ES2721179T3 - Composiciones cosméticas y farmacéuticas a base de líquido de incubación de pescado - Google Patents

Composiciones cosméticas y farmacéuticas a base de líquido de incubación de pescado Download PDF

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Publication number
ES2721179T3
ES2721179T3 ES12813868T ES12813868T ES2721179T3 ES 2721179 T3 ES2721179 T3 ES 2721179T3 ES 12813868 T ES12813868 T ES 12813868T ES 12813868 T ES12813868 T ES 12813868T ES 2721179 T3 ES2721179 T3 ES 2721179T3
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Spain
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filter
filtrate
column
incubation liquid
collect
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ES12813868T
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English (en)
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Hans Kristian Leren
Fanny Fagot
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Aqua Bio Technology ASA
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Aqua Bio Technology ASA
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1706—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4806—Hydrolases (3) acting on peptide bonds (3.4) from animals other than mammals, e.g. snakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

Abstract

Un método para preparar una composición farmacéutica o cosmética de líquido de incubación de pescado que comprende al menos las etapas de: a) suspender huevos de pescado en un volumen mínimo de agua; b) inducir eclosión rápida, sincronizada, de dichos huevos, preferentemente de modo que la eclosión se complete en menos de 6 horas para más del 80 % de los embriones; c) opcionalmente filtrar los huevos eclosionados para obtener líquido de incubación; y d) filtrar el líquido de incubación usando un filtro con un tamaño de poro de al menos 5 μm y recoger el filtrado; e) someter el filtrado de la etapa (d) a cromatografía de intercambio iónico que comprende: (1) cargar el filtrado en una columna de intercambio iónico de DEAE (dietilaminoetilo); (2) lavar la columna con una solución de lavado tamponada a un pH de 7-9; (3) eluir los polipéptidos de leucolectina de la columna usando un primer tampón de elución que comprende la solución de lavado tamponada que comprende además una sal a una concentración de 50-100 mM; (4) eluir los polipéptidos restantes de la columna usando un segundo tampón de elución que comprende la solución de lavado tamponada que comprende una sal a una concentración de 500 mM a 2 M; (5) recoger el eluido de la etapa (4); f) cambiar el agua en el eluido de la etapa (5) con un tampón farmacéutica o cosméticamente aceptable realizando diafiltración usando un filtro con un tamaño de exclusión de menos de 12 kDa; g) filtrar la solución obtenida de la etapa (f) usando un filtro con un tamaño de poro de 0,15-0,30 μm y recoger el filtrado; y h) preparar dicha composición farmacéutica o cosmética del filtrado de la etapa (g).
ES12813868T 2012-12-21 2012-12-21 Composiciones cosméticas y farmacéuticas a base de líquido de incubación de pescado Active ES2721179T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/076853 WO2014094918A1 (en) 2012-12-21 2012-12-21 Cosmetic compositions from fish hatching fluid

Publications (1)

Publication Number Publication Date
ES2721179T3 true ES2721179T3 (es) 2019-07-29

Family

ID=47557107

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12813868T Active ES2721179T3 (es) 2012-12-21 2012-12-21 Composiciones cosméticas y farmacéuticas a base de líquido de incubación de pescado

Country Status (12)

Country Link
US (1) US10500255B2 (es)
EP (1) EP2934556B1 (es)
JP (1) JP6125036B2 (es)
KR (1) KR102134938B1 (es)
CN (1) CN105025906B (es)
AU (1) AU2012396934B2 (es)
BR (1) BR112015014532B1 (es)
CA (1) CA2895573C (es)
ES (1) ES2721179T3 (es)
HK (1) HK1210014A1 (es)
RU (1) RU2611639C2 (es)
WO (1) WO2014094918A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0819883D0 (en) * 2008-10-29 2008-12-03 Azyme Res As Product and uses
EP2691069B1 (en) 2012-01-23 2016-09-28 Restorsea, LLC Cosmetic
GB201223330D0 (en) * 2012-12-21 2013-02-06 Aqua Bio Technology Asa Products, methods and uses
JP6089152B2 (ja) 2013-12-13 2017-03-01 レスターシー エルエルシイＲｅｓｔｏｒｓｅａ， Ｌｌｃ 剥脱性の毛髪保持促進製剤
AU2015259509A1 (en) 2014-05-16 2016-11-24 Restorsea, Llc Biphasic cosmetic
CN105301169A (zh) * 2015-12-09 2016-02-03 河南省奥林特药业有限公司 利用薄层色谱法鉴别甜地丁真伪的方法
MA44737A (fr) * 2016-04-19 2021-04-07 Azura Ophthalmics Ltd Compositions pour le traitement de troubles liés à l'hyperkératose
RU2677661C1 (ru) * 2017-11-30 2019-01-18 Общество с ограниченной ответственностью "Химико-биологическое объединение при РАН "Фирма "ВИТА" Активная косметическая добавка
CA3146128A1 (en) * 2019-07-05 2021-01-14 Regenics As Wound debridement systems
JP2023510499A (ja) 2020-01-10 2023-03-14 アズーラ オフサルミックス エルティーディー． 組成物および過敏症のための指示

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268499A (en) 1979-06-07 1981-05-19 Dow Corning Corporation Antiperspirant emulsion compositions
NO314594B1 (no) * 1997-12-11 2003-04-14 Aqua Bio Technology As Ikke-selvdegraderende endoprotease, fremgangsmåte for fremstilling samt anvendelser av denne
GB9918023D0 (en) * 1999-07-30 1999-09-29 Unilever Plc Skin care composition
TWI318881B (es) * 2001-09-27 2010-01-01
US20080131493A1 (en) 2004-01-02 2008-06-05 Haitham Matloub Method and Multilayered Device for Controlled Topical Delivery of Therapeutic Agents to the Skin
US7316817B2 (en) 2004-01-02 2008-01-08 New Medical Technologies, Inc. Method and device for topical delivery of therapeutic agents to the skin
DE102005053909A1 (de) 2005-05-13 2006-11-16 Beiersdorf Ag Selbstklebende Hautauflage und Kombinationsset zur kosmetischen Hautpflege
JP5243792B2 (ja) 2005-06-01 2013-07-24 ニプロパッチ株式会社 貼付剤
US8075920B2 (en) * 2006-05-11 2011-12-13 Regenics A/S Administration of cells and cellular extracts for rejuvenation
GB0819883D0 (en) * 2008-10-29 2008-12-03 Azyme Res As Product and uses
GB0921001D0 (en) * 2009-11-30 2010-01-13 Aqua Bio Technology Asa Products and uses

Also Published As

Publication number Publication date
CA2895573A1 (en) 2014-06-26
RU2015127472A (ru) 2017-01-25
CN105025906B (zh) 2020-08-25
AU2012396934A1 (en) 2015-07-16
CA2895573C (en) 2021-01-12
KR102134938B1 (ko) 2020-07-17
CN105025906A (zh) 2015-11-04
EP2934556B1 (en) 2019-03-27
KR20150096800A (ko) 2015-08-25
HK1210014A1 (en) 2016-04-15
BR112015014532B1 (pt) 2021-08-24
US20150328290A1 (en) 2015-11-19
EP2934556A1 (en) 2015-10-28
WO2014094918A1 (en) 2014-06-26
BR112015014532A2 (pt) 2017-10-10
AU2012396934B2 (en) 2018-08-09
JP2016510312A (ja) 2016-04-07
RU2611639C2 (ru) 2017-02-28
JP6125036B2 (ja) 2017-05-10
US10500255B2 (en) 2019-12-10

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