ES273453A1 - Improvements in or relating to pyrazolidine-3,5-dione derivatives - Google Patents

Improvements in or relating to pyrazolidine-3,5-dione derivatives

Info

Publication number
ES273453A1
ES273453A1 ES0273453A ES273453A ES273453A1 ES 273453 A1 ES273453 A1 ES 273453A1 ES 0273453 A ES0273453 A ES 0273453A ES 273453 A ES273453 A ES 273453A ES 273453 A1 ES273453 A1 ES 273453A1
Authority
ES
Spain
Prior art keywords
pyrazolidine
relating
compounds
dione derivatives
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0273453A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH18061A external-priority patent/CH383387A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES273453A1 publication Critical patent/ES273453A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of general formula <FORM:1007578/C2/1> wherein R is alkyl (1-4 C), cycloalkyl, or aralkyl (7-10 C) and their preparation by condensing p,p1 - trifluoromethyl - hydrazobenzene with a functional malonic acid derivative of which the free acid has the formula R-CH(COOH)2. Cyclohexyl malonic acid dichloride is obtained from the acid with phosphorus pentachloride. Pharmaceutical compositions comprise compounds (I) with carriers. The compounds are antiphlogistics. Specification 1,007,579 is referred to.
ES0273453A 1961-01-06 1962-01-05 Improvements in or relating to pyrazolidine-3,5-dione derivatives Expired ES273453A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH18061A CH383387A (en) 1961-01-06 1961-01-06 Process for the preparation of new heterocyclic compounds
CH1098361 1961-09-21

Publications (1)

Publication Number Publication Date
ES273453A1 true ES273453A1 (en) 1962-07-01

Family

ID=25683786

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0273453A Expired ES273453A1 (en) 1961-01-06 1962-01-05 Improvements in or relating to pyrazolidine-3,5-dione derivatives

Country Status (2)

Country Link
ES (1) ES273453A1 (en)
GB (1) GB1007578A (en)

Also Published As

Publication number Publication date
GB1007578A (en) 1965-10-13

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