ES2417009T3 - Derivados de benzomorfolina y métodos de uso - Google Patents

Derivados de benzomorfolina y métodos de uso Download PDF

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Publication number
ES2417009T3
ES2417009T3 ES08845711T ES08845711T ES2417009T3 ES 2417009 T3 ES2417009 T3 ES 2417009T3 ES 08845711 T ES08845711 T ES 08845711T ES 08845711 T ES08845711 T ES 08845711T ES 2417009 T3 ES2417009 T3 ES 2417009T3
Authority
ES
Spain
Prior art keywords
compound
usa
formula
vegf
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08845711T
Other languages
English (en)
Spanish (es)
Inventor
Jean-Christophe Harmange
Matthew W. Martin
Yohannes Teffera
Raju Subramanian
Ryan White
Roger Zanon
Jay Larrow
Joseph F. Payack
Mina Dilmeghani Seran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ES2417009T3 publication Critical patent/ES2417009T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES08845711T 2007-10-29 2008-10-28 Derivados de benzomorfolina y métodos de uso Active ES2417009T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94807P 2007-10-29 2007-10-29
US948P 2007-10-29
PCT/US2008/012224 WO2009058267A2 (en) 2007-10-29 2008-10-28 Benzomorpholine derivatives and methods of use

Publications (1)

Publication Number Publication Date
ES2417009T3 true ES2417009T3 (es) 2013-08-05

Family

ID=40394086

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08845711T Active ES2417009T3 (es) 2007-10-29 2008-10-28 Derivados de benzomorfolina y métodos de uso

Country Status (8)

Country Link
US (1) US7795254B2 (https=)
EP (1) EP2220078B1 (https=)
JP (1) JP5343082B2 (https=)
AU (1) AU2008319366B2 (https=)
CA (1) CA2703257C (https=)
ES (1) ES2417009T3 (https=)
MX (1) MX2010004620A (https=)
WO (1) WO2009058267A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH684182A5 (de) 1991-10-15 1994-07-29 Escher Wyss Ag Rotationsdruckmaschine.
RU2585683C2 (ru) 2010-05-19 2016-06-10 Сандоз Аг Очистка позаконазола и промежуточных продуктов для синтеза позаконазола
CN102892762B (zh) * 2010-05-19 2016-04-20 桑多斯股份公司 制备泊沙康唑中间体
EP2571847B1 (en) 2010-05-19 2016-09-21 Sandoz AG Process for the preparation of chiral hydrazides
CN103635465A (zh) 2011-06-16 2014-03-12 桑多斯股份公司 制备手性化合物的方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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US3755332A (en) 1971-07-01 1973-08-28 Ciba Geigy Corp Substituted 4 indazolaminoquinolines
US4916135A (en) 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB9323290D0 (en) 1992-12-10 1994-01-05 Zeneca Ltd Quinazoline derivatives
AU4547396A (en) 1995-01-31 1996-08-21 Zenyaku Kogyo Kabushiki Kaisha Thioquinoline derivatives
GB9505702D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd Fungicidal compounds
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
EP0860433B1 (en) 1995-11-07 2002-07-03 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
BR9607089A (pt) 1995-11-14 1997-11-11 Pharmacia & Upjohn Spa Compostos de pirimidina condensada biciclica composição farmacéutica utilização e produtos que contém os mesmos e processo para a preparação desses compostos
GB9603095D0 (en) 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
DE19614718A1 (de) 1996-04-15 1997-10-16 Hoechst Schering Agrevo Gmbh Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung, und ihre Verwendung als Schädlingsbekämpfungsmittel
GB9800575D0 (en) 1998-01-12 1998-03-11 Glaxo Group Ltd Heterocyclic compounds
EP1073640B1 (en) 1998-04-23 2005-04-13 Takeda Pharmaceutical Company Limited Naphthalene derivatives, their production and use
KR20010089171A (ko) 1998-08-21 2001-09-29 추후제출 퀴나졸린 유도체
PT1154774E (pt) 1999-02-10 2005-10-31 Astrazeneca Ab Derivados de quinazolina como inibidores de angiogenese
US6258820B1 (en) 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
ES2231179T3 (es) 1999-04-12 2005-05-16 Aventis Pharma Limited Compuestos de heteroarilo biciclicos sustituidos como antagonistas de la integrina.
JP2004511479A (ja) 2000-10-13 2004-04-15 アストラゼネカ アクチボラグ キナゾリン誘導体
AU9598601A (en) 2000-10-20 2002-04-29 Eisai Co Ltd Nitrogenous aromatic ring compounds
AU2002313249B2 (en) 2001-06-22 2008-08-21 Kirin Pharma Kabushiki Kaisha Quinoline derivative and quinazoline derivate inhibiting self-phosphorylation of hepatocytus proliferator receptor, and medicinal composition containing the same
GB0126433D0 (en) 2001-11-03 2002-01-02 Astrazeneca Ab Compounds
US20050043336A1 (en) 2001-11-03 2005-02-24 Hennequin Laurent Francois Andre Quinazoline derivatives as antitumor agents
SI1474420T1 (sl) 2002-02-01 2012-06-29 Astrazeneca Ab Spojine kinazolina
US7645878B2 (en) 2002-03-22 2010-01-12 Bayer Healthcare Llc Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
WO2003082272A1 (en) 2002-03-29 2003-10-09 Chiron Corporation Substituted benzazoles and use thereof as raf kinase inhibitors
WO2004018430A1 (ja) 2002-08-23 2004-03-04 Kirin Beer Kabushiki Kaisha TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物
WO2004078114A2 (en) 2003-02-28 2004-09-16 Encysive Pharmaceuticals Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-ii receptor antagonists.
US7320989B2 (en) 2003-02-28 2008-01-22 Encysive Pharmaceuticals, Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
US7531553B2 (en) 2003-03-21 2009-05-12 Amgen Inc. Heterocyclic compounds and methods of use
GB0310401D0 (en) 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
US7312330B2 (en) 2003-12-24 2007-12-25 Renovis, Inc. Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
GEP20084439B (en) 2004-01-23 2008-07-25 Amgen Inc Nitrogen-containing heterocyclic derivatives and pharmaceutical use thereof
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use

Also Published As

Publication number Publication date
EP2220078A2 (en) 2010-08-25
JP5343082B2 (ja) 2013-11-13
AU2008319366A1 (en) 2009-05-07
WO2009058267A3 (en) 2010-06-10
MX2010004620A (es) 2010-07-28
CA2703257A1 (en) 2009-05-07
CA2703257C (en) 2013-02-19
US7795254B2 (en) 2010-09-14
EP2220078B1 (en) 2013-05-22
AU2008319366B2 (en) 2012-03-01
JP2011502147A (ja) 2011-01-20
US20090149454A1 (en) 2009-06-11
WO2009058267A2 (en) 2009-05-07

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