ES2434039T3 - Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación - Google Patents

Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación Download PDF

Info

Publication number
ES2434039T3
ES2434039T3 ES07766836T ES07766836T ES2434039T3 ES 2434039 T3 ES2434039 T3 ES 2434039T3 ES 07766836 T ES07766836 T ES 07766836T ES 07766836 T ES07766836 T ES 07766836T ES 2434039 T3 ES2434039 T3 ES 2434039T3
Authority
ES
Spain
Prior art keywords
ccl2
lymphocytes
diseases
autoimmune
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07766836T
Other languages
English (en)
Spanish (es)
Inventor
Liat Flaishon
Idit Shachar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of ES2434039T3 publication Critical patent/ES2434039T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES07766836T 2006-07-24 2007-06-28 Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación Active ES2434039T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83260006P 2006-07-24 2006-07-24
US832600P 2006-07-24
PCT/IL2007/000806 WO2008012796A2 (en) 2006-07-24 2007-06-28 Pharmaceutical compositions comprising ccl2 and use of same for the treatment of inflammation

Publications (1)

Publication Number Publication Date
ES2434039T3 true ES2434039T3 (es) 2013-12-13

Family

ID=38981868

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07766836T Active ES2434039T3 (es) 2006-07-24 2007-06-28 Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación

Country Status (7)

Country Link
US (2) US7919077B2 (https=)
EP (1) EP2056857B1 (https=)
JP (1) JP2009544690A (https=)
AU (1) AU2007278054B2 (https=)
CA (1) CA2658719A1 (https=)
ES (1) ES2434039T3 (https=)
WO (1) WO2008012796A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007278054B2 (en) * 2006-07-24 2012-11-22 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising CCL2 and use of same for the treatment of inflammation
US20120070449A1 (en) 2009-05-28 2012-03-22 Yeda Research And Development Co. Ltd. Methods of treating inflammation
CN101829075B (zh) * 2010-04-27 2011-07-20 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
WO2012131680A2 (en) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions and methods for treating inflammation
US20160000936A1 (en) 2014-06-10 2016-01-07 Abbvie Inc. Biomarkers for inflammatory disease and methods of using same
EP3288587A4 (en) * 2015-04-29 2018-09-12 Sanford-Burnham Medical Research Institute Modulation of immune response using btla agonist antibodies
CN108697804B (zh) * 2015-10-05 2022-11-15 德克萨斯州立大学董事会 用于软骨损伤的检测和治疗的微米和纳米装置
KR102066149B1 (ko) * 2018-08-17 2020-01-14 고려대학교 산학협력단 Ccl2를 유효성분으로 포함하는 임신촉진용 조성물
KR102154235B1 (ko) * 2019-02-11 2020-09-09 고려대학교 산학협력단 Ccl2를 유효성분으로 포함하는 산유량 증가용 조성물, 및 유방염 예방 또는 치료용 약학적 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05271093A (ja) * 1992-03-30 1993-10-19 Toray Ind Inc 血管内皮細胞増殖剤
JP2000516611A (ja) * 1996-08-14 2000-12-12 ワーナー―ランバート・コンパニー Mcp―1アンタゴニストとしての2―フェニルベンズイミダゾール誘導体
US6316420B1 (en) * 1998-07-28 2001-11-13 Technion Research And Development Foundation Ltd. DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis
GB0016138D0 (en) * 2000-06-30 2000-08-23 Novartis Ag Organic compounds
ATE323772T1 (de) * 2000-07-06 2006-05-15 Deutsches Krebsforsch Regulatorische sequenzen des humanen mcp-1 gens
US7601692B2 (en) * 2000-11-28 2009-10-13 Compugen Ltd. MCP-1 splice variants and methods of using same
TWI245761B (en) * 2001-03-01 2005-12-21 Telik Inc Antagonists of MCP-1 function and methods of use thereof
CA2496419A1 (en) * 2002-08-19 2004-02-26 Abgenix, Inc. Antibodies directed to monocyte chemo-attractant protein-1 (mcp-1) and uses thereof
JP4601936B2 (ja) * 2002-10-29 2010-12-22 株式会社ミノファーゲン製薬 Mcp−1産生抑制のための薬学的組成物
AR046594A1 (es) * 2003-10-16 2005-12-14 Applied Research Systems Usos terapeuticos de variantes de quemoquina
CA2544924A1 (en) * 2003-11-05 2005-05-19 Centocor, Inc. Methods and compositions for treating mcp-1 related pathologies
MX2008002101A (es) * 2005-08-12 2008-04-19 Schering Corp Fusiones de la proteina-1 quimiotactica de monocito.
CA2646931C (en) * 2006-03-16 2016-05-24 Protagonists Ltd. Combination of cytokine and cytokine receptor for altering immune system functioning
AU2007278054B2 (en) * 2006-07-24 2012-11-22 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising CCL2 and use of same for the treatment of inflammation

