ES2769794T3 - Método para preparar un aislado de planta de Cannabis que comprende delta-9-tetrahidrocannabinol - Google Patents

Método para preparar un aislado de planta de Cannabis que comprende delta-9-tetrahidrocannabinol Download PDF

Info

Publication number
ES2769794T3
ES2769794T3 ES13724007T ES13724007T ES2769794T3 ES 2769794 T3 ES2769794 T3 ES 2769794T3 ES 13724007 T ES13724007 T ES 13724007T ES 13724007 T ES13724007 T ES 13724007T ES 2769794 T3 ES2769794 T3 ES 2769794T3
Authority
ES
Spain
Prior art keywords
thc
extract
weight
cannabis plant
film evaporation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13724007T
Other languages
English (en)
Spanish (es)
Inventor
Cid Maria Vanesa Fernandez
Houten Dennis Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Echo Pharmaceuticals BV
Original Assignee
Echo Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Echo Pharmaceuticals BV filed Critical Echo Pharmaceuticals BV
Application granted granted Critical
Publication of ES2769794T3 publication Critical patent/ES2769794T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES13724007T 2012-05-03 2013-05-03 Método para preparar un aislado de planta de Cannabis que comprende delta-9-tetrahidrocannabinol Active ES2769794T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12166661 2012-05-03
PCT/NL2013/050339 WO2013165251A1 (en) 2012-05-03 2013-05-03 Cannabis plant isolate comprising /\9-tetrahydrocannabinol and a method for preparing such an isolate

Publications (1)

Publication Number Publication Date
ES2769794T3 true ES2769794T3 (es) 2020-06-29

Family

ID=48468725

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13724007T Active ES2769794T3 (es) 2012-05-03 2013-05-03 Método para preparar un aislado de planta de Cannabis que comprende delta-9-tetrahidrocannabinol

Country Status (13)

