ES2507518T3 - Autoinyector - Google Patents

Autoinyector Download PDF

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Publication number
ES2507518T3
ES2507518T3 ES09710510.0T ES09710510T ES2507518T3 ES 2507518 T3 ES2507518 T3 ES 2507518T3 ES 09710510 T ES09710510 T ES 09710510T ES 2507518 T3 ES2507518 T3 ES 2507518T3
Authority
ES
Spain
Prior art keywords
piston rod
hollow piston
drive nut
dose
dose setting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09710510.0T
Other languages
English (en)
Inventor
Istvan Bartha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHL Group AB
Original Assignee
SHL Group AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHL Group AB filed Critical SHL Group AB
Application granted granted Critical
Publication of ES2507518T3 publication Critical patent/ES2507518T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

Dispositivo de autoinyección que tiene un extremo delantero y un extremo trasero dispuesto para comprender: - un alojamiento trasero y un alojamiento (10) de recipiente, conectados de manera liberable entre sí; - un recipiente (12) de medicamento dispuesto dentro del alojamiento de recipiente, en el que el recipiente tiene una abertura delantera con o para un elemento de administración para administrar el medicamento a través de la misma y al menos un tapón móvil; - un mecanismo de fijación de dosis que puede fijar y volver a fijar una dosis de medicamento; - una tuerca (18) de accionamiento conectada de manera liberable con el mecanismo de fijación de dosis; caracterizado porque dicho dispositivo comprende además: - un vástago (14) de émbolo hueco conectado de manera rotatoria con dicha tuerca de accionamiento y dispuesto para tener su extremo delantero en contacto con dicho tapón; - un elemento (46) de acumulación de energía que tiene un primer extremo conectado con el mecanismo de fijación de dosis y un segundo extremo conectado con un punto fijo del alojamiento trasero, de tal manera que cuando se actúa sobre dicho mecanismo de fijación de dosis para fijar una dosis, dicho elemento de acumulación de energía acumula energía como al menos una etapa predeterminada; - un mecanismo (24) de activación conectado de manera liberable con dicha tuerca de accionamiento y que puede bloquear dicha tuerca de accionamiento frente a la rotación cuando está fijándose una dosis y liberar dicha tuerca de accionamiento cuando se activa manualmente dicho mecanismo de activación de tal manera que dicho vástago de émbolo hueco se desplaza linealmente hacia el extremo delantero del dispositivo mediante la rotación de dicha tuerca de accionamiento debido a la energía acumulada en el elemento de acumulación de energía y transferida a través del mecanismo de fijación de dosis; - un mecanismo de colocación conectado operativamente con dicho vástago de émbolo hueco y que puede bloquear dicho vástago de émbolo hueco frente a un desplazamiento elástico y axial mediante rotación; en el que dicho mecanismo de colocación comprende una primera tuerca (28) de bloqueo rotacionalmente bloqueada pero axialmente deslizable que rodea a dicho vástago de émbolo hueco y dispuesta para actuar conjuntamente con medios (38) de bloqueo flexibles dispuestos en dicho alojamiento trasero para bloquear dicha primera tuerca de bloqueo frente a la rotación; y un elemento (52) elástico dispuesto dentro de dicho vástago de émbolo hueco que puede permitir que dicho vástago de émbolo hueco se desplace de manera elástica y axial cuando se desbloquea dicha primera tuerca de bloqueo.

Description

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Claims (1)

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    imagen2
ES09710510.0T 2008-02-12 2009-02-03 Autoinyector Active ES2507518T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0800313 2008-02-12
SE0800313 2008-02-12
PCT/EP2009/051202 WO2009101005A1 (en) 2008-02-12 2009-02-03 Auto-injector

Publications (1)

Publication Number Publication Date
ES2507518T3 true ES2507518T3 (es) 2014-10-15

Family

ID=40673304

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09710510.0T Active ES2507518T3 (es) 2008-02-12 2009-02-03 Autoinyector

Country Status (9)

