ES268769A1 - Procedimiento para la preparaciën de nuevos derivados de la tetrahidro-5,10,11,12 dibenzo [b,g] azocina - Google Patents
Procedimiento para la preparaciën de nuevos derivados de la tetrahidro-5,10,11,12 dibenzo [b,g] azocinaInfo
- Publication number
- ES268769A1 ES268769A1 ES0268769A ES268769A ES268769A1 ES 268769 A1 ES268769 A1 ES 268769A1 ES 0268769 A ES0268769 A ES 0268769A ES 268769 A ES268769 A ES 268769A ES 268769 A1 ES268769 A1 ES 268769A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- compound
- piperazino
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004931 azocinyl group Chemical class N1=C(C=CC=CC=C1)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 13
- -1 monoalkylamino Chemical group 0.000 abstract 10
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- MZRVEZGGRBJDDB-UHFFFAOYSA-N N-Butyllithium Chemical compound [Li]CCCC MZRVEZGGRBJDDB-UHFFFAOYSA-N 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 2
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ALTICNLJGXVIKF-UHFFFAOYSA-N (3-chloro-2-methylpropyl) 4-methylbenzenesulfonate Chemical compound ClCC(COS(=O)(=O)C1=CC=C(C=C1)C)C ALTICNLJGXVIKF-UHFFFAOYSA-N 0.000 abstract 1
- AAQRCUVXXKRPGZ-UHFFFAOYSA-N 12-(3-chloro-2-methylpropyl)-5,6,7,12-tetrahydrobenzo[b][1]benzazocine Chemical compound ClCC(CC1C2=C(NC3=C(C=C1)C=CCC3)C=CC=C2)C AAQRCUVXXKRPGZ-UHFFFAOYSA-N 0.000 abstract 1
- YOTOXGNLRUJVPG-UHFFFAOYSA-N 12-(3-chloropropyl)-5,6,7,12-tetrahydrobenzo[b][1]benzazocine Chemical compound ClCCCC1C2=C(NC3=C(C=C1)C=CCC3)C=CC=C2 YOTOXGNLRUJVPG-UHFFFAOYSA-N 0.000 abstract 1
- ZYWWKZBZFUBCTJ-UHFFFAOYSA-N 2-(5,6,7,12-tetrahydrobenzo[b][1]benzazocin-12-yl)ethanol Chemical compound OCCC1C2=C(NC3=C(C=C1)C=CCC3)C=CC=C2 ZYWWKZBZFUBCTJ-UHFFFAOYSA-N 0.000 abstract 1
- YTAIXXIZFSNGCS-UHFFFAOYSA-N 5,6,7,12-tetrahydrobenzo[b][1]benzazocine Chemical compound C1=CC=CC2=C1NC1=C(C=CC2)C=CCC1 YTAIXXIZFSNGCS-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 229940125683 antiemetic agent Drugs 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/08—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with two six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR832058A FR1403603A (fr) | 1960-07-05 | 1960-07-05 | Nouveaux dérivés de la tétrahydro-5, 10, 11, 12 dibenz [b, g] azocine et leurs procédés de préparation |
| FR863626A FR1339M (fr) | 1960-07-05 | 1961-06-01 | Dérivés de la dibenzazocine. |
| FR863760A FR85301E (fr) | 1960-07-05 | 1961-06-02 | Nouveaux dérivés de la tétrahydro-5, 10, 11, 12 dibenzo [b, g] azocine et leurs procédés de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES268769A1 true ES268769A1 (es) | 1961-12-16 |
Family
ID=39275492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0268769A Expired ES268769A1 (es) | 1960-07-05 | 1961-07-04 | Procedimiento para la preparaciën de nuevos derivados de la tetrahidro-5,10,11,12 dibenzo [b,g] azocina |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE605628A (en:Method) |
| CH (2) | CH439300A (en:Method) |
| DE (1) | DE1180751B (en:Method) |
| ES (1) | ES268769A1 (en:Method) |
| FR (3) | FR1403603A (en:Method) |
| GB (1) | GB983859A (en:Method) |
| LU (1) | LU40250A1 (en:Method) |
| NL (1) | NL113370C (en:Method) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT196879B (de) * | 1955-10-26 | 1958-03-25 | Rhone Poulenc Sa | Verfahren zur Herstellung von neuen Derivaten des Iminodibenzyls |
-
0
- NL NL113370D patent/NL113370C/xx active
-
1960
- 1960-07-05 FR FR832058A patent/FR1403603A/fr not_active Expired
-
1961
- 1961-06-01 FR FR863626A patent/FR1339M/fr not_active Expired
- 1961-06-02 FR FR863760A patent/FR85301E/fr not_active Expired
- 1961-06-13 LU LU40250D patent/LU40250A1/xx unknown
- 1961-06-30 BE BE605628A patent/BE605628A/fr unknown
- 1961-07-03 GB GB2402461A patent/GB983859A/en not_active Expired
- 1961-07-04 CH CH1582965A patent/CH439300A/fr unknown
- 1961-07-04 ES ES0268769A patent/ES268769A1/es not_active Expired
- 1961-07-04 CH CH782861A patent/CH422795A/fr unknown
- 1961-07-05 DE DES74667A patent/DE1180751B/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH439300A (fr) | 1967-07-15 |
| LU40250A1 (en:Method) | 1961-08-14 |
| FR1339M (fr) | 1962-06-04 |
| CH422795A (fr) | 1966-10-31 |
| FR1403603A (fr) | 1965-06-25 |
| FR85301E (fr) | 1965-07-23 |
| BE605628A (fr) | 1962-01-02 |
| NL113370C (en:Method) | |
| GB983859A (en) | 1965-02-17 |
| DE1180751B (de) | 1964-11-05 |
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