Country Link
US (1) US20150126754A1 (enExample)
EP (1) EP2844243B8 (enExample)
JP (1) JP2015515977A (enExample)
CN (1) CN104619318A (enExample)
AU (1) AU2013257322A1 (enExample)
CA (1) CA2872528C (enExample)
DK (1) DK2844243T3 (enExample)
ES (1) ES2769794T3 (enExample)
IN (1) IN2014DN09507A (enExample)
PL (1) PL2844243T3 (enExample)
PT (1) PT2844243T (enExample)
SI (1) SI2844243T1 (enExample)
WO (1) WO2013165251A1 (enExample)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9155767B2 (en) 2012-10-18 2015-10-13 Andrew D. Hospodor Essential element management
JP6581509B2 (ja) 2013-02-28 2019-09-25 ティーウィノット テクノロジーズ リミテッド 化合物を合成する化学工学プロセス及び装置
GB2536150A (en) * 2013-11-11 2016-09-07 The Werc Shop Llc Solvent-free processing, system and methods
CA2942867C (en) 2014-03-18 2022-08-30 Izun Pharmaceuticals Corp. Protein-bound cannabinoid compositions
WO2016004121A1 (en) * 2014-07-01 2016-01-07 MJAR Holdings, LLC High cannabidiol cannabis strains
AU2015308136B2 (en) 2014-08-25 2020-07-09 Teewinot Technologies Limited Apparatus and methods for the simultaneous production of cannabinoid compounds
BR122021018502B1 (pt) * 2014-10-21 2022-05-03 United Cannabis Corp Formulação de canabinoide líquida
US9808494B2 (en) * 2015-01-22 2017-11-07 Rm3 Labs, Llc Process for the extraction of cannabinoids from cannabis using lipids as an extraction solvent
US10238745B2 (en) 2015-01-31 2019-03-26 Constance Therapeutics, Inc. Cannabinoid composition and products including α-tocopherol
WO2016123475A1 (en) * 2015-01-31 2016-08-04 Constance Therapeutics, Inc. Methods for preparation of cannabis oil extracts and compositions
US10059684B2 (en) 2015-05-07 2018-08-28 Axim Biotechnologies, Inc. Process to extract and purify Δ9-tetrahydrocannabinol
CA3176674A1 (en) * 2015-05-18 2016-11-24 5071, Inc. Homogenous cannabis compositions and methods of making the same
WO2016205923A1 (en) * 2015-06-25 2016-12-29 Compressed Perforated Puck Technologies Inc. Ingestible plant source pill and method
EP3150264A1 (de) * 2015-09-30 2017-04-05 Bionorica Ethics GmbH Vakuumdestillation zur anreicherung von cbd
WO2017091764A1 (en) 2015-11-24 2017-06-01 Constance Therapeutics, Inc. Cannabis oil compositions and methods for preparation thereof
EP3766488A1 (en) * 2016-04-12 2021-01-20 Schaneville, Scott Ingestible films having substances from hemp or cannabis
CA3021446A1 (en) * 2016-04-18 2017-10-26 Kenneth Michael MORROW Isolation of plant extracts
US10588974B2 (en) 2016-04-22 2020-03-17 Receptor Holdings, Inc. Fast-acting plant-based medicinal compounds and nutritional supplements
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
EP3474844B1 (en) 2016-06-28 2022-07-27 Trichomeshell Ltd. A dosage form for vaporization and smoking
US10143706B2 (en) 2016-06-29 2018-12-04 Cannscience Innovations, Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
KR20190035791A (ko) 2016-08-03 2019-04-03 젤다 테라퓨틱스 오퍼레이션즈 피티와이 엘티디 카나비스 조성물
PE20200676A1 (es) * 2016-08-03 2020-06-11 Zelda Therapeutics Operations Pty Ltd Composicion de cannabis
MX386086B (es) * 2016-08-03 2025-03-18 Zelda Therapeutics Operations Pty Ltd Composicion de cannabis
IL248150B (en) 2016-09-29 2018-05-31 Garti Nissim Method for selective extraction of cannabinoids from a plant source
IL248149B (en) 2016-09-29 2020-03-31 Garti Nissim Formulations of dilutable cannabinoids and processes for their preparation
IL248148B (en) 2016-09-29 2021-09-30 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd A method for extracting a compound from plant origin
EA201892396A1 (ru) 2016-12-02 2019-04-30 Ресептор Лайф Сайенсиз, Инк. Быстродействующие растительные лекарственные соединения и биологически активные добавки
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US10773184B2 (en) 2016-12-30 2020-09-15 X Traxion, Llc Extraction of compounds from cannabis
EP3592371B1 (en) 2017-03-09 2023-06-07 Izun Pharmaceuticals Corp. Stabilized protein-bound cannabinoid compositions
US10034907B1 (en) 2017-04-07 2018-07-31 Gerald Echavarry Flavored and edible cannabinoid composition and method of manufacturing
US10828341B2 (en) * 2017-04-18 2020-11-10 Jose Rivas Method for preparation of pharmacologically-relevant compounds from botanical sources
US11759724B2 (en) 2017-04-18 2023-09-19 Jose Rivas Method and apparatus for preparation of pharmacologically-relevant compounds from botanical sources
US11845022B2 (en) 2017-04-18 2023-12-19 Premium Extracts, Inc. Method and apparatus for dehydration and decarboxylation of cannabis
WO2018232448A1 (en) 2017-06-19 2018-12-27 Zelda Therapeutics Operations Pty Ltd Sleep disorder compositions and treatments thereof
US10189762B1 (en) * 2017-07-07 2019-01-29 Orochem Technologies, Inc. Process for purification and separation of cannabinoids, from dried hemp and cannabis leaves
