CO7091181A2 - Compuestos heterociclicos y sus usos - Google Patents

Compuestos heterociclicos y sus usos

Info

Publication number
CO7091181A2
CO7091181A2 CO14222148A CO14222148A CO7091181A2 CO 7091181 A2 CO7091181 A2 CO 7091181A2 CO 14222148 A CO14222148 A CO 14222148A CO 14222148 A CO14222148 A CO 14222148A CO 7091181 A2 CO7091181 A2 CO 7091181A2
Authority
CO
Colombia
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
CO14222148A
Other languages
English (en)
Inventor
Minna Hue Thanh Rui
Timothy D Cushing
Lopez De Turiso Felix Gonzalez
Xiaolin Hao
Brian Lucas
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CO7091181A2 publication Critical patent/CO7091181A2/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
CO14222148A 2012-04-04 2014-10-07 Compuestos heterociclicos y sus usos CO7091181A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261620270P 2012-04-04 2012-04-04

Publications (1)

Publication Number Publication Date
CO7091181A2 true CO7091181A2 (es) 2014-10-21

Family

ID=48142975

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14222148A CO7091181A2 (es) 2012-04-04 2014-10-07 Compuestos heterociclicos y sus usos

Country Status (31)

Country Link
US (2) US8716290B2 (es)
EP (1) EP2834231B1 (es)
JP (1) JP2015512451A (es)
KR (1) KR20140139547A (es)
CN (1) CN104395305A (es)
AP (1) AP3611A (es)
AU (1) AU2013243506A1 (es)
CA (1) CA2869413A1 (es)
CL (1) CL2014002686A1 (es)
CO (1) CO7091181A2 (es)
CR (1) CR20140503A (es)
CY (1) CY1117487T1 (es)
DK (1) DK2834231T3 (es)
EA (1) EA201491823A1 (es)
ES (1) ES2577109T3 (es)
HR (1) HRP20160352T1 (es)
HU (1) HUE028762T2 (es)
IL (1) IL234822A0 (es)
MA (1) MA37472A1 (es)
ME (1) ME02473B (es)
MX (1) MX2014011970A (es)
PE (1) PE20142457A1 (es)
PH (1) PH12014502246A1 (es)
PL (1) PL2834231T3 (es)
RS (1) RS54716B1 (es)
SG (1) SG11201406316VA (es)
SI (1) SI2834231T1 (es)
SM (1) SMT201600211B (es)
TN (1) TN2014000412A1 (es)
WO (1) WO2013152150A1 (es)
ZA (1) ZA201407037B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2640715A1 (en) * 2010-11-17 2013-09-25 Amgen Inc. Quinoline derivatives as pik3 inhibitors
SI2834231T1 (sl) * 2012-04-04 2016-09-30 AmgenInc. Heterociklične spojine in njihove uporabe
WO2015171725A1 (en) 2014-05-06 2015-11-12 Amgen Inc. Hydrate, crystalline hydrate and crystalline anhydrate forms of n-((1s)-1-(7-fluoro-2-(2-pyridinyl)-3-quinolinyl)ethyl)-9h-purin-6-amine, pharmaceutical compositions containing them and methods for treating cancer.
UA115296C2 (uk) 2014-07-04 2017-10-10 Люпін Лімітед Хінолізинонові похідні як інгібітори pi3k
US9637488B2 (en) 2015-01-29 2017-05-02 Fuqiang Ruan Heterocyclic compounds as inhibitors of class I PI3KS
CN108290898B (zh) * 2016-03-05 2020-09-08 杭州征祥医药有限公司 作为磷脂酰肌醇3-激酶抑制剂的喹啉类似物
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT72878B (en) 1980-04-24 1983-03-29 Merck & Co Inc Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents
US6043062A (en) 1995-02-17 2000-03-28 The Regents Of The University Of California Constitutively active phosphatidylinositol 3-kinase and uses thereof
GB9611460D0 (en) 1996-06-01 1996-08-07 Ludwig Inst Cancer Res Novel lipid kinase
US5858753A (en) 1996-11-25 1999-01-12 Icos Corporation Lipid kinase
US5822910A (en) 1997-10-02 1998-10-20 Shewmake; I. W. Fishing line tensioning device
ATE434614T1 (de) * 2004-06-28 2009-07-15 Bayer Schering Pharma Ag 4,6-disubstitutierte pyrimidine und deren verwendung als proteinkinase-hemmer
CA2680853C (en) * 2007-03-23 2012-07-17 Amgen Inc. 3- substituted quinoline or quinoxaline derivatives and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors
US8399483B2 (en) * 2007-12-21 2013-03-19 Ucb Pharma S.A. Quinoxaline and quinoline derivatives as kinase inhibitors
AU2009322187B2 (en) * 2008-12-04 2015-02-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of CNS disorders
BRPI1016150A2 (pt) * 2009-06-25 2016-04-19 Amgen Inc compostos heterocíclicos e seus usos.
CA2784566A1 (en) * 2009-12-18 2011-06-23 Amgen Inc. Heterocyclic compounds and their uses
JP2013533884A (ja) * 2010-07-02 2013-08-29 アムジエン・インコーポレーテツド Pi3k活性阻害剤としての複素環化合物およびそれらの使用
SI2834231T1 (sl) * 2012-04-04 2016-09-30 AmgenInc. Heterociklične spojine in njihove uporabe

Also Published As

Publication number Publication date
EP2834231B1 (en) 2016-03-30
WO2013152150A1 (en) 2013-10-10
CL2014002686A1 (es) 2015-05-08
SMT201600211B (it) 2016-08-31
JP2015512451A (ja) 2015-04-27
KR20140139547A (ko) 2014-12-05
TN2014000412A1 (en) 2015-12-21
US20130267524A1 (en) 2013-10-10
US8716290B2 (en) 2014-05-06
EA201491823A1 (ru) 2015-01-30
US20140206694A1 (en) 2014-07-24
PL2834231T3 (pl) 2016-07-29
ME02473B (me) 2017-02-20
PE20142457A1 (es) 2015-02-07
ES2577109T3 (es) 2016-07-13
CY1117487T1 (el) 2017-04-26
AP2014007979A0 (en) 2014-09-30
HRP20160352T1 (hr) 2016-05-06
AP3611A (en) 2016-02-29
US8835432B2 (en) 2014-09-16
ZA201407037B (en) 2015-11-25
IL234822A0 (en) 2014-12-31
EP2834231A1 (en) 2015-02-11
CR20140503A (es) 2015-03-06
HUE028762T2 (en) 2016-12-28
RS54716B1 (en) 2016-08-31
CN104395305A (zh) 2015-03-04
MA37472A1 (fr) 2016-09-30
CA2869413A1 (en) 2013-10-10
SI2834231T1 (sl) 2016-09-30
SG11201406316VA (en) 2014-11-27
PH12014502246A1 (en) 2014-12-15
MX2014011970A (es) 2015-05-12
AU2013243506A1 (en) 2014-10-09
DK2834231T3 (en) 2016-04-18

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