ES2425179T3 - Métodos para el tratamiento de trastornos relacionados con beta-amiloide y composiciones para los mismos - Google Patents

Métodos para el tratamiento de trastornos relacionados con beta-amiloide y composiciones para los mismos Download PDF

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Publication number
ES2425179T3
ES2425179T3 ES07870808T ES07870808T ES2425179T3 ES 2425179 T3 ES2425179 T3 ES 2425179T3 ES 07870808 T ES07870808 T ES 07870808T ES 07870808 T ES07870808 T ES 07870808T ES 2425179 T3 ES2425179 T3 ES 2425179T3
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ES
Spain
Prior art keywords
modulator
disease
methods
peptide
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07870808T
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English (en)
Spanish (es)
Inventor
Marc Flajolet
Paul Greengard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
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Rockefeller University
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Application filed by Rockefeller University filed Critical Rockefeller University
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Publication of ES2425179T3 publication Critical patent/ES2425179T3/es
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES07870808T 2006-10-25 2007-10-24 Métodos para el tratamiento de trastornos relacionados con beta-amiloide y composiciones para los mismos Active ES2425179T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85433306P 2006-10-25 2006-10-25
US854333P 2006-10-25
PCT/US2007/022519 WO2008066626A2 (en) 2006-10-25 2007-10-24 METHODS FOR THE TREATMENT OF Aβ RELATED DISORDERS AND COMPOSITIONS THEREFOR

Publications (1)

Publication Number Publication Date
ES2425179T3 true ES2425179T3 (es) 2013-10-11

Family

ID=39468422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07870808T Active ES2425179T3 (es) 2006-10-25 2007-10-24 Métodos para el tratamiento de trastornos relacionados con beta-amiloide y composiciones para los mismos

Country Status (5)

Country Link
US (1) US9532980B2 (enExample)
EP (1) EP2077838B1 (enExample)
JP (3) JP5518479B2 (enExample)
ES (1) ES2425179T3 (enExample)
WO (1) WO2008066626A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009146301A1 (en) 2008-05-27 2009-12-03 Yale University TARGETING TGF-β AS A THERAPY FOR ALZHEIMER'S DISEASE
EP2307440A4 (en) * 2008-07-01 2012-12-19 Zacharon Pharmaceuticals Inc HEPARAN SULFATE INHIBITORS
WO2010065917A1 (en) 2008-12-05 2010-06-10 The Regents Of The University Of California Methods of treating neurological disorders
US9414409B2 (en) 2012-02-06 2016-08-09 Samsung Electronics Co., Ltd. Method and apparatus for transmitting/receiving data on multiple carriers in mobile communication system
JPWO2014007367A1 (ja) * 2012-07-05 2016-06-02 国立大学法人 東京大学 同一試料中の2種の物質を検出又は測定する方法
ES2728932T3 (es) 2014-01-09 2019-10-29 Intra Cellular Therapies Inc Compuestos orgánicos
WO2018133835A1 (en) * 2017-01-20 2018-07-26 National Institute Of Biological Sciences, Beijing Nucleoside analogue regulating mammalian circadian rhythm
JP7506473B2 (ja) * 2019-12-20 2024-06-26 ポッカサッポロフード&ビバレッジ株式会社 アミロイドβ蓄積抑制剤
CN113234664B (zh) * 2021-05-11 2024-05-10 澳门大学 一种胰腺祖细胞的制备方法及其应用

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US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5633425A (en) * 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) * 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5770429A (en) * 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ES2246502T3 (es) * 1990-08-29 2006-02-16 Genpharm International, Inc. Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
US5789650A (en) * 1990-08-29 1998-08-04 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US6060296A (en) * 1991-07-03 2000-05-09 The Salk Institute For Biological Studies Protein kinases
US5157378A (en) * 1991-08-06 1992-10-20 North-South Corporation Integrated firefighter safety monitoring and alarm system
US5932448A (en) * 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US5545580A (en) * 1995-09-19 1996-08-13 United Microelectronics Corporation Multi-state read-only memory using multiple polysilicon selective depositions
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6288089B1 (en) * 1998-12-21 2001-09-11 Michael Zawada Use of kinase inhibitors for treating neurodegenerative diseases
AU4798000A (en) 1999-04-09 2000-11-14 Smithkline Beecham Corporation Triarylimidazoles
KR100722176B1 (ko) * 1999-06-08 2007-05-29 아벤티스 파마슈티칼스 인크. 일주기 리듬 단백질을 변화시키기 위한 스크리닝 방법
DE69912808T2 (de) * 1999-12-08 2004-09-30 Centre National De La Recherche Scientifique (C.N.R.S.) Verwendung von Hymenialdisin und dessen Derivaten zur Herstellung therapeutischer Mittel
US6448057B1 (en) * 2001-03-22 2002-09-10 Applera Corporation Isolated human casein kinase proteins, nucleic acid molecules encoding human casein kinase proteins, and uses thereof
JP2004536597A (ja) * 2001-06-18 2004-12-09 ザ ロックフェラー ユニバーシティー 代謝共役型グルタミン酸受容体シグナル伝達経路を介する神経機能の調節
AU2002324666B2 (en) 2001-08-10 2007-10-11 The Rockefeller University Compostions and methods for modulation of DARPP-32 phosphorylation
US7008666B2 (en) * 2001-11-26 2006-03-07 Hormos Nutraceutical Oy Ltd. Method of inhibiting overactivity of phagocytes or lymphocytes in an individual
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WO2005105987A1 (en) * 2004-04-28 2005-11-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with casein kinase 1, delta, isoform 2 (csnk1d iso 2)

Also Published As

Publication number Publication date
JP2014193865A (ja) 2014-10-09
WO2008066626A3 (en) 2008-12-11
JP5518479B2 (ja) 2014-06-11
US9532980B2 (en) 2017-01-03
JP2017014197A (ja) 2017-01-19
EP2077838A4 (en) 2010-10-27
EP2077838B1 (en) 2013-04-03
EP2077838A2 (en) 2009-07-15
US20100143361A1 (en) 2010-06-10
WO2008066626A2 (en) 2008-06-05
JP2010507666A (ja) 2010-03-11

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