ES2686909B1 - Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas - Google Patents
Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas Download PDFInfo
- Publication number
- ES2686909B1 ES2686909B1 ES201730399A ES201730399A ES2686909B1 ES 2686909 B1 ES2686909 B1 ES 2686909B1 ES 201730399 A ES201730399 A ES 201730399A ES 201730399 A ES201730399 A ES 201730399A ES 2686909 B1 ES2686909 B1 ES 2686909B1
- Authority
- ES
- Spain
- Prior art keywords
- cdc
- treatment
- inhibiting compounds
- neurological pathologies
- pathologies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201730399A ES2686909B1 (es) | 2017-03-22 | 2017-03-22 | Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas |
US16/495,613 US11446304B2 (en) | 2017-03-22 | 2018-03-21 | CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions |
AU2018240527A AU2018240527B2 (en) | 2017-03-22 | 2018-03-21 | CDC-7-inhibitor compounds and use thereof for the treatment of neurological conditions |
PCT/ES2018/070215 WO2018172587A1 (es) | 2017-03-22 | 2018-03-21 | Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologías neurológicas |
EP18771997.6A EP3604310A4 (en) | 2017-03-22 | 2018-03-21 | CDC-7 INHIBITOR COMPOUNDS AND USE THEREOF IN THE TREATMENT OF NEUROLOGICAL DISEASES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201730399A ES2686909B1 (es) | 2017-03-22 | 2017-03-22 | Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2686909A1 ES2686909A1 (es) | 2018-10-22 |
ES2686909B1 true ES2686909B1 (es) | 2019-08-16 |
Family
ID=63584204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES201730399A Active ES2686909B1 (es) | 2017-03-22 | 2017-03-22 | Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas |
Country Status (5)
Country | Link |
---|---|
US (1) | US11446304B2 (es) |
EP (1) | EP3604310A4 (es) |
AU (1) | AU2018240527B2 (es) |
ES (1) | ES2686909B1 (es) |
WO (1) | WO2018172587A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2749743B2 (es) * | 2018-09-21 | 2020-12-14 | Consejo Superior Investigacion | Derivados de purina inhibidores de cdc7 y su uso para el tratamiento de patologias neurologicas |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3232937A (en) * | 1962-08-02 | 1966-02-01 | Burroughs Wellcome Co | 6-benzylmercaptopurines |
EA000072B1 (ru) | 1995-11-14 | 1998-06-25 | Фармация Энд Апджон С.П.А. | Бициклическое конденсированное пиримидиновое соединение и его применение в качестве терапевтического агента |
EP1352910A1 (en) * | 2002-04-10 | 2003-10-15 | Grünenthal GmbH | New analogs of nitrobenzylthioinosine |
JP2004161716A (ja) * | 2002-11-15 | 2004-06-10 | Takeda Chem Ind Ltd | Jnk阻害剤 |
EP1444982A1 (de) * | 2003-02-06 | 2004-08-11 | Merckle Gmbh | Verwendung von Purinderivaten als selektive Kinase-Inhibitoren |
KR20080110912A (ko) | 2006-04-19 | 2008-12-19 | 노파르티스 아게 | 인다졸 화합물 및 cdc7의 억제 방법 |
EP2365810A2 (en) | 2008-12-04 | 2011-09-21 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of cns disorders |
CA2767091A1 (en) | 2009-07-15 | 2011-01-20 | Abbott Laboratories | Pyrrolopyrazine inhibitors of kinases |
US20130072506A1 (en) | 2011-09-16 | 2013-03-21 | Lenka ZAHAJSKA | 6,8-disubstituted purine compositions |
-
2017
- 2017-03-22 ES ES201730399A patent/ES2686909B1/es active Active
-
2018
- 2018-03-21 EP EP18771997.6A patent/EP3604310A4/en active Pending
- 2018-03-21 US US16/495,613 patent/US11446304B2/en active Active
- 2018-03-21 AU AU2018240527A patent/AU2018240527B2/en active Active
- 2018-03-21 WO PCT/ES2018/070215 patent/WO2018172587A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2018240527A1 (en) | 2019-11-07 |
US20200093828A1 (en) | 2020-03-26 |
ES2686909A1 (es) | 2018-10-22 |
AU2018240527B2 (en) | 2022-05-19 |
EP3604310A4 (en) | 2020-09-02 |
WO2018172587A1 (es) | 2018-09-27 |
EP3604310A1 (en) | 2020-02-05 |
US11446304B2 (en) | 2022-09-20 |
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Legal Events
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BA2A | Patent application published |
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