ES2721752T3 - Reducción de la genotoxicidad in vitro de extractos de polen mediante la eliminación de flavonoides - Google Patents
Reducción de la genotoxicidad in vitro de extractos de polen mediante la eliminación de flavonoides Download PDFInfo
- Publication number
- ES2721752T3 ES2721752T3 ES16184996T ES16184996T ES2721752T3 ES 2721752 T3 ES2721752 T3 ES 2721752T3 ES 16184996 T ES16184996 T ES 16184996T ES 16184996 T ES16184996 T ES 16184996T ES 2721752 T3 ES2721752 T3 ES 2721752T3
- Authority
- ES
- Spain
- Prior art keywords
- pollen
- flavonoids
- eliminating
- reduction
- pollen extracts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Jellies, Jams, And Syrups (AREA)
- Saccharide Compounds (AREA)
Abstract
Un extracto de polen purificado que contiene alérgenos de polen, en el que cada flavonoide está contenido en una cantidad que es inferior a 0,001 g por 100 g de fracción derivada de polen seco, expresada en equivalente de aglucona, en el que dicho extracto de alérgeno de polen purificado se puede obtener mediante un procedimiento que comprende una etapa de ultrafiltración de un extracto de alérgeno de polen acuoso en una membrana de 1-10 kDa y al menos 5 volúmenes de una disolución de bicarbonato de amonio, y una etapa de filtración estéril a través de un filtro de 0,22 μm.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305517 | 2009-06-05 | ||
| EP09174479A EP2258391A1 (en) | 2009-06-05 | 2009-10-29 | Reduction of in vitro genotoxicity of pollen extracts by removal of flavonoids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2721752T3 true ES2721752T3 (es) | 2019-08-05 |
Family
ID=41396404
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10724799.1T Active ES2625977T3 (es) | 2009-06-05 | 2010-06-07 | Reducción de la genotoxicidad in vitro de extractos de polen mediante la eliminación de flavonoides |
| ES16184996T Active ES2721752T3 (es) | 2009-06-05 | 2010-06-07 | Reducción de la genotoxicidad in vitro de extractos de polen mediante la eliminación de flavonoides |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10724799.1T Active ES2625977T3 (es) | 2009-06-05 | 2010-06-07 | Reducción de la genotoxicidad in vitro de extractos de polen mediante la eliminación de flavonoides |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9795644B2 (es) |
| EP (3) | EP2258391A1 (es) |
| CA (1) | CA2764406C (es) |
| CY (1) | CY1120484T1 (es) |
| DK (2) | DK2459217T3 (es) |
| ES (2) | ES2625977T3 (es) |
| HR (2) | HRP20170799T1 (es) |
| HU (2) | HUE033871T2 (es) |
| LT (2) | LT2459217T (es) |
| PL (2) | PL3141262T3 (es) |
| PT (2) | PT3141262T (es) |
| SI (2) | SI3141262T1 (es) |
| WO (1) | WO2010139809A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2692732A1 (en) | 2012-08-03 | 2014-02-05 | Stallergenes S.A. | Novel allergen from ragweed pollen and uses thereof |
| CN107884480A (zh) * | 2016-09-30 | 2018-04-06 | 九芝堂股份有限公司 | 一种结肠宁制剂的检测方法 |
| FR3059429B1 (fr) * | 2016-11-30 | 2020-09-04 | Laboratoires Arkopharma | Procede permettant d'imputer une reponse non negative obtenue dans un test de mutation reverse sur bacteries, realise a partir d'une preparation pharmaceutique, cosmetique ou nutritionnelle, a au moins un constituant identifie comme mutagene in vitro |
| US11617789B2 (en) * | 2018-11-09 | 2023-04-04 | Jubilant HollisterStier LLC | Process for the preparation of allergenic extracts |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234569A (en) * | 1978-10-04 | 1980-11-18 | The Johns Hopkins University | Production of aldehyde-treated allergen-containing substances |