Also Published As

Publication number Publication date
JP2009544690A (ja) 2009-12-17
AU2007278054A1 (en) 2008-01-31
WO2008012796A2 (en) 2008-01-31
CA2658719A1 (en) 2008-01-31
EP2056857A4 (en) 2011-02-16
AU2007278054B2 (en) 2012-11-22
US7919077B2 (en) 2011-04-05
EP2056857B1 (en) 2013-08-21
EP2056857A2 (en) 2009-05-13
US20090239799A1 (en) 2009-09-24
US20110165116A1 (en) 2011-07-07
WO2008012796A3 (en) 2009-04-09

Similar Documents

Publication Publication Date Title
ES2434039T3 (es) Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación
Schinocca et al. Role of the IL-23/IL-17 pathway in rheumatic diseases: an overview
US7354575B2 (en) Method and pharmaceutical composition for treating inflammation
Klück et al. The role of interleukin-1 family members in hyperuricemia and gout
Gerdes et al. Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis
US8454967B2 (en) Compositions and methods for modulating the immune system
Shi et al. Cinnamtannin D1 attenuates autoimmune arthritis by regulating the balance of Th17 and treg cells through inhibition of aryl hydrocarbon receptor expression
Berghmans et al. Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes
Huang et al. Inhibitory effects of endogenous and exogenous interferon‐γ on bronchial hyperresponsiveness, allergic inflammation and T‐helper 2 cytokines in Brown–Norway rats
Becker The spreading of HIV-1 infection in the human organism is caused by fractalkine trafficking of the infected lymphocytes—a review, hypothesis and implications for treatment
EP2164507B1 (en) Treatment of allergic disease with immunomodulator compounds
US20230404979A1 (en) Alpha-2 adrenergic receptor agonists to reduce mortality and improve outcomes in viral respiratory syndromes
US12239650B2 (en) Compounds for treating and preventing net associated complications
Zhou et al. Trichosanthin-derived peptide Tk-PQ attenuates immune rejection in mouse tracheal allotransplant model by suppressing PI3K-Akt and inducing type II immune polarization
P Sarapultsev et al. Effect of a new class of compounds of the group of substituted 5R1, 6H2-1, 3, 4-thiadiazine-2-amines on the inflammatory and cytokine response in experimental myocardial infarction
JP2020511418A (ja) Ilc2細胞に関連する疾患を処置する方法
ODonnell et al. PS-B06-8: EXPLORING THE ROLE OF NECROPTOSIS IN HYPERTENSION
Omert et al. A role of neutrophils in the down-regulation of IL-6 and CD14 following hemorrhagic shock
CN114470196B (zh) CCL3/CCR4中和抗体、NF-κB抑制剂在制备NEC治疗药物中的用途
RU2457789C2 (ru) Способ иммунотерапии гнойного риносинусита
Kono et al. Nafamostat mesylate therapy for systemic lupus erythematosus with nephrotic syndrome: a case report
CN119701016A (zh) 促进march2基因表达的试剂在制备治疗主动脉瘤/夹层药物中的应用
Kiani et al. Case Report Severe Pulmonary Hypertension as Initial Presentation of SLE: A Case Report and Literature Review
JP2006298775A (ja) 選択的Th2免疫反応抑制剤
WO1999011282A1 (en) Compositions and methods for contraception in or sterilization of mammals