ES2340708T3 - Tratamiento de esclerosis lateral amiotrofica con pirimetamina y analogos. - Google Patents

Tratamiento de esclerosis lateral amiotrofica con pirimetamina y analogos. Download PDF

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Publication number
ES2340708T3
ES2340708T3 ES06736552T ES06736552T ES2340708T3 ES 2340708 T3 ES2340708 T3 ES 2340708T3 ES 06736552 T ES06736552 T ES 06736552T ES 06736552 T ES06736552 T ES 06736552T ES 2340708 T3 ES2340708 T3 ES 2340708T3
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ES
Spain
Prior art keywords
sod
pyrimethamine
protein
als
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Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06736552T
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English (en)
Spanish (es)
Inventor
Sean Scott
Daniel Benjamin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALSGEN Inc
Original Assignee
ALSGEN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALSGEN Inc filed Critical ALSGEN Inc
Application granted granted Critical
Publication of ES2340708T3 publication Critical patent/ES2340708T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyurethanes Or Polyureas (AREA)
ES06736552T 2005-03-04 2006-03-01 Tratamiento de esclerosis lateral amiotrofica con pirimetamina y analogos. Active ES2340708T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65850505P 2005-03-04 2005-03-04
US658505P 2005-03-04

Publications (1)

Publication Number Publication Date
ES2340708T3 true ES2340708T3 (es) 2010-06-08

Family

ID=36953835

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06736552T Active ES2340708T3 (es) 2005-03-04 2006-03-01 Tratamiento de esclerosis lateral amiotrofica con pirimetamina y analogos.

Country Status (10)

Country Link
US (1) US20060211645A1 (cg-RX-API-DMAC7.html)
EP (1) EP1917017B1 (cg-RX-API-DMAC7.html)
JP (1) JP2008531710A (cg-RX-API-DMAC7.html)
CN (1) CN101184493A (cg-RX-API-DMAC7.html)
AT (1) ATE456953T1 (cg-RX-API-DMAC7.html)
AU (1) AU2006220919A1 (cg-RX-API-DMAC7.html)
CA (1) CA2600067A1 (cg-RX-API-DMAC7.html)
DE (1) DE602006012115D1 (cg-RX-API-DMAC7.html)
ES (1) ES2340708T3 (cg-RX-API-DMAC7.html)
WO (1) WO2006096405A2 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101232888A (zh) * 2005-03-04 2008-07-30 阿尔斯根公司 用炔诺酮及其类似物治疗肌萎缩性侧索硬化
US20070135437A1 (en) * 2005-03-04 2007-06-14 Alsgen, Inc. Modulation of neurodegenerative diseases
WO2006096415A2 (en) * 2005-03-04 2006-09-14 Alsgen, Llc Modulation of neurodegenerative diseases through the estrogen receptor
US20080153094A1 (en) * 2006-10-13 2008-06-26 Minor James M Reduction of nonspecific binding in nucleic acid assays and nucleic acid synthesis reactions
WO2009067493A2 (en) * 2007-11-19 2009-05-28 Envivo Pharmaceuticals, Inc. 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
US8217064B2 (en) 2007-12-20 2012-07-10 Envivo Pharmaceuticals, Inc. Tetrasubstituted benzenes
AR076601A1 (es) 2009-05-21 2011-06-22 Chlorion Pharma Inc Pirimidinas como agentes terapeuticos
GB201015079D0 (en) 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
SI2718270T1 (sl) 2011-06-10 2022-11-30 Merck Patent Gmbh Sestavki in postopki za proizvodnjo pirimidinskih in piridinskih spojin z BTK inhibitorno aktivnostjo
CN104398517A (zh) * 2014-11-28 2015-03-11 四川大学 乙胺嘧啶的新用途及治疗肿瘤的药物组合物
KR20210056931A (ko) * 2019-11-11 2021-05-20 에스케이케미칼 주식회사 피리메타민을 유효성분으로 포함하는 면역 관련 질환의 치료 또는 예방용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231170A (en) * 1986-08-27 1993-07-27 Paul Averback Antibodies to dense microspheres
US5866562A (en) * 1996-10-25 1999-02-02 Bayer Aktiengesellschaft Ring-bridged bis-quinolines
US7442629B2 (en) * 2004-09-24 2008-10-28 President & Fellows Of Harvard College Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate
KR101031720B1 (ko) * 2001-11-28 2011-04-29 비티지 인터내셔널 리미티드 질소함유 헤테로아릴 화합물을 함유하는 알츠하이머병의예방약 또는 치료약 또는 아밀로이드 단백질 섬유화억제제
KR20040099324A (ko) * 2002-03-13 2004-11-26 유로-셀티큐 에스.에이. 아릴 치환된 피리미딘 및 이것의 용도
US20050026823A1 (en) * 2003-06-20 2005-02-03 Biomarin Pharmaceutical Inc. Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues
CN101232888A (zh) * 2005-03-04 2008-07-30 阿尔斯根公司 用炔诺酮及其类似物治疗肌萎缩性侧索硬化
US20070135437A1 (en) * 2005-03-04 2007-06-14 Alsgen, Inc. Modulation of neurodegenerative diseases

Also Published As

Publication number Publication date
WO2006096405A2 (en) 2006-09-14
EP1917017B1 (en) 2010-02-03
AU2006220919A1 (en) 2006-09-14
WO2006096405A8 (en) 2008-04-10
JP2008531710A (ja) 2008-08-14
DE602006012115D1 (de) 2010-03-25
US20060211645A1 (en) 2006-09-21
EP1917017A2 (en) 2008-05-07
WO2006096405A3 (en) 2007-05-18
CA2600067A1 (en) 2006-09-14
CN101184493A (zh) 2008-05-21
ATE456953T1 (de) 2010-02-15

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