ES2498274T3 - Polimorfismos genéticos en degeneración macular relacionada con la edad - Google Patents
Polimorfismos genéticos en degeneración macular relacionada con la edad Download PDFInfo
- Publication number
- ES2498274T3 ES2498274T3 ES12185155.4T ES12185155T ES2498274T3 ES 2498274 T3 ES2498274 T3 ES 2498274T3 ES 12185155 T ES12185155 T ES 12185155T ES 2498274 T3 ES2498274 T3 ES 2498274T3
- Authority
- ES
- Spain
- Prior art keywords
- patient
- seq
- dme
- dna
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/113—PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/137—Ligase Chain Reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11166708P | 2008-11-05 | 2008-11-05 | |
| US111667P | 2008-11-05 | ||
| US17485609P | 2009-05-01 | 2009-05-01 | |
| US174856P | 2009-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2498274T3 true ES2498274T3 (es) | 2014-09-24 |
Family
ID=41650496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12185155.4T Active ES2498274T3 (es) | 2008-11-05 | 2009-11-05 | Polimorfismos genéticos en degeneración macular relacionada con la edad |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20120003641A1 (https=) |
| EP (2) | EP2356250A2 (https=) |
| JP (1) | JP5701216B2 (https=) |
| KR (1) | KR101719376B1 (https=) |
| CN (2) | CN103333952B (https=) |
| AU (1) | AU2009313475B2 (https=) |
| CA (1) | CA2740242A1 (https=) |
| DK (1) | DK2540843T3 (https=) |
| ES (1) | ES2498274T3 (https=) |
| IL (1) | IL211995A (https=) |
| MX (1) | MX2011004763A (https=) |
| PL (1) | PL2540843T3 (https=) |
| SI (1) | SI2540843T1 (https=) |
| WO (1) | WO2010054110A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| CA2726691C (en) | 2008-07-25 | 2016-11-08 | Infocom Corporation | Use of oncogene nrf2 for cancer prognosis |
| EP2678441B1 (en) * | 2011-02-23 | 2017-10-18 | Sanofi | Single nucleotide polymorphisms in the promoter of vegfa gene and their use as predictive markers for anti-vegf treatments |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| JP6040227B2 (ja) | 2011-05-19 | 2016-12-07 | アジーナ バイオサイエンス， インコーポレイテッド | マルチプレックス核酸同定のための製品およびプロセス |
| BR112014003811A2 (pt) * | 2011-08-26 | 2017-03-14 | Hoffmann La Roche | método para predizer benefício clínico no tratamento de transtornos de neurodesenvolvimento, neurológicos ou neuropsiquiátricos |
| CN103917556B (zh) * | 2011-10-14 | 2018-02-06 | 霍夫曼-拉罗奇有限公司 | 抗HtrA1抗体及使用方法 |
| US20140004105A1 (en) * | 2012-06-29 | 2014-01-02 | Sequenom, Inc. | Age-related macular degeneration diagnostics |
| AU2014306867B2 (en) | 2013-08-12 | 2017-10-26 | Genentech, Inc. | Compositions and method for treating complement-associated conditions |
| EP3137503A1 (en) | 2014-05-01 | 2017-03-08 | Genentech, Inc. | Anti-factor d antibody variants and uses thereof |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR102486321B1 (ko) | 2014-07-18 | 2023-01-09 | 사노피 | 암을 앓고 있는 것으로 의심되는 환자를 아플리베르셉트로 치료한 결과를 예측하는 방법 |
| WO2016100745A2 (en) * | 2014-12-19 | 2016-06-23 | Children's Hospital Medical Center | Methods and compositions related to transplant-associated thrombotic microangiopathy |
| WO2016172571A1 (en) | 2015-04-24 | 2016-10-27 | Agena Bioscience, Inc. | Multiplexed method for the identification and quantitation of minor alleles and polymorphisms |
| CN104894261B (zh) * | 2015-06-02 | 2020-02-14 | 北京医院 | 一种预测雷珠单抗治疗年龄相关性黄斑变性疗效的试剂盒 |
| CN104878105B (zh) * | 2015-06-02 | 2017-10-31 | 北京医院 | 一种预测雷珠单抗治疗年龄相关性黄斑变性疗效的试剂 |
| US10407510B2 (en) | 2015-10-30 | 2019-09-10 | Genentech, Inc. | Anti-factor D antibodies and conjugates |
| WO2017075252A1 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibody variant conjugates and uses thereof |
| KR102799807B1 (ko) | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| CN109073660B (zh) * | 2016-02-29 | 2022-10-28 | 麦恩泰科特有限公司 | 可用于治疗湿性年龄相关性黄斑变性的预测性标志物 |
