ES2417009T3 - Derivados de benzomorfolina y métodos de uso - Google Patents

Derivados de benzomorfolina y métodos de uso Download PDF

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Publication number
ES2417009T3
ES2417009T3 ES08845711T ES08845711T ES2417009T3 ES 2417009 T3 ES2417009 T3 ES 2417009T3 ES 08845711 T ES08845711 T ES 08845711T ES 08845711 T ES08845711 T ES 08845711T ES 2417009 T3 ES2417009 T3 ES 2417009T3
Authority
ES
Spain
Prior art keywords
compound
usa
formula
vegf
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08845711T
Other languages
English (en)
Spanish (es)
Inventor
Jean-Christophe Harmange
Matthew W. Martin
Yohannes Teffera
Raju Subramanian
Ryan White
Roger Zanon
Jay Larrow
Joseph F. Payack
Mina Dilmeghani Seran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ES2417009T3 publication Critical patent/ES2417009T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES08845711T 2007-10-29 2008-10-28 Derivados de benzomorfolina y métodos de uso Active ES2417009T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94807P 2007-10-29 2007-10-29
US948P 2007-10-29
PCT/US2008/012224 WO2009058267A2 (en) 2007-10-29 2008-10-28 Benzomorpholine derivatives and methods of use

Publications (1)

Publication Number Publication Date
ES2417009T3 true ES2417009T3 (es) 2013-08-05

Family

ID=40394086

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08845711T Active ES2417009T3 (es) 2007-10-29 2008-10-28 Derivados de benzomorfolina y métodos de uso

Country Status (8)

Country Link
US (1) US7795254B2 (OSRAM)
EP (1) EP2220078B1 (OSRAM)
JP (1) JP5343082B2 (OSRAM)
AU (1) AU2008319366B2 (OSRAM)
CA (1) CA2703257C (OSRAM)
ES (1) ES2417009T3 (OSRAM)
MX (1) MX2010004620A (OSRAM)
WO (1) WO2009058267A2 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH684182A5 (de) 1991-10-15 1994-07-29 Escher Wyss Ag Rotationsdruckmaschine.
CN102892762B (zh) * 2010-05-19 2016-04-20 桑多斯股份公司 制备泊沙康唑中间体
BR112012029225B1 (pt) 2010-05-19 2020-10-27 Sandoz Ag processo para a preparação de um composto quiral, composto quiral e uso de um composto quiral
MX2012013331A (es) 2010-05-19 2013-02-01 Sandoz Ag Purificacion de posaconazol y de intermediarios de posaconazol.
CA2838051C (en) 2011-06-16 2019-09-24 Sandoz Ag Process for the preparation of a chiral compound

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755332A (en) 1971-07-01 1973-08-28 Ciba Geigy Corp Substituted 4 indazolaminoquinolines
US4916135A (en) 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB9323290D0 (en) 1992-12-10 1994-01-05 Zeneca Ltd Quinazoline derivatives
WO1996023774A1 (en) 1995-01-31 1996-08-08 Zenyaku Kogyo Kabushiki Kaisha Thioquinoline derivatives
GB9505702D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd Fungicidal compounds
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
US6143764A (en) 1995-11-07 2000-11-07 Kirin Beer Kabushiki Kaisha Quinoline and quinazoline derivatives inhibiting platelet-derived growth factor receptor autophosphorylation and pharmaceutical compositions containing the same
EP0802914B1 (en) 1995-11-14 2001-06-06 PHARMACIA & UPJOHN S.p.A. Aryl- and heteroaryl- purine and pyridopyrimidine derivatives
GB9603095D0 (en) 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
DE19614718A1 (de) 1996-04-15 1997-10-16 Hoechst Schering Agrevo Gmbh Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung, und ihre Verwendung als Schädlingsbekämpfungsmittel
GB9800575D0 (en) 1998-01-12 1998-03-11 Glaxo Group Ltd Heterocyclic compounds
AU3534699A (en) 1998-04-23 1999-11-08 Takeda Chemical Industries Ltd. Naphthalene derivatives, their production and use
HUP0103386A3 (en) 1998-08-21 2002-07-29 Parker Hughes Inst St Paul Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
EE05345B1 (et) 1999-02-10 2010-10-15 Astrazeneca Ab Kinasoliini derivaadid angiogeneesi inhibiitoritena
US6258820B1 (en) 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
EE200100528A (et) 1999-04-12 2003-02-17 Aventis Pharma Limited Asendatud bitsükliline heteroarüülühend, seda sisaldav farmatseutiline kompositsioon ning nende raviotstarbeline kasutamine
JP2004511479A (ja) 2000-10-13 2004-04-15 アストラゼネカ アクチボラグ キナゾリン誘導体
HU230302B1 (hu) 2000-10-20 2015-12-28 Eisai R&D Management Co., Ltd. Nitrogéntartalmú aromás származékok és ezeket tartalmazó gyógyászati készítmények
DE60233736D1 (de) 2001-06-22 2009-10-29 Kirin Pharma K K Chinolinderivat und chinazolinderivat, die die selbstphosphorylierung des hepatocytus-proliferator-rezeptors hemmen, und diese enthaltende medizinische zusammensetzung
WO2003040108A1 (en) 2001-11-03 2003-05-15 Astrazeneca Ab Quinazoline derivatives as antitumor agents
GB0126433D0 (en) 2001-11-03 2002-01-02 Astrazeneca Ab Compounds
MXPA04007459A (es) 2002-02-01 2005-09-08 Astrazeneca Ab Compuestos de quinazolina.
US7645878B2 (en) 2002-03-22 2010-01-12 Bayer Healthcare Llc Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
DK1499311T3 (da) 2002-03-29 2010-03-08 Novartis Vaccines & Diagnostic Substituerede benzaboler og anvendelse deraf som RAF-kinaseinhibitorer
KR100942073B1 (ko) 2002-08-23 2010-02-12 기린 홀딩스 가부시키가이샤 TGF β 저해 활성을 갖는 화합물 및 그것을 포함하여 이루어지는 의약 조성물
WO2004078114A2 (en) 2003-02-28 2004-09-16 Encysive Pharmaceuticals Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-ii receptor antagonists.
US7320989B2 (en) 2003-02-28 2008-01-22 Encysive Pharmaceuticals, Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
US7531553B2 (en) 2003-03-21 2009-05-12 Amgen Inc. Heterocyclic compounds and methods of use
GB0310401D0 (en) 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
US7312330B2 (en) 2003-12-24 2007-12-25 Renovis, Inc. Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
UA86614C2 (ru) * 2004-01-23 2009-05-12 Амген Инк Соединение, которое имеет активность ингибитора киназ, фармацевтическая композиция, которая включает указанное соединение, и их применение для приготовления лекарственного препарата
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use

Also Published As

Publication number Publication date
WO2009058267A3 (en) 2010-06-10
EP2220078B1 (en) 2013-05-22
AU2008319366B2 (en) 2012-03-01
US20090149454A1 (en) 2009-06-11
CA2703257C (en) 2013-02-19
JP2011502147A (ja) 2011-01-20
AU2008319366A1 (en) 2009-05-07
US7795254B2 (en) 2010-09-14
JP5343082B2 (ja) 2013-11-13
WO2009058267A2 (en) 2009-05-07
CA2703257A1 (en) 2009-05-07
MX2010004620A (es) 2010-07-28
EP2220078A2 (en) 2010-08-25

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