Country Link
US (1) US8632507B2 (es)
EP (1) EP2254624B1 (es)
JP (1) JP4977252B2 (es)
CN (1) CN101951979B (es)
AU (1) AU2009214255B2 (es)
DK (1) DK2254624T3 (es)
ES (1) ES2507518T3 (es)
PL (1) PL2254624T3 (es)
WO (1) WO2009101005A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60323729D1 (de) 2002-02-11 2008-11-06 Antares Pharma Inc Intradermales injektionsgerät
JP5216328B2 (ja) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド あらかじめ充填された針補助シリンジジェット式注射器
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
WO2007131025A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injector with adjustable dosing
WO2009114542A1 (en) 2008-03-10 2009-09-17 Antares Pharma, Inc. Injector safety device
AU2009279719B2 (en) 2008-08-05 2015-07-23 Antares Pharma, Inc. Multiple dosage injector
US9358341B2 (en) 2009-09-30 2016-06-07 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
AR079004A1 (es) 2009-09-30 2011-12-21 Sanofi Aventis Deutschland Dispositivo de dispensacion de farmacos
DK2493529T3 (en) * 2009-10-26 2016-05-17 Shl Group Ab Drug delivery device
US10322244B2 (en) 2009-12-15 2019-06-18 Shl Group Ab Medicament delivery device
DK2512561T3 (en) 2009-12-15 2016-05-09 Shl Group Ab DRUG DELIVERY DEVICES
US10322243B2 (en) 2009-12-15 2019-06-18 Shl Group Ab Medicament delivery device
TW201138882A (en) 2010-01-25 2011-11-16 Sanofi Aventis Deutschland Drive assembly for a drug delivery device and drug delivery device
DK2536452T3 (da) 2010-02-18 2019-01-02 Sanofi Aventis Deutschland Autoinjektor
EP2399635A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468330A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
USRE48593E1 (en) 2010-12-21 2021-06-15 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2468333A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2688616B1 (en) * 2011-03-24 2018-02-14 SHL Group AB Medicament delivery device
AR086256A1 (es) * 2011-05-06 2013-11-27 Sanofi Aventis Deutschland Conjunto de impulso para un dispositivo de administracion de farmacos y correspondiente dispositivo de administracion de farmacos
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
CN104066467B (zh) * 2011-12-06 2016-10-26 Shl集团有限责任公司 药物输送装置
PL220720B1 (pl) * 2012-02-08 2015-12-31 Copernicus Spółka Z Ograniczoną Odpowiedzialnością Urządzenie wstrzykujące z mechanizmem resetu dawki
DK2822618T3 (da) 2012-03-06 2024-01-22 Antares Pharma Inc Forfyldt nål med brudkraftfunktion
EP2833944A4 (en) 2012-04-06 2016-05-25 Antares Pharma Inc ADMINISTRATION OF TESTOSTERONE COMPOSITIONS BY NEEDLE-SUPPORTED NOZZLE INJECTION
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9616174B2 (en) * 2012-05-25 2017-04-11 Aptar France Sas Autoinjector
CN104736188B (zh) * 2012-10-15 2017-09-01 诺和诺德股份有限公司 弹簧驱动的注射装置
EP2722065A1 (en) * 2012-10-18 2014-04-23 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2953667B1 (en) 2013-02-11 2019-10-23 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
EP2823841A1 (en) 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
EP2923714A1 (en) 2014-03-28 2015-09-30 Sanofi-Aventis Deutschland GmbH Autoinjector triggered by skin contact
US10661014B2 (en) 2015-01-21 2020-05-26 Antares Pharma, Inc. Injection device having variable dosing
US10898646B2 (en) 2016-04-29 2021-01-26 Shl Medical Ag Container holder assembly
EP3323448A1 (en) 2016-11-18 2018-05-23 Carebay Europe Ltd. Medicament delivery device
FR3072297B1 (fr) * 2017-10-17 2023-05-12 Edix Sa Dispositif d'injection manuelle
IT201800020467A1 (it) * 2018-12-20 2020-06-20 Medirio Sa Dispositivo e sistema di somministrazione di un fluido medicale e relativo metodo di somministrazione
JP2022534248A (ja) * 2019-05-30 2022-07-28 ベクトン・ディキンソン・アンド・カンパニー 薬物送達デバイス用のカートリッジアダプタ

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ATE318157T1 (de) * 1999-08-05 2006-03-15 Becton Dickinson Co Stiftförmige medikamentenabgabevorrichtung
SE518981C2 (sv) * 2000-12-14 2002-12-17 Shl Medical Ab Autoinjektor
DE10163326A1 (de) * 2001-07-30 2003-02-27 Disetronic Licensing Ag Verabreichungsgerät mit Dosiervorrichtung
US20050101919A1 (en) * 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
US20090005735A1 (en) * 2006-03-03 2009-01-01 Shl Group Ab Medical Device with Orientation Sensitive Priming Mechanism

Also Published As

Publication number Publication date
JP2011511659A (ja) 2011-04-14
US20110034881A1 (en) 2011-02-10
EP2254624A1 (en) 2010-12-01
WO2009101005A1 (en) 2009-08-20
DK2254624T3 (da) 2014-10-06
CN101951979B (zh) 2013-03-20
CN101951979A (zh) 2011-01-19
AU2009214255B2 (en) 2011-09-29
AU2009214255A1 (en) 2009-08-20
PL2254624T3 (pl) 2015-01-30
EP2254624B1 (en) 2014-07-02
US8632507B2 (en) 2014-01-21
JP4977252B2 (ja) 2012-07-18

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