| US6297426B1 (en) * | 1990-06-12 | 2001-10-02 | Pioneer Hi-Bred International, Inc. | Methods of mediating female fertility in plants |
| DE69217395T2 (de) | 1992-09-21 | 1997-05-22 | C.B.F. Leti, S.A., Tres Cantos, Madrid | Verfahren zur reinigung von waessrigen extrakten, die allergenische proteine enthalten, so erhaltene extrakte und ihre verwendung |
| US20030077265A1 (en) * | 2001-07-06 | 2003-04-24 | Rod Ausich | Isolation and purification of proteinase inhibitor ll |
| CN1468859A (zh) * | 2002-07-19 | 2004-01-21 | 复旦大学 | 蒲黄总黄酮提取物及其制备工艺和用途 |
| DK1834648T3 (da) * | 2006-03-14 | 2013-11-04 | Alk Abello As | Fremgangsmåde til fremstilling af et allergenekstrakt |
| US7887821B2 (en) * | 2007-12-20 | 2011-02-15 | Alk-Abello A/S | Process for producing an allergen extract |
-
2009
- 2009-10-29 EP EP09174479A patent/EP2258391A1/en not_active Withdrawn
-
2010
- 2010-06-07 CA CA2764406A patent/CA2764406C/en not_active Expired - Fee Related
- 2010-06-07 EP EP10724799.1A patent/EP2459217B1/en active Active
- 2010-06-07 PL PL16184996T patent/PL3141262T3/pl unknown
- 2010-06-07 DK DK10724799.1T patent/DK2459217T3/en active
- 2010-06-07 EP EP16184996.3A patent/EP3141262B1/en active Active
- 2010-06-07 LT LTEP10724799.1T patent/LT2459217T/lt unknown
- 2010-06-07 US US13/376,238 patent/US9795644B2/en active Active
- 2010-06-07 LT LTEP16184996.3T patent/LT3141262T/lt unknown
- 2010-06-07 PL PL10724799T patent/PL2459217T3/pl unknown
- 2010-06-07 SI SI201031882T patent/SI3141262T1/sl unknown
- 2010-06-07 ES ES10724799.1T patent/ES2625977T3/es active Active
- 2010-06-07 WO PCT/EP2010/057935 patent/WO2010139809A1/en active Application Filing
- 2010-06-07 HU HUE10724799A patent/HUE033871T2/en unknown
- 2010-06-07 PT PT16184996T patent/PT3141262T/pt unknown
- 2010-06-07 HU HUE16184996A patent/HUE044107T2/hu unknown
- 2010-06-07 PT PT107247991T patent/PT2459217T/pt unknown
- 2010-06-07 DK DK16184996.3T patent/DK3141262T3/en active
- 2010-06-07 SI SI201031484A patent/SI2459217T1/sl unknown
- 2010-06-07 ES ES16184996T patent/ES2721752T3/es active Active
-
2017
- 2017-01-26 US US15/416,195 patent/US11027010B2/en active Active
- 2017-05-29 HR HRP20170799TT patent/HRP20170799T1/hr unknown
- 2017-06-08 CY CY20171100600T patent/CY1120484T1/el unknown
-
2019
- 2019-04-17 HR HRP20190736TT patent/HRP20190736T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20190736T1 (hr) | 2019-06-28 |
| EP3141262B1 (en) | 2019-01-23 |
| HRP20170799T1 (hr) | 2017-08-11 |
| LT3141262T (lt) | 2019-06-25 |
| SI2459217T1 (sl) | 2017-07-31 |
| US20170224810A1 (en) | 2017-08-10 |
| WO2010139809A1 (en) | 2010-12-09 |
| CA2764406C (en) | 2019-04-23 |
| DK2459217T3 (en) | 2017-05-22 |
| EP2258391A1 (en) | 2010-12-08 |
| PT3141262T (pt) | 2019-05-21 |
| SI3141262T1 (sl) | 2019-05-31 |
| EP2459217B1 (en) | 2017-04-12 |
| EP2459217A1 (en) | 2012-06-06 |
| HUE033871T2 (en) | 2018-01-29 |
| LT2459217T (lt) | 2017-06-26 |
| ES2625977T3 (es) | 2017-07-21 |
| CA2764406A1 (en) | 2010-12-09 |
| US20120148626A1 (en) | 2012-06-14 |
| HUE044107T2 (hu) | 2019-09-30 |
| AU2010255639A1 (en) | 2012-01-12 |
| US11027010B2 (en) | 2021-06-08 |
| CY1120484T1 (el) | 2019-07-10 |
| PL2459217T3 (pl) | 2017-09-29 |
| DK3141262T3 (en) | 2019-04-29 |
| US9795644B2 (en) | 2017-10-24 |
| PL3141262T3 (pl) | 2019-09-30 |
| EP3141262A1 (en) | 2017-03-15 |
| PT2459217T (pt) | 2017-07-14 |
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