ES2276942T3 - Combinacion de un inhibidor de pde4 y tiotropio o un derivado del mismo para tratar vias respiratorias obstructivas y otras enfermedades inflamatorias. - Google Patents
Combinacion de un inhibidor de pde4 y tiotropio o un derivado del mismo para tratar vias respiratorias obstructivas y otras enfermedades inflamatorias. Download PDFInfo
- Publication number
- ES2276942T3 ES2276942T3 ES02740638T ES02740638T ES2276942T3 ES 2276942 T3 ES2276942 T3 ES 2276942T3 ES 02740638 T ES02740638 T ES 02740638T ES 02740638 T ES02740638 T ES 02740638T ES 2276942 T3 ES2276942 T3 ES 2276942T3
- Authority
- ES
- Spain
- Prior art keywords
- triazolo
- pyrazolo
- dihydro
- pyridine
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 title claims 2
- 101100082610 Plasmodium falciparum (isolate 3D7) PDEdelta gene Proteins 0.000 title claims 2
- 239000003814 drug Substances 0.000 claims abstract description 133
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Landscapes
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- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29355501P | 2001-05-25 | 2001-05-25 | |
| US293555P | 2001-05-25 | ||
| US30384501P | 2001-07-09 | 2001-07-09 | |
| US303845P | 2001-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2276942T3 true ES2276942T3 (es) | 2007-07-01 |
Family
ID=26