ES2528947T3 - Mezcla de granulado, que comprende dos granulados distintos, para la distracción artificial del callo - Google Patents

Mezcla de granulado, que comprende dos granulados distintos, para la distracción artificial del callo Download PDF

Info

Publication number
ES2528947T3
ES2528947T3 ES10757729.8T ES10757729T ES2528947T3 ES 2528947 T3 ES2528947 T3 ES 2528947T3 ES 10757729 T ES10757729 T ES 10757729T ES 2528947 T3 ES2528947 T3 ES 2528947T3
Authority
ES
Spain
Prior art keywords
distraction
callus
artificial
granulate mixture
different granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10757729.8T
Other languages
English (en)
Inventor
Domonkos Horvath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CELGEN3D AG
Original Assignee
CELGEN3D AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CELGEN3D AG filed Critical CELGEN3D AG
Application granted granted Critical
Publication of ES2528947T3 publication Critical patent/ES2528947T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

Mezcla de granulado adecuada para la regeneración de un hueso, que contiene al menos una partícula expandible y al menos una partícula no deformable, en la que al menos una partícula expandible contiene un agente hinchante y donde el agente hinchante de al menos una partícula expandible está recubierto por un revestimiento biodegradable o por un envoltorio biodegradable.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8
imagen9
imagen10
imagen11
imagen12
imagen13
imagen14
imagen15
imagen16
imagen17

Claims (1)

  1. imagen1
ES10757729.8T 2009-09-14 2010-09-13 Mezcla de granulado, que comprende dos granulados distintos, para la distracción artificial del callo Active ES2528947T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009042493 2009-09-14
DE102009042493.8A DE102009042493B4 (de) 2009-09-14 2009-09-14 Granulatmischung, umfassend zwei verschiedene Granulate, zur künstlichen Kallusdistraktion
PCT/EP2010/005600 WO2011029622A2 (de) 2009-09-14 2010-09-13 Granulatmischung, umfassend zwei verschiedene granulate, zur künstlichen kallusdistraktion

Publications (1)

Publication Number Publication Date
ES2528947T3 true ES2528947T3 (es) 2015-02-13

Family

ID=43558257

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10757729.8T Active ES2528947T3 (es) 2009-09-14 2010-09-13 Mezcla de granulado, que comprende dos granulados distintos, para la distracción artificial del callo

Country Status (5)

Country Link
US (2) US8617612B2 (es)
EP (2) EP2810666A1 (es)
DE (1) DE102009042493B4 (es)
ES (1) ES2528947T3 (es)
WO (1) WO2011029622A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7771482B1 (en) 2000-05-09 2010-08-10 Ben-Zion Karmon Method for tissue expansion and regeneration using bioresorbable inflatable devices
IL243401A (en) 2015-12-29 2017-12-31 Zion Karmon Ben Instruments and methods for lifting Schneider membrane
IL248472A0 (en) 2016-10-13 2017-01-31 Zion Karmon Ben Devices for tissue growth

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706667A1 (de) * 1997-02-20 1998-08-27 Merck Patent Gmbh Knochenersatzmaterial mit einer Oberflächenbelegung mit Peptiden mit RGD-Aminosäuresequenz
AU2000246049A1 (en) 2000-05-29 2001-12-11 Domonkos Horvath Devices and medical membranes used for bone regeneration
JP2002325831A (ja) * 2001-05-02 2002-11-12 Asahi Optical Co Ltd 生体用充填材、および生体用充填材の製造方法
TW200400062A (en) * 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
DE10258773A1 (de) * 2002-12-16 2004-07-08 SDGI Holding, Inc., Wilmington Knochenersatzmaterial
DE102004036882A1 (de) 2004-07-22 2006-02-16 Ossacur Ag Bioresorbierbares Material zur Füllung von Knochendefekten
DE102005034420A1 (de) * 2004-12-23 2006-07-06 Ossacur Ag Gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten
DE102006042142A1 (de) * 2006-09-06 2008-03-27 Curasan Ag Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung
DE102006047248B4 (de) 2006-10-06 2012-05-31 Celgen Ag Dreidimensionale künstliche Kallusdistraktion
WO2008077257A1 (en) * 2006-12-22 2008-07-03 Mathys Ag Bettlach Precursor for the preparation of a pasty bone replacement material by admixture of a liquid
DE102007050440A1 (de) * 2007-10-18 2009-04-23 Alexakis, Antonis, Dr. med. dent. Beschichtetes Granulat zur Neubildung von Knochenmaterial
DE102008014560A1 (de) * 2008-03-15 2009-09-24 Celgen Ag Vorrichtung, umfassend ein Quellmittel und eine Ummantelung, zur künstlichen Kallusdistraktion

