ES2392915B1 - Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos - Google Patents

Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos

Info

Publication number
ES2392915B1
ES2392915B1 ES201100639A ES201100639A ES2392915B1 ES 2392915 B1 ES2392915 B1 ES 2392915B1 ES 201100639 A ES201100639 A ES 201100639A ES 201100639 A ES201100639 A ES 201100639A ES 2392915 B1 ES2392915 B1 ES 2392915B1
Authority
ES
Spain
Prior art keywords
polyphenolic
selenium
compounds containing
containing sulfur
bioactive compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES201100639A
Other languages
English (en)
Other versions
ES2392915A1 (es
Inventor
Guzman Jose Maria Fernandez-Bolanos
Castilla Ines Maya
Garcia Maria Angeles Lopez
Guzman Juan Fernandez-Bolanos
Gurierrez Guillermo Rodriguez
Carretero Antonio Gomez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Sevilla
Instituto de la Grasa CSIC
Original Assignee
Universidad de Sevilla
Instituto de la Grasa CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Sevilla, Instituto de la Grasa CSIC filed Critical Universidad de Sevilla
Priority to ES201100639A priority Critical patent/ES2392915B1/es
Priority to PCT/ES2012/000151 priority patent/WO2012164118A1/es
Publication of ES2392915A1 publication Critical patent/ES2392915A1/es
Application granted granted Critical
Publication of ES2392915B1 publication Critical patent/ES2392915B1/es
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/16Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/02Thiols having mercapto groups bound to acyclic carbon atoms
    • C07C321/10Thiols having mercapto groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/12Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
    • C07C321/20Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/06Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00Compounds containing selenium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES201100639A 2011-06-03 2011-06-03 Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos Expired - Fee Related ES2392915B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES201100639A ES2392915B1 (es) 2011-06-03 2011-06-03 Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos
PCT/ES2012/000151 WO2012164118A1 (es) 2011-06-03 2012-06-01 Compuestos bioactivos polifenólicos conteniendo azufre o selenio y sus usos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201100639A ES2392915B1 (es) 2011-06-03 2011-06-03 Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos

Publications (2)

Publication Number Publication Date
ES2392915A1 ES2392915A1 (es) 2012-12-14
ES2392915B1 true ES2392915B1 (es) 2013-09-13

Family

ID=47222364

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201100639A Expired - Fee Related ES2392915B1 (es) 2011-06-03 2011-06-03 Compuestos bioactivos polifenolicos conteniendo azufre o selenio y sus usos

Country Status (2)

Country Link
ES (1) ES2392915B1 (es)
WO (1) WO2012164118A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104073544A (zh) * 2013-03-25 2014-10-01 上海爱启生态科技有限公司 一种有机硒化合物的制备方法
CN104119260A (zh) * 2013-04-25 2014-10-29 上海爱启生态科技有限公司 以碱金属离子硒配合物为功能团的多酚硒化合物
ES2539637B1 (es) * 2013-09-24 2016-02-05 Universidad De Sevilla Nuevos antiiflamatorios basados en polifenoles del olivo
CN104892558A (zh) * 2014-03-06 2015-09-09 上海爱启生态科技有限公司 一种高硒含量硒化茶多酚制剂
ES2556151B2 (es) * 2014-06-30 2016-04-22 Universidad De Sevilla Uso como antioxidantes de compuestos organoselénicos fenólicos y sus composiciones
WO2016033105A1 (en) 2014-08-29 2016-03-03 The Board Of Regents Of The University Of Texas System Novel capsazepine analogs for the treatment of cancer and other proliferative diseases
RU2586067C1 (ru) * 2015-04-20 2016-06-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "НОВОСИБИРСКИЙ ГОСУДАРСТВЕННЫЙ ПЕДАГОГИЧЕСКИЙ УНИВЕРСИТЕТ" (ФГБОУ ВПО "НГПУ") Бис-(3,5-ди-трет-бутил-4-гидроксифенил)пропил)селенид, обладающий антиоксидантной и гипогликемической активностью
RU2713183C1 (ru) * 2019-08-05 2020-02-04 Федеральное государственное бюджетное образовательное учреждение высшего образования "Новосибирский государственный педагогический университет" Одностадийный способ синтеза бис(3,5-диалкил-4-гидроксибензил)селенидов
IT202100027827A1 (it) * 2021-10-29 2023-04-29 Univ Degli Studi Di Firenze Derivati del carbamoselenoile come agenti antinfettivi

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016318A1 (en) * 2000-08-21 2002-02-28 Pacific Corporation Novel thiourea derivatives and the pharmaceutical compositions containing the same
AU1502802A (en) * 2000-10-17 2002-04-29 Applied Research Systems Method of operating a computer system to perform a discrete substructural analysis
RU2008141686A (ru) * 2006-03-21 2010-04-27 Те Юропиан Моулекьюлар Байолоджи Лаборатори (De) Агенты, нарушающие клеточную репликацию, и их применение для ингибирования патологических состояний

Also Published As

Publication number Publication date
ES2392915A1 (es) 2012-12-14
WO2012164118A1 (es) 2012-12-06

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