ES259514A1 - Procedimiento para la isomerizaciën de compuestos triciclicos - Google Patents

Procedimiento para la isomerizaciën de compuestos triciclicos

Info

Publication number
ES259514A1
ES259514A1 ES0259514A ES259514A ES259514A1 ES 259514 A1 ES259514 A1 ES 259514A1 ES 0259514 A ES0259514 A ES 0259514A ES 259514 A ES259514 A ES 259514A ES 259514 A1 ES259514 A1 ES 259514A1
Authority
ES
Spain
Prior art keywords
isomer
oxalic acid
mixture
hydroxy
thioxanthene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0259514A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH7509159A external-priority patent/CH387655A/de
Priority claimed from CH7558059A external-priority patent/CH393358A/de
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES259514A1 publication Critical patent/ES259514A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la isomerización de compuestos tricíclicosel cual comprende el tratar un isómeroo una mezcla de isómeros correspondientes que contengan uno de los isómeros en exceso sobre el otrode un compuesto de la fórmula general **(Ver fórmula)** en la cual X representa oxígeno o azufre e Y representa un grupo amino terciariocompuesto que está substituído asimétricamente por tener por lo menos un substituyentes nuclear aromático escogido en el grupo compuesto por alquilotrifluorometiloaralquiloariloalcoxiaralcoxiariloxialquiltioaralquiltioariltiohalógenoaciloaminohidroxilo y carbonilocon un reactivo ácido ysi se deseael convertir en la base libre la sal obtenida.
ES0259514A 1959-06-30 1960-06-28 Procedimiento para la isomerizaciën de compuestos triciclicos Expired ES259514A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH7509159A CH387655A (de) 1959-06-30 1959-06-30 Verfahren zur Isomerisierung von tricyclischen Verbindungen
CH7558059A CH393358A (de) 1959-07-10 1959-07-10 Verfahren zur Isomerisierung von tricyclischen Verbindungen
CH7973059A CH410002A (de) 1959-06-30 1959-10-22 Verfahren zur cis-/trans-Isomerisierung von tricyclischen Verbindungen

Publications (1)

Publication Number Publication Date
ES259514A1 true ES259514A1 (es) 1961-01-16

Family

ID=27178565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0259514A Expired ES259514A1 (es) 1959-06-30 1960-06-28 Procedimiento para la isomerizaciën de compuestos triciclicos

Country Status (7)

Country Link
US (1) US3113137A (es)
BE (1) BE592122A (es)
CH (1) CH410002A (es)
CS (1) CS152990B2 (es)
ES (1) ES259514A1 (es)
GB (1) GB899898A (es)
OA (1) OA00955A (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192204A (en) * 1960-03-07 1965-06-29 Smith Kline French Lab Trifluoromethylthiaxanthene and -xanthene derivatives
GB1013901A (en) * 1962-01-26 1965-12-22 Kefalas As Dihydroanthracene, dibenzocycloheptadiene and dibenzocycloheptatriene derivatives
US3609167A (en) * 1962-04-02 1971-09-28 Smith Kline French Lab IBENZO{8 b,e{9 {0 THIEPINES
US3282930A (en) * 1962-08-17 1966-11-01 Smith Kline French Lab Hydroxyalkylenepiperazine derivatives and analogs thereof
US3310553A (en) * 1962-09-25 1967-03-21 Pfizer & Co C Alkylated thioxathenesulfonamides
US3282936A (en) * 1963-05-01 1966-11-01 Geigy Chem Corp Process for the conversion of cis-2-phenyl-3-methylmorpholine to trans-2-phenyl-3-methylmorpholine
US3248291A (en) * 1963-08-19 1966-04-26 Hoffmann La Roche Stabilized thioxanthene derivatives and method of using the same
US3337407A (en) * 1965-02-24 1967-08-22 Merck & Co Inc Uricosuric agent
US3681346A (en) * 1969-06-20 1972-08-01 Kefalas As {60 -isomer of the decanoic acid ester of 10-{8 3,-(4-hydroxyethyl-1-piperazinyl)propylidene{9 -2-trifluoro-methyl thiaxanthene, acid addition salts thereof, method of use and compositions
GB1469108A (en) * 1973-06-25 1977-03-30 Kefalas As Thiaxanthene derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2957880A (en) * 1953-12-23 1960-10-25 Ciba Pharm Prod Inc Process for the conversion of stereoisomers
US2996503A (en) * 1955-09-23 1961-08-15 Merck & Co Inc Derivatives of heterocyclic compounds
DE1044103B (de) * 1956-06-12 1958-11-20 Hoffmann La Roche Verfahren zur Herstellung von Xanthen- bzw. Thioxanthenderivaten
BE557002A (es) * 1956-07-09
BE568611A (es) * 1957-07-18

Also Published As

Publication number Publication date
OA00955A (fr) 1968-03-22
GB899898A (en) 1962-06-27
US3113137A (en) 1963-12-03
CH410002A (de) 1966-03-31
CS152990B2 (es) 1974-02-22
BE592122A (fr) 1960-12-21

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