US10272360B2 (en) 2017-08-05 2019-04-30 Priya Naturals, Inc. Phytochemical extraction system and methods to extract phytochemicals from plants including plants of the family Cannabaceae sensu stricto
AU2018325465A1 (en) * 2017-09-02 2020-05-28 Scientific Holdings, Llc Tetrahydrocannabinol modulators
EP3453397A1 (en) 2017-09-12 2019-03-13 Albert Jan Dijkstra Processes for the isolation of a cannabinoid extract and product from cannabis plant material
US10406453B2 (en) 2017-09-29 2019-09-10 NextLeaf Solutions Ltd. Cannabinoid extraction process using brine
US9987567B1 (en) * 2017-09-29 2018-06-05 NextLeaf Solutions Ltd. Cannabinoid extraction process and system
EP3745884A1 (en) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hemp powder
CA3073093A1 (en) 2018-08-03 2020-02-06 Biomass Oil Separation Solutions, Llc Processes and apparatus for extraction of substances and enriched extracts from plant material
US11254633B2 (en) 2018-10-05 2022-02-22 Jonas Alcirdas Navickas Cannabis thin layer decarboxylation
US11324718B2 (en) 2018-10-09 2022-05-10 Sartorius Chromatography Equipment Method for purifying cannabinoids
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP3873459A1 (en) * 2018-10-31 2021-09-08 Enantia, S.L. Solid compositions of cocrystals of cannabinoids
US12303487B2 (en) 2018-11-19 2025-05-20 Spoke Sciences, Inc. N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions
US10765966B2 (en) 2019-02-06 2020-09-08 Heinkel Filtering Systems. Inc. Biomass extraction and centrifugation systems and methods
US10493377B1 (en) 2019-02-06 2019-12-03 Heinkel Filtering Systems, Inc. Biomass extraction and centrifugation systems and methods
AU2020268218B2 (en) 2019-05-03 2022-09-08 Zyus Life Sciences Inc. Formulation for pain management
US12178797B2 (en) 2019-05-03 2024-12-31 Zyus Life Sciences Inc. Formulation for pain management
US12220396B2 (en) 2019-05-03 2025-02-11 Zyus Life Sciences Inc. Formulation for pain management
US10799546B1 (en) 2019-07-26 2020-10-13 Biomass Oil Separation Solutions, Llc Modular, integrated process and apparatus for extracting, refining and remediating active substances from plant material
US10717056B1 (en) 2019-09-09 2020-07-21 Michael Cem Gokay Method and apparatus for purification of cannabinoid extracts
US20210213082A1 (en) * 2019-10-24 2021-07-15 Fermented Farmer, LLC Botanical Synergistic Activated/Native and Equivalents Thereof
US10751640B1 (en) 2019-10-30 2020-08-25 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
US10858303B1 (en) 2019-10-30 2020-12-08 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
US11291699B1 (en) 2019-12-13 2022-04-05 Delmarva Hemp, LLC Method for solvent-free extraction and concentration of full spectrum of cannabinoids in a carrier oil
US20230398080A1 (en) * 2020-01-02 2023-12-14 Yissum Research Development Comp Any Of The Hebrew University Of Jerusalem Ltd. Floating drug delivery systems comprising cannabinoids
IL294598A (en) 2020-01-10 2022-09-01 Real Isolates Llc Methods for obtaining compounds from plant or fungal material, suitable compositions and their uses
CN111239293A (zh) * 2020-03-02 2020-06-05 福建省中科生物股份有限公司 一种萜酚有关物质的hplc-pda检测方法
US20220395546A1 (en) * 2021-06-11 2022-12-15 eHempHouse Corp. Methods and compositions for the extraction of phytochemicals from plant material
AU2022376838A1 (en) 2021-10-26 2024-05-23 Dove Innovation Pty Limited Methods of treating endometrial cancer using hemp extract
AU2022379618A1 (en) 2021-10-26 2024-05-23 Dove Innovation Pty Limited Methods of treating endometriosis and other non-cancer gynecological disorders with hemp extract
AU2022376837A1 (en) 2021-10-26 2024-05-23 Dove Innovation Pty Limited Systems and methods for producing hemp extracts and compositions
US12122757B2 (en) * 2021-11-24 2024-10-22 CLS Labs, Inc. Cannabidiol extraction and conversion process
KR20240142502A (ko) 2022-01-28 2024-09-30 베르타니컬 게엠베하 식물 추출물의 제조 방법
CN115228135B (zh) * 2022-06-25 2024-02-20 永胜三可口生物开发有限责任公司 一种降低火麻油中四氢大麻酚含量的装置系统
AU2023367739A1 (en) 2022-10-26 2025-06-12 Dove Innovation Pty Limited Stabilized compositions comprising cannabidiol
US12097211B2 (en) 2022-10-26 2024-09-24 Ecofibre USA Inc. Methods of treating estrogen sensitive diseases with cannabis extract
EP4591855A1 (en) 2024-01-23 2025-07-30 Echo Pharmaceuticals B.V. Stable dronabinol compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039795A1 (en) * 1998-10-26 2002-04-04 Elsohly Et Al Method of preparing delta-9-tetrahydrocannabinol
CN1642934A (zh) * 2002-02-01 2005-07-20 分析化学品有限公司 Δ9四氢大麻酚的制备
GB2408978B (en) * 2002-09-23 2006-04-05 Gw Pharma Ltd Methods of preparing delta-9 tetrahydrocannabinol from plant material
GB0222077D0 (en) * 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material