Also Published As

Publication number Publication date
EP2477667A2 (de) 2012-07-25
WO2011029622A2 (de) 2011-03-17
US20140105988A1 (en) 2014-04-17
US8617612B2 (en) 2013-12-31
DE102009042493A1 (de) 2011-04-21
US9144582B2 (en) 2015-09-29
EP2810666A1 (de) 2014-12-10
US20120171293A1 (en) 2012-07-05
DE102009042493B4 (de) 2016-07-21
WO2011029622A3 (de) 2011-07-07
EP2477667B1 (de) 2014-11-12

Similar Documents

Publication Publication Date Title
ES2568781T3 (es) Formulación de geles de polisacáridos
CL2007003108A1 (es) Compuestos derivados de n-hidroxiamida sustituida con heterociclos, inhibidores de histona desacetilasa; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad del grupo que consiste en enfermedad de huntington,
ES2649340T3 (es) Administración de fármacos activados por hipoxia y agentes antiangiogénicos para el tratamiento del cáncer
ES2557988T3 (es) Método para tratar enfermedades de próstata basado en el suministro local de principios activos
ES2604778T3 (es) Gránulos de oseltamivir fosfato y método de preparación de los mismos
ES2557303T3 (es) Agente terapéutico para la estenosis del canal espinal
ES2661582T3 (es) Efecto antiinflamatorio de la celulosa microfibrilada
ES2487496T3 (es) Agente para aliviar el síndrome metabólico
BRPI0721369A2 (pt) Péletes que compreendem uma matriz de substância ativa e um revestimento polimérico, e um método para produzir os referidos péletes
ES2596173T3 (es) Un proceso para la producción de HDPE bimodal con recuperación de cera
CL2012000891A1 (es) Material de soporte que comprende piel intacta de pescado descelularizada, donde el material de soporte comprende material de matriz extracelular a partir de la piel intacta de pescado y hasta aproximadamente 25% (p/p) de lípidos de la piel intacta de pescado; método para producir un material de soporte; uso del material.
CL2008002430A1 (es) Compuestos derivados de bencenosulfonamida, inhibidores de catepsina c; composicion farmaceutica que los comprende; y su uso para el tratamiento de la epoc.
CL2010001483A1 (es) Compuestos derivados de 5-fenil-1h-piridin-2-ona y 6-fenil-2h-piridazin-3-ona, inhibidores de tirosina-quinasa (btk); composicion farmaceutica que comprende a dichos compuestos y su uso para el tratamiento de un estado patologico inflamatorio y/o autoinmune.
CL2008000058A1 (es) Formulacion que comprende un anticuerpo anti-il13, un criprotector, y una solucion amortiguadora; composicion farmaceutica que la comprende; metodo para tratar un trastorno relacionado con il13; y formas farmaceuticas que la comprenden.
BRPI0814319A2 (pt) processo para preparar micropartículas que compreendem policaprolactona, micropartículas, gel injetável biodegradável, e, uso do gel
ES2528947T3 (es) Mezcla de granulado, que comprende dos granulados distintos, para la distracción artificial del callo
ES2563777T3 (es) Compuestos de nitrona para tratar la pérdida auditiva sensorineural
AR059330A1 (es) Composiciones acondicionadoras del cabello
CL2008001273A1 (es) Compuestos derivados de heterociclos, inhibidores de proteina activadora de la 5-lipoxigenasa (flap); composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la inflamacion, enfermedad cardiovascular, asma
CL2009000914A1 (es) Compuestos derivados de 1-ciano-3-pirrolidinil-n-sustituidas-sulfonamidas, inhibidores de catepsina c; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de una enfermedad pulmonar obstructiva cronica.
BRPI0709769B8 (pt) implantes biodegradáveis para o tratamento de estados associados à dopamina
ES2484721T3 (es) Mezcla fluidizante para composición hidráulica
CL2007003356A1 (es) Compuestos derivados de benzopirazoles; proceso para la preparacion de dichos compuestos; composicion farmaceutica que comprende a dichos compuestos y otro agente activo; y su uso para el tratamiento del asma, inflamacion, entre otras enfermedades.
RS54329B1 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING RIFAXIMINE, PROCEDURES FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF VAGINAL INFECTIONS
BRPI0912539A2 (pt) composto, composição farmacêutica , método para tratar uma doença, e, uso do composto.