ES2377489T3 - Péptido derivado del receptor 3 de neurotensina y utilización en el tratamiento de enfermedades psiquiátricas - Google Patents

Péptido derivado del receptor 3 de neurotensina y utilización en el tratamiento de enfermedades psiquiátricas Download PDF

Info

Publication number
ES2377489T3
ES2377489T3 ES08872504T ES08872504T ES2377489T3 ES 2377489 T3 ES2377489 T3 ES 2377489T3 ES 08872504 T ES08872504 T ES 08872504T ES 08872504 T ES08872504 T ES 08872504T ES 2377489 T3 ES2377489 T3 ES 2377489T3
Authority
ES
Spain
Prior art keywords
peptide
trek
mice
depression
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08872504T
Other languages
English (en)
Spanish (es)
Inventor
Jean Mazella
Olivier Petrault
Marc Borsotto
Catherine Heurteaux
Catherine Widmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite de Nice Sophia Antipolis UNSA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite de Nice Sophia Antipolis UNSA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite de Nice Sophia Antipolis UNSA filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of ES2377489T3 publication Critical patent/ES2377489T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES08872504T 2007-12-21 2008-12-18 Péptido derivado del receptor 3 de neurotensina y utilización en el tratamiento de enfermedades psiquiátricas Active ES2377489T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07291602A EP2077278A1 (fr) 2007-12-21 2007-12-21 Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques
EP07291602 2007-12-21
PCT/FR2008/001784 WO2009103898A1 (fr) 2007-12-21 2008-12-18 Peptide derive du recepteur 3 de la neurotensine et utilisation dans le traitement de maladies psychiatriques

Publications (1)

Publication Number Publication Date
ES2377489T3 true ES2377489T3 (es) 2012-03-28

Family

ID=39304741

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08872504T Active ES2377489T3 (es) 2007-12-21 2008-12-18 Péptido derivado del receptor 3 de neurotensina y utilización en el tratamiento de enfermedades psiquiátricas

Country Status (7)

Country Link
US (1) US8252748B2 (https=)
EP (2) EP2077278A1 (https=)
JP (1) JP5487117B2 (https=)
AT (1) ATE535543T1 (https=)
CA (1) CA2709907C (https=)
ES (1) ES2377489T3 (https=)
WO (1) WO2009103898A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077278A1 (fr) * 2007-12-21 2009-07-08 Centre National de la Recherche Scientifique (CNRS) Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques
EP3099313B1 (en) * 2014-01-27 2021-04-21 Centre National De La Recherche Scientifique Retro-inverso analogs of spadin display increased antidepressant effects
SI3380495T1 (sl) 2015-11-24 2022-01-31 Transfert Plus, S.E.C. Peptidne spojine in peptidni konjugati za zdravljenje raka z receptorsko posredovano kemoterapijo
FR3057266B1 (fr) * 2016-10-11 2021-05-21 Centre Nat Rech Scient Peptides derives du propeptide ntsr3 et leur utilisation dans le traitement de la depression
FR3057267A1 (fr) * 2016-10-11 2018-04-13 Centre National De La Recherche Scientifique - Cnrs - Procede de diagnostic/determination de l'efficacite de traitement de la depression
JP7719060B2 (ja) * 2019-10-22 2025-08-05 ジェネトン キメラポリペプチド及びその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051485A1 (en) * 1998-01-27 2000-11-15 Smithkline Beecham Plc Trek-1 like two pore potassium channel
EP1891966B1 (en) * 2002-12-20 2012-02-15 H. Lundbeck A/S Modulation of activity of neurotrophins; screening method
EP2077278A1 (fr) 2007-12-21 2009-07-08 Centre National de la Recherche Scientifique (CNRS) Peptide dérivé du récepteur 3 de la neurotensine et utilisation dans le traitemement de maladies psychiatriques

Also Published As

Publication number Publication date
CA2709907A1 (fr) 2009-08-27
EP2229408B1 (fr) 2011-11-30
EP2077278A1 (fr) 2009-07-08
US8252748B2 (en) 2012-08-28
JP5487117B2 (ja) 2014-05-07
WO2009103898A1 (fr) 2009-08-27
CA2709907C (fr) 2016-11-08
EP2229408A1 (fr) 2010-09-22
JP2011505864A (ja) 2011-03-03
ATE535543T1 (de) 2011-12-15
US20110237515A1 (en) 2011-09-29

Similar Documents

Publication Publication Date Title
Odaira et al. Mechanisms underpinning AMP-activated protein kinase-related effects on behavior and hippocampal neurogenesis in an animal model of depression
JP7693290B2 (ja) Larファミリーホスファターゼの活性を阻害する組成物及び方法
CA2910652C (en) Tafa4 compounds and uses thereof for treating pain
ES2377489T3 (es) Péptido derivado del receptor 3 de neurotensina y utilización en el tratamiento de enfermedades psiquiátricas
Latouche et al. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes
Xu et al. Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine
AU2016215080B2 (en) Methods and compositions for improved cognition
US20250163126A1 (en) Artificial synapses
ES2745335T3 (es) Proteínas de fusión TATk-CDKL5, composiciones, formulaciones y uso de estas
Cheng et al. Transcranial direct-current stimulation protects against cerebral ischemia-reperfusion injury through regulating Cezanne-dependent signaling
JP2020023508A (ja) spadinのレトロ−インベルソ類似体は増大された抗うつ作用を示す
CN101454341B (zh) 表面核仁素的多价合成配体在治疗癌症或发炎中的用途
JP2017507655A5 (https=)
JP2019522989A (ja) TATκ−CDKL5融合タンパク質、組成物、製剤、及びそれらの使用
ES2186596T3 (es) Uso de inhibidores de la interleucina-18 para inhibir metastasis tumorales.
ES2617309T3 (es) Métodos y ensayos de tratamiento de sujetos con eliminación, mutación o expresión reducida de SHANK3
CN115006534A (zh) 钾离子通道Kir4.1抑制剂治疗抑郁症的用途和药物组合物
ES2569552T3 (es) Composiciones de péptido de MNTF y métodos de uso
ES2677564T3 (es) Método y composición farmacéutica para su uso en el tratamiento de trastornos neurodegenerativos
US8481486B2 (en) Methods of treating neurological diseases by regulating migration of neuroblasts in the adult nervous system with tenascin-R
ES2965080T3 (es) Péptidos derivados del propéptido NTSR3 y su uso en el tratamiento de la depresión
US20110189194A1 (en) Use of cd95 inhibitors for the treatment of inflammatory disorders
Yoon et al. Shifting hippocampal excitation/inhibition balance modifies despair-like behavior in mice
WO2026056985A1 (zh) 抑郁症的治疗方法和药物组合物
Class et al. Patent application title: TAFA4 COMPOUNDS AND USES THEREOF FOR TREATING PAIN Inventors: Aziz Moqrich (Marseille, FR) Marie-Claire Delfini (Marseille, FR) Annabelle Mantilleri (Apt, FR)