Also Published As

Publication number Publication date
WO2013165251A1 (en) 2013-11-07
EP2844243B1 (en) 2019-11-13
PT2844243T (pt) 2020-01-17
CA2872528A1 (en) 2013-11-07
US20150126754A1 (en) 2015-05-07
JP2015515977A (ja) 2015-06-04
EP2844243A1 (en) 2015-03-11
SI2844243T1 (sl) 2020-02-28
CA2872528C (en) 2021-01-05
AU2013257322A1 (en) 2014-11-20
IN2014DN09507A (enExample) 2015-07-17
EP2844243B8 (en) 2019-12-18
PL2844243T3 (pl) 2020-05-18
DK2844243T3 (da) 2020-02-03
CN104619318A (zh) 2015-05-13

Similar Documents

Publication Publication Date Title
ES2769794T3 (es) Método para preparar un aislado de planta de Cannabis que comprende delta-9-tetrahidrocannabinol
ES2759568T3 (es) Aislado de cannabidiol de cáñamo industrial y uso del mismo en preparaciones farmacéuticas y/o cosméticas
US10646526B2 (en) Cannabis extraction method and compositions
US11040295B2 (en) Method and apparatus for extracting plant oils using ethanol water
US10143706B2 (en) Decarboxylated cannabis resins, uses thereof and methods of making same
Martinez-Correa et al. Integrated extraction process to obtain bioactive extracts of Artemisia annua L. leaves using supercritical CO2, ethanol and water
HK1251197A1 (zh) 用於富集大麻二酚的真空蒸馏
US9539295B2 (en) Cannabidiol (CBD) enriched alcohol
EP3634452A1 (en) Sublingual cannabinoid compositions
ES2882493T3 (es) Nuevo extracto de aquenio Silybum marianum y utilizaciones del mismo en dermatología y dermocosméticos
Malabadi et al. Cannabis sativa: Extraction Methods for Phytocannabinoids-An Update
CA3133582A1 (en) Carrier system for preparing herbaceous extracts
KR20250134118A (ko) 신경퇴행성 질환 또는 장애 및 암 치료에 있어서의 칸나비노이드 조성물 및 이의 용도
Visht et al. Effect of Cholesterol and Different Solvents on Particle Size, Zeta Potential and Drug Release of Eucalyptus Oil Phytosome
US10548931B1 (en) Method for treating cannabis induced anxiety
Tasnim et al. Exploration of analgesic, laxative and immunomodulatory effects of leaves and twigs of Euphorbia tirucalli along with in silico analysis
Singh et al. FORMULATION & CHARACTERIZATION OF PHYTOSOSMES CONTAINING MEDICINAL PLANT RHEUM EMODI
Cecati et al. Design of Cannabis sativa (L.) Emulsion: Characterization and Quantification of Cannabinoids and Terpenes
JP2025503278A (ja) 植物抽出物の製造方法
BR102015007348A2 (pt) processo de produção de extrato e fração de tropaeolum majus l. com concentração padronizada de marcadores e uso do extrato e fração.