ES255380A1 - Process for the production of a derivative of hypoglycine a - Google Patents

Process for the production of a derivative of hypoglycine a

Info

Publication number
ES255380A1
ES255380A1 ES0255380A ES255380A ES255380A1 ES 255380 A1 ES255380 A1 ES 255380A1 ES 0255380 A ES0255380 A ES 0255380A ES 255380 A ES255380 A ES 255380A ES 255380 A1 ES255380 A1 ES 255380A1
Authority
ES
Spain
Prior art keywords
compound
formula
reacting
hypoglycine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0255380A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES255380A1 publication Critical patent/ES255380A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises a compound of the formula <FORM:0921556/IV(a)/1> and the preparation thereof by reacting a compound of the formula <FORM:0921556/IV(a)/2> (wherein R is an alkyl group in an inert anhydrous organic solvent and in the presence of a tertiary organic base, with a halogen formic acid alkyl or aralkyl ester, reacting the solution of a mixed anhydride so obtained with an aqueous solution of an alkali metal salt of a compound of the formula <FORM:0921556/IV(a)/3> to give a compound of the formula <FORM:0921556/IV(a)/4> and hydrolysing this under alkaline conditions. All the steps in the reaction are performed at low temperatures. An example is given.
ES0255380A 1959-01-30 1960-01-29 Process for the production of a derivative of hypoglycine a Expired ES255380A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH6901059 1959-01-30

Publications (1)

Publication Number Publication Date
ES255380A1 true ES255380A1 (en) 1960-07-01

Family

ID=4529164

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0255380A Expired ES255380A1 (en) 1959-01-30 1960-01-29 Process for the production of a derivative of hypoglycine a

Country Status (2)

Country Link
ES (1) ES255380A1 (en)
GB (1) GB921556A (en)

Also Published As

Publication number Publication date
GB921556A (en) 1963-03-20

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