ES2534055T9 - Opioides de amina no fenólicos con sustituyentes de gran tamaño - Google Patents
Opioides de amina no fenólicos con sustituyentes de gran tamañoInfo
- Publication number
- ES2534055T9 ES2534055T9 ES09790652T ES09790652T ES2534055T9 ES 2534055 T9 ES2534055 T9 ES 2534055T9 ES 09790652 T ES09790652 T ES 09790652T ES 09790652 T ES09790652 T ES 09790652T ES 2534055 T9 ES2534055 T9 ES 2534055T9
- Authority
- ES
- Spain
- Prior art keywords
- opioids
- phenolic amine
- large substituents
- substituents
- phenolic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8225508P | 2008-07-21 | 2008-07-21 | |
| US82255P | 2008-07-21 | ||
| PCT/US2009/051200 WO2010011619A1 (en) | 2008-07-21 | 2009-07-21 | Large substituent, non-phenolic amine opioids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2534055T3 ES2534055T3 (es) | 2015-04-16 |
| ES2534055T9 true ES2534055T9 (es) | 2016-05-31 |
Family
ID=41137538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09790652.3T Active ES2534055T3 (es) | 2008-07-21 | 2009-07-21 | Opioides de amina no fenólicos con sustituyentes de gran tamaño |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100190817A1 (es) |
| EP (1) | EP2318372B9 (es) |
| JP (2) | JP5727374B2 (es) |
| AU (1) | AU2009274147B2 (es) |
| CA (1) | CA2731429C (es) |
| ES (1) | ES2534055T3 (es) |
| WO (1) | WO2010011619A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2318372B9 (en) * | 2008-07-21 | 2015-05-06 | Rensselaer Polytechnic Institute | Large substituent, non-phenolic amine opioids |
| AU2010326676B2 (en) | 2009-12-04 | 2013-03-14 | Alkermes Pharma Ireland Limited | Morphinan derivatives for the treatment of drug overdose |
| JP5964809B2 (ja) | 2010-03-22 | 2016-08-03 | レンセラール ポリテクニック インスティチュート | オピオイド受容体リガンドとしてのカルボキサミド基を含有するモルヒネ誘導体 |
| FI3446565T3 (fi) | 2010-08-23 | 2024-01-30 | Alkermes Pharma Ireland Ltd | Menetelmiä antipsykoottisten lääkkeiden aiheuttaman painonnousun hoitamiseksi |
| JP5981992B2 (ja) * | 2011-06-29 | 2016-08-31 | アルカーメス，インコーポレイテッド | 末梢作用オピオイド化合物 |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| US9656961B2 (en) | 2013-05-24 | 2017-05-23 | Alkermes Pharma Ireland Limited | Methods for treating depressive symptoms |
| EP3004114B1 (en) | 2013-05-24 | 2019-12-25 | Alkermes Pharma Ireland Limited | Morphan and morphinan analogues, and methods of use |
| EP4243768A1 (en) | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002036573A2 (en) * | 2000-10-31 | 2002-05-10 | Rensselaer Polytechnic Institute | 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents |
| AU2003281060A1 (en) * | 2002-07-16 | 2004-02-02 | Rensselaer Polytechnic Institute | Process for conversion of phenols to carboxamides via the succinimide esters |
| CA2615774C (en) * | 2005-07-21 | 2014-12-09 | Rensselaer Polytechnic Institute | Large substituent, non-phenolic opioids |
| EP2318372B9 (en) * | 2008-07-21 | 2015-05-06 | Rensselaer Polytechnic Institute | Large substituent, non-phenolic amine opioids |
-
2009
- 2009-07-21 EP EP20090790652 patent/EP2318372B9/en active Active
- 2009-07-21 CA CA2731429A patent/CA2731429C/en active Active
- 2009-07-21 JP JP2011520127A patent/JP5727374B2/ja active Active
- 2009-07-21 US US12/506,354 patent/US20100190817A1/en not_active Abandoned
- 2009-07-21 ES ES09790652.3T patent/ES2534055T3/es active Active
- 2009-07-21 AU AU2009274147A patent/AU2009274147B2/en active Active
- 2009-07-21 WO PCT/US2009/051200 patent/WO2010011619A1/en active Application Filing
-
2014
- 2014-10-03 JP JP2014204620A patent/JP2015044819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011528718A (ja) | 2011-11-24 |
| CA2731429C (en) | 2016-12-13 |
| AU2009274147B2 (en) | 2014-09-04 |
| EP2318372A1 (en) | 2011-05-11 |
| CA2731429A1 (en) | 2010-01-28 |
| AU2009274147A1 (en) | 2010-01-28 |
| EP2318372B9 (en) | 2015-05-06 |
| WO2010011619A1 (en) | 2010-01-28 |
| JP2015044819A (ja) | 2015-03-12 |
| US20100190817A1 (en) | 2010-07-29 |
| JP5727374B2 (ja) | 2015-06-03 |
| ES2534055T3 (es) | 2015-04-16 |
| EP2318372B1 (en) | 2015-01-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2534055T9 (es) | Opioides de amina no fenólicos con sustituyentes de gran tamaño | |
| BRPI0918760A2 (pt) | compostos morfinanos | |
| BRPI0911989A2 (pt) | uniões micélicas | |
| BRPI0913381A2 (pt) | sistema de injeção multiponto para operações de campo petrolífero | |
| ATE542825T1 (de) | Substituierte piperidino-dihydrothienopyrimidine | |
| BRPI0811280A2 (pt) | Compostos amino-heterocíclicos | |
| DK2185567T3 (da) | Substituerede bicyclolactam-forbindelser | |
| BRPI0811145A2 (pt) | Composto tetraidroisoquinolina 1-substituído | |
| BRPI1011791A2 (pt) | montagem para perfuração de fundo de poço | |
| BRPI1011683A2 (pt) | derivado isoquinolina substituída | |
| BRPI0807911A2 (pt) | Agonistas de alfa2c adrenorreceptor | |
| BRPI0810926A2 (pt) | Antagonista de crig | |
| BRPI0907780A2 (pt) | Sites transladados pelo usuário após fornecimento | |
| FI20075851A0 (fi) | Muodostusosa | |
| FR2933690B1 (fr) | Nanonitrure de bore cubique | |
| BRPI0922098A2 (pt) | composto inorgânicos | |
| DE602008000851D1 (de) | V-Motor | |
| DK3825306T3 (da) | Morphinanforbindelser | |
| BRPI0907519A2 (pt) | Antagonistas farmacoforos-pde4-muscarínicos duais | |
| BRPI0818337A2 (pt) | quimioterápico cristalino | |
| BRPI0820562A2 (pt) | Composição de formigamento trigeminal | |
| BRPI0820430A2 (pt) | Composto | |
| ES1065419Y (es) | Jamonero mejorado | |
| DK1982743T3 (da) | Slangeholder | |
| DE112007003605A5 (de) | Schutzbeschaltung |