ES2570559T3 - Método para determinar la propensión a la calcificación - Google Patents

Método para determinar la propensión a la calcificación

Info

Publication number
ES2570559T3
ES2570559T3 ES12783589T ES12783589T ES2570559T3 ES 2570559 T3 ES2570559 T3 ES 2570559T3 ES 12783589 T ES12783589 T ES 12783589T ES 12783589 T ES12783589 T ES 12783589T ES 2570559 T3 ES2570559 T3 ES 2570559T3
Authority
ES
Spain
Prior art keywords
pcp
calcification
propensity
iii
primary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12783589T
Other languages
English (en)
Inventor
Wilhelm Jahnen-Dechent
Andreas Pasch
Stefan Farese
Steffen Gräber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rheinisch Westlische Technische Hochschuke RWTH
Original Assignee
Rheinisch Westlische Technische Hochschuke RWTH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheinisch Westlische Technische Hochschuke RWTH filed Critical Rheinisch Westlische Technische Hochschuke RWTH
Application granted granted Critical
Publication of ES2570559T3 publication Critical patent/ES2570559T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4707—Forward scatter; Low angle scatter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/107—Crystal induced conditions; Gout
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Método para determinar la propensión de un fluido a la calcificación, en el que dicho método se caracteriza por las siguientes etapas: (i) añadir una sal de calcio soluble y una sal de fosfato soluble a una muestra de dicho fluido; (ii) incubar dicha muestras en condiciones que permiten la formación de partículas de calciproteína (PCP); y (iii) determinar una o más de las siguientes: (a) la tasa de formación de PCP primarias y/o secundarias; (b) la cantidad de PCP primarias y/o secundarias; y/o (c) la tasa de transición de PCP primarias a PCP secundarias, en el que un aumento en una o más de (a), (b) y/o (c) de la etapa (iii) indica una propensión aumentada de dicho fluido a la calcificación, y en el que una o más de (a), (b) y/o (c) de la etapa (iii) se compara(n) con una o más muestra(s) de control.
ES12783589T 2011-11-07 2012-11-07 Método para determinar la propensión a la calcificación Active ES2570559T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11008849.9A EP2589964A1 (en) 2011-11-07 2011-11-07 A method for determining the propensity for calcification
PCT/EP2012/071971 WO2013068372A1 (en) 2011-11-07 2012-11-07 A method for determining the propensity for calcification

Publications (1)

Publication Number Publication Date
ES2570559T3 true ES2570559T3 (es) 2016-05-19

Family

ID=47146392

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12783589T Active ES2570559T3 (es) 2011-11-07 2012-11-07 Método para determinar la propensión a la calcificación

Country Status (15)

Country Link
US (2) US9651566B2 (es)
EP (3) EP2589964A1 (es)
JP (1) JP6104265B2 (es)
KR (1) KR101978346B1 (es)
CN (1) CN103930788B (es)
AU (1) AU2012334149B2 (es)
BR (1) BR112014010869B1 (es)
CA (1) CA2854587C (es)
DK (1) DK3002590T3 (es)
ES (1) ES2570559T3 (es)
HK (1) HK1202332A1 (es)
IL (1) IL232355A0 (es)
NO (1) NO3002590T3 (es)
PT (1) PT3002590T (es)
WO (1) WO2013068372A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2589964A1 (en) * 2011-11-07 2013-05-08 Rheinisch-Westfälisch-Technische Hochschule Aachen A method for determining the propensity for calcification
JP6566697B2 (ja) * 2015-04-08 2019-08-28 学校法人自治医科大学 蛍光プローブを用いた新規カルシプロテイン粒子（ｃｐｐ）測定法
CN109562352B (zh) * 2016-08-01 2021-12-28 株式会社钟化 钙蛋白粒子的吸附材料以及吸附除去系统及其利用方法
JP6877769B2 (ja) 2016-08-31 2021-05-26 国立大学法人東海国立大学機構 ホスホール化合物
WO2020191347A1 (en) * 2019-03-21 2020-09-24 Dawatek, Llc Offset raman imaging system and methods of use
CN109966780B (zh) * 2019-03-21 2021-03-09 浙江工商大学 一种水生贝类蒸煮汤中功能性纳米颗粒的分离方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0972891A (ja) * 1994-07-07 1997-03-18 Hitachi Koki Co Ltd 等密度分子の分離法
AU2756701A (en) * 2000-01-04 2001-07-16 Regents Of The University Of California, The Use of low dosage bisphosphonates to inhibit cardiac and arterial calcification
JP2002139501A (ja) 2000-10-30 2002-05-17 Mass Medical Kk リポ蛋白サブクラスの分析ならびに診断方法
WO2005046455A2 (en) * 2003-11-12 2005-05-26 Ping Gao Methods for identifying or monitoring a patient with increased risk of cardiovascular calcification
GB201002382D0 (en) * 2010-02-12 2010-03-31 King S College London Assay
EP2589964A1 (en) * 2011-11-07 2013-05-08 Rheinisch-Westfälisch-Technische Hochschule Aachen A method for determining the propensity for calcification

Also Published As

Publication number Publication date
WO2013068372A1 (en) 2013-05-16
PT3002590T (pt) 2017-12-06
JP2014535054A (ja) 2014-12-25
KR101978346B1 (ko) 2019-05-14
BR112014010869A2 (pt) 2017-06-13
AU2012334149B2 (en) 2017-08-10
KR20140090246A (ko) 2014-07-16
CN103930788B (zh) 2016-09-14
US10054601B2 (en) 2018-08-21
CA2854587C (en) 2019-12-03
IL232355A0 (en) 2014-06-30
CA2854587A1 (en) 2013-05-16
BR112014010869B1 (pt) 2021-07-06
EP2589964A1 (en) 2013-05-08
US9651566B2 (en) 2017-05-16
EP2776840A1 (en) 2014-09-17
BR112014010869A8 (pt) 2017-06-20
NO3002590T3 (es) 2018-02-03
EP3002590B1 (en) 2017-09-06
EP2776840B1 (en) 2016-02-03
US20170292962A1 (en) 2017-10-12
AU2012334149A1 (en) 2014-04-24
JP6104265B2 (ja) 2017-03-29
HK1202332A1 (zh) 2015-09-25
DK3002590T3 (da) 2017-11-27
EP3002590A1 (en) 2016-04-06
CN103930788A (zh) 2014-07-16
US20140377874A1 (en) 2014-12-25

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