| HUE064412T2 (hu) | 2016-06-21 | 2024-03-28 | Orion Ophthalmology LLC | Heterociklusos prolinamid-származékok |
| JP7164521B2 (ja) | 2016-06-21 | 2022-11-01 | オリオン・オフサルモロジー・エルエルシー | 炭素環式プロリンアミド誘導体 |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN113373236B (zh) * | 2021-02-19 | 2021-12-31 | 中国科学院北京基因组研究所(国家生物信息中心) | 一种获得中国人群个体年龄的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8311018D0 (en) | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4998617A (en) | 1986-09-15 | 1991-03-12 | Laura Lupton Inc | Facial cosmetic liquid make up kit |
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5256775A (en) | 1989-06-05 | 1993-10-26 | Gilead Sciences, Inc. | Exonuclease-resistant oligonucleotides |
| FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
| US5264564A (en) | 1989-10-24 | 1993-11-23 | Gilead Sciences | Oligonucleotide analogs with novel linkages |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5952172A (en) | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5968740A (en) | 1995-07-24 | 1999-10-19 | Affymetrix, Inc. | Method of Identifying a Base in a Nucleic Acid |
| JP3957765B2 (ja) | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗ｖｅｇｆ抗体 |
| WO1999013108A1 (en) | 1997-09-10 | 1999-03-18 | University Of Maryland, Baltimore | Method of amplifying dna and rna mismatch cleavage products |
| CN102618644A (zh) * | 2004-11-18 | 2012-08-01 | 耶鲁大学 | 治疗眼病的方法和组合物 |
| US7972787B2 (en) * | 2007-02-16 | 2011-07-05 | Massachusetts Eye And Ear Infirmary | Methods for detecting age-related macular degeneration |
-
2009
- 2009-11-05 CN CN201310181349.5A patent/CN103333952B/zh not_active Expired - Fee Related
- 2009-11-05 US US13/127,433 patent/US20120003641A1/en not_active Abandoned
- 2009-11-05 AU AU2009313475A patent/AU2009313475B2/en not_active Ceased
- 2009-11-05 SI SI200931009T patent/SI2540843T1/sl unknown
- 2009-11-05 EP EP09748682A patent/EP2356250A2/en not_active Withdrawn
- 2009-11-05 JP JP2011534924A patent/JP5701216B2/ja not_active Expired - Fee Related
- 2009-11-05 CA CA2740242A patent/CA2740242A1/en not_active Abandoned
- 2009-11-05 KR KR1020117010284A patent/KR101719376B1/ko not_active Expired - Fee Related
- 2009-11-05 PL PL12185155T patent/PL2540843T3/pl unknown
- 2009-11-05 EP EP12185155.4A patent/EP2540843B1/en active Active
- 2009-11-05 ES ES12185155.4T patent/ES2498274T3/es active Active
- 2009-11-05 MX MX2011004763A patent/MX2011004763A/es active IP Right Grant
- 2009-11-05 CN CN200980144066.5A patent/CN102203296B/zh not_active Expired - Fee Related
- 2009-11-05 WO PCT/US2009/063434 patent/WO2010054110A2/en not_active Ceased
- 2009-11-05 DK DK12185155.4T patent/DK2540843T3/da active
-
2011
- 2011-03-29 IL IL211995A patent/IL211995A/en active IP Right Grant
-
2016
- 2016-07-20 US US15/215,426 patent/US20170159114A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2356250A2 (en) | 2011-08-17 |
| EP2540843A3 (en) | 2013-05-29 |
| DK2540843T3 (da) | 2014-09-01 |
| IL211995A0 (en) | 2011-06-30 |
| KR101719376B1 (ko) | 2017-03-23 |
| MX2011004763A (es) | 2011-06-01 |
| JP2012507988A (ja) | 2012-04-05 |
| WO2010054110A3 (en) | 2010-08-19 |
| AU2009313475A1 (en) | 2010-05-14 |
| PL2540843T3 (pl) | 2014-12-31 |
| AU2009313475B2 (en) | 2016-06-02 |
| EP2540843A2 (en) | 2013-01-02 |
| SI2540843T1 (sl) | 2014-10-30 |
| KR20110081836A (ko) | 2011-07-14 |
| US20120003641A1 (en) | 2012-01-05 |
| HK1173751A1 (en) | 2013-05-24 |
| IL211995A (en) | 2014-04-30 |
| US20170159114A1 (en) | 2017-06-08 |
| JP5701216B2 (ja) | 2015-04-15 |
| CN103333952A (zh) | 2013-10-02 |
| WO2010054110A2 (en) | 2010-05-14 |
| CN102203296A (zh) | 2011-09-28 |
| CA2740242A1 (en) | 2010-05-14 |
| CN103333952B (zh) | 2015-07-29 |
| BRPI0914368A2 (pt) | 2015-10-20 |
| EP2540843B1 (en) | 2014-07-02 |
| CN102203296B (zh) | 2014-12-03 |
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