ES272326A1 - Improvements in and relating to iminodibenzyl compounds - Google Patents

Improvements in and relating to iminodibenzyl compounds

Info

Publication number
ES272326A1
ES272326A1 ES0272326A ES272326A ES272326A1 ES 272326 A1 ES272326 A1 ES 272326A1 ES 0272326 A ES0272326 A ES 0272326A ES 272326 A ES272326 A ES 272326A ES 272326 A1 ES272326 A1 ES 272326A1
Authority
ES
Spain
Prior art keywords
formula
compound
reacting
reaction
iminodibenzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0272326A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES272326A1 publication Critical patent/ES272326A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises <FORM:0940598/C2/1> of formula <FORM:0940598/C2/2> obtained either by reacting 3-chloro-iminodibenzyl with an ester of an alcohol of formula <FORM:0940598/C2/3> or by heating a compound of formula <FORM:0940598/C2/4> to remove carbon dioxide the compound of formula III may be obtained by reacting <FORM:0940598/C2/5> with 3-dimethylamino-2-methyl-1-propanol. Salts of the compound of formula I may be obtained by reaction with acids. The material prepared as above is racemic and may be separated into its optical isomers by reaction with an optically active acid. The compound of formula I has serotoninantagonistic, anti-emetic, anti-inflammatory and anti-allergic properties and may be used as a tranquiliser. It may be formed into tablets or solutions with gelatine, sugar, dextrose, lactose, starch, stearic acid, magnesium or calcium stearate, methyl cellulose, talcum, cholesterol, activated silica, polyvinyl-pyrrolidone, glycerol, glycols and water.
ES0272326A 1960-11-25 1961-11-24 Improvements in and relating to iminodibenzyl compounds Expired ES272326A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1325360 1960-11-25

Publications (1)

Publication Number Publication Date
ES272326A1 true ES272326A1 (en) 1962-07-01

Family

ID=4390759

Family Applications (2)

Application Number Title Priority Date Filing Date
ES0272327A Expired ES272327A1 (en) 1960-11-25 1961-11-24 Improvements in and relating to iminodibenzyl compounds
ES0272326A Expired ES272326A1 (en) 1960-11-25 1961-11-24 Improvements in and relating to iminodibenzyl compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES0272327A Expired ES272327A1 (en) 1960-11-25 1961-11-24 Improvements in and relating to iminodibenzyl compounds

Country Status (3)

Country Link
BE (1) BE610738A (en)
ES (2) ES272327A1 (en)
GB (1) GB940598A (en)

Also Published As

Publication number Publication date
ES272327A1 (en) 1962-06-16
GB940598A (en) 1963-10-30
BE610738A (en) 1962-05-24

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