BR112012030134A2 - processo para a produção de um extrato enriquecido de folhas de vitis vinifera l - Google Patents

processo para a produção de um extrato enriquecido de folhas de vitis vinifera l

Info

Publication number
BR112012030134A2
BR112012030134A2 BR112012030134A BR112012030134A BR112012030134A2 BR 112012030134 A2 BR112012030134 A2 BR 112012030134A2 BR 112012030134 A BR112012030134 A BR 112012030134A BR 112012030134 A BR112012030134 A BR 112012030134A BR 112012030134 A2 BR112012030134 A2 BR 112012030134A2
Authority
BR
Brazil
Prior art keywords
extract
vitis vinifera
production
water
leaves
Prior art date
Application number
BR112012030134A
Other languages
English (en)
Other versions
BR112012030134B1 (pt
Inventor
Bernd Plohmann
Bernd Walbroel
Bjoern Feistel
Martin Langer
Uwe Scheuring
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BR112012030134A2 publication Critical patent/BR112012030134A2/pt
Publication of BR112012030134B1 publication Critical patent/BR112012030134B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

processo para a produção de um extrato enriquecido de folhas de vitis vinifera l. a presente invenção refere-se a um processo para a produção de um extrato de folhas de vitis vinifera l. , compreendendo os seguintes estágios: a ) fornecimento de uma droga de folhas de vitis vinifera l., b) extração da droga com um eluente selecionado de áfua e misturas de água com álcool, obtendo um extrato bruto, c) separação do extrato bruto da droga extraída, d) remoção pelo menos parcial do eluente, obtendo um extrato espesso, e) redissolução do extrato espesso em água, f) separação dos componentes insolúveis, g) enriquecimento seletivo de ingredientes secundários da planta por meio de i. uma extração em duas fases ou ii. uma filtração por membranas; o extrato que pode ser obtido deste, preparações farmacêuticas contendo este extrato, bem como eu uso.
BR112012030134-9A 2010-05-28 2011-05-20 Processo para preparação de um extrato de folhas de vitis vinifera l BR112012030134B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10164316 2010-05-28
EP10164316.1 2010-05-28
PCT/EP2011/058282 WO2011147754A1 (de) 2010-05-28 2011-05-20 Verfahren zur herstellung eines angereicherten extraktes aus blättern von vitis vinifera l

Publications (2)

Publication Number Publication Date
BR112012030134A2 true BR112012030134A2 (pt) 2016-09-06
BR112012030134B1 BR112012030134B1 (pt) 2021-06-01

Family

ID=42335128

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012030134-9A BR112012030134B1 (pt) 2010-05-28 2011-05-20 Processo para preparação de um extrato de folhas de vitis vinifera l

Country Status (10)

Country Link
US (1) US20130210754A1 (pt)
EP (1) EP2575843B1 (pt)
JP (1) JP5979762B2 (pt)
BR (1) BR112012030134B1 (pt)
CA (1) CA2800758C (pt)
EA (1) EA022250B1 (pt)
ES (1) ES2663405T3 (pt)
MX (1) MX343308B (pt)
UA (1) UA109009C2 (pt)
WO (1) WO2011147754A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202014006415U1 (de) * 2014-08-12 2015-11-13 Boehringer Ingelheim International Gmbh Wasserlösliches Granulat zur Herstellung einer Trinklösung
CN112352943B (zh) * 2020-11-05 2022-06-14 浙江大学 从竹叶原料同步制备水溶性和油溶性竹叶抗氧化物的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL278161A (pt) 1961-05-13
IT1219732B (it) 1988-06-28 1990-05-24 Tecnofarmaci Spa Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono
CN1107110A (zh) 1993-10-19 1995-08-23 株式会社丰田自动织机制作所 幼儿用座
CN1043735C (zh) 1994-11-05 1999-06-23 李学军 蚂蚁制剂
US5912363A (en) * 1997-08-29 1999-06-15 Interhealth Nutraceuticals Method for extraction of proanthocyanidins from plant material
FR2795964A1 (fr) * 1999-07-08 2001-01-12 Actichem Procede de fabrication d'un extrait naturel de la vigne concentre en resveratrol et produits
JP2001122791A (ja) * 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤
US20020001651A1 (en) * 2000-01-24 2002-01-03 Norris Leslie Marie Method of altering and improving taste characteristics of edible consumables with monomeric or oligomeric polyphenolic compounds
US20040151787A1 (en) * 2002-11-21 2004-08-05 Pero Ronald W. Water soluble compositions derived from plant material and preparation thereof
CN1193995C (zh) 2003-05-30 2005-03-23 中国科学院新疆理化技术研究所 葡萄籽低聚原花青素的提取方法
ITAN20030053A1 (it) 2003-10-08 2005-04-09 Mauro Angeletti Processo per la produzione di estratto da semi d'uva a basso contenuto di polifenoli monomerici
WO2006001278A1 (ja) * 2004-06-28 2006-01-05 Kao Corporation Ａｍｐｋ活性化剤
ITMI20051485A1 (it) 2005-07-29 2007-01-30 Indena Spa Estratto da semi d'uva ottenibile per frazionamento su resina

Also Published As

Publication number Publication date
JP2013532134A (ja) 2013-08-15
EA022250B1 (ru) 2015-11-30
CA2800758C (en) 2018-04-24
BR112012030134B1 (pt) 2021-06-01
EA201201643A1 (ru) 2013-05-30
CA2800758A1 (en) 2011-12-01
EP2575843A1 (de) 2013-04-10
UA109009C2 (en) 2015-07-10
JP5979762B2 (ja) 2016-08-31
MX343308B (es) 2016-11-01
EP2575843B1 (de) 2017-03-01
WO2011147754A1 (de) 2011-12-01
ES2663405T3 (es) 2018-04-12
MX2012013678A (es) 2012-12-17
US20130210754A1 (en) 2013-08-15

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/05/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF