ES229417A1 - A method of preparation of compounds with antimalaric activity (Machine-translation by Google Translate, not legally binding)
- Google Patents
A method of preparation of compounds with antimalaric activity (Machine-translation by Google Translate, not legally binding)
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Wellcome Foundation Ltd
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Wellcome Foundation Ltd
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Priority claimed from GB1804955Aexternal-prioritypatent/GB790202A/en
Application filed by Wellcome Foundation LtdfiledCriticalWellcome Foundation Ltd
Publication of ES229417A1publicationCriticalpatent/ES229417A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Method of preparation of compounds with antimalarial activity of formula (I) and acid edition salts thereof or of formula (II): ** (see formula) ** in which formulas one of the groups R1 and R2 and one of the groups R3 and R4 are hydroxy groups the other of the groups R1 and R2 and of the groups R3 and R4 are groups represented by the formula -CH2 NHR5 where R5 is a linear or branched alkyl group having 1 to 8 carbon atoms or a cycloalkyl group having 5 to 7 ring carbon atoms; X and Y represent the group CH2 NR5 -CH2 -O- where R5 has the meaning given above characterized in that an appropriate baphthalen-diol is reacted with formaldehyde and an amine R5 NH2 in which R5 has the meaning given above, thus obtaining a compound of formula (11) AND in which to obtain of the compound of formula (I) the compound of formula (II) is treated with an acid to give said compound of formula (I). (Machine-translation by Google Translate, not legally binding)
ES0229417A1955-06-221956-06-22A method of preparation of compounds with antimalaric activity (Machine-translation by Google Translate, not legally binding)
ExpiredES229417A1
(en)
Procedure for the preparation of new compounds of 1,4-benzodioxane and 1,5-benzodioxane and of 1,5-benzodioxepane (Machine-translation by Google Translate, not legally binding)
Procedure for the preparation of N-substituted piperidine derivatives and their use as stabilizers. (Machine-translation by Google Translate, not legally binding)