介质 | |
| EP3344978B1 (en) | Apparatus and method for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample | |
| US10458997B2 (en) | Signal offset determination and correction | |
| WO2020116058A1 (ja) | 分析装置及び分析方法 | |
| US20080206100A1 (en) | Automatic analyzer | |
| KR102241251B1 (ko) | 다중 블롯 검사 자동화 시스템 | |
| KR102224374B1 (ko) | 형광 방식 면역 분석 진단 장치용 기준 카세트 | |
| KR20240176006A (ko) | 광학 기술을 이용한 기생충란 검출 방법 및 장치 | |
| JP2006162355A (ja) | 装置組込み型光度計の波長確認方法及び自動分析装置 |