ES2710313R1 - Composicion para la prevencion de la trombogenesis y procedimiento para fabricacion de la misma - Google Patents

Composicion para la prevencion de la trombogenesis y procedimiento para fabricacion de la misma

Info

Publication number
ES2710313R1
ES2710313R1 ES201790037A ES201790037A ES2710313R1 ES 2710313 R1 ES2710313 R1 ES 2710313R1 ES 201790037 A ES201790037 A ES 201790037A ES 201790037 A ES201790037 A ES 201790037A ES 2710313 R1 ES2710313 R1 ES 2710313R1
Authority
ES
Spain
Prior art keywords
thrombogenesis
prevention
procedure
manufacturing
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201790037A
Other languages
English (en)
Other versions
ES2710313A2 (es
ES2710313B1 (es
Inventor
Leslie Roy Berry
Attilio Difiore
Anthony Kam Chuen Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Attwill Medical Solutions Inc
Original Assignee
Attwill Medical Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Attwill Medical Solutions Inc filed Critical Attwill Medical Solutions Inc
Publication of ES2710313A2 publication Critical patent/ES2710313A2/es
Publication of ES2710313R1 publication Critical patent/ES2710313R1/es
Application granted granted Critical
Publication of ES2710313B1 publication Critical patent/ES2710313B1/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ES201790037A 2015-04-15 2016-04-15 Composicion para la prevencion de la trombogenesis y procedimiento para fabricacion de la misma Active ES2710313B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562148112P 2015-04-15 2015-04-15
PCT/US2016/027905 WO2016168710A1 (en) 2015-04-15 2016-04-15 Antithrombin-heparin compositions and methods

Publications (3)

Publication Number Publication Date
ES2710313A2 ES2710313A2 (es) 2019-04-24
ES2710313R1 true ES2710313R1 (es) 2019-07-02
ES2710313B1 ES2710313B1 (es) 2020-04-07

Family

ID=57126920

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201790037A Active ES2710313B1 (es) 2015-04-15 2016-04-15 Composicion para la prevencion de la trombogenesis y procedimiento para fabricacion de la misma

Country Status (7)

Country Link
US (2) US20170020911A1 (es)
JP (1) JP2018513217A (es)
AU (1) AU2016249391A1 (es)
CA (1) CA2982832A1 (es)
ES (1) ES2710313B1 (es)
GB (1) GB2554296A (es)
WO (1) WO2016168710A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
WO2013009998A2 (en) 2011-07-12 2013-01-17 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into trans-dermal catheter
CA2945406C (en) 2014-05-02 2022-10-18 Excelsior Medical Corporation Strip package for antiseptic cap
CA2982456A1 (en) 2015-05-08 2016-11-17 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
ES2929769T3 (es) 2016-10-14 2022-12-01 Icu Medical Inc Tapas desinfectantes para conectores médicos
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
CA3118905A1 (en) 2018-11-21 2020-05-28 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
WO2022125474A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods
US20240181024A1 (en) * 2021-03-26 2024-06-06 Ath Therapeutics Inc. Treating respiratory infections

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124705A1 (en) * 1995-11-30 2003-07-03 Berry Leslie Roy Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0714412A1 (en) * 1993-08-19 1996-06-05 Minnesota Mining And Manufacturing Company Heparin functional affinity supports
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124705A1 (en) * 1995-11-30 2003-07-03 Berry Leslie Roy Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Andersson L O et al. ANTICOAGULANT PROPERTIES OF HEPARIN FRACTIONATED BY AFFINITY CHROMATOGRAPHY ON MATRIX-BOUND ANTITHROMBIN III AND BY GEL FILTRATION. THROMBOSIS RESEARCH, 19761201 TARRYTOWN, NY, US. Brenner Benjamin; Greer Ian A; Monreal Manuel, 01/12/1976, Vol. 9, Nº 6, Páginas 575 - 583 ISSN 0049-3848, todo el documento. *
Yoshimura J et al. ON THE CATALYSIS OF THE AMADORI REARRANGEMENT. CARBOHYDRATE RESEARCH PERGAMON, GB. Lowary Todd, 1969, Vol. 11, Nº 2, Páginas 276 - 281 ISSN 0008-6215, (DOI: doi:10.1016/S0008-6215(00)80087-7) Página 276; figura 2. *

Also Published As

Publication number Publication date
GB2554296A (en) 2018-03-28
ES2710313A2 (es) 2019-04-24
JP2018513217A (ja) 2018-05-24
WO2016168710A1 (en) 2016-10-20
AU2016249391A1 (en) 2017-12-07
US20170020911A1 (en) 2017-01-26
CA2982832A1 (en) 2016-10-20
US20190030066A1 (en) 2019-01-31
GB201718876D0 (en) 2017-12-27
ES2710313B1 (es) 2020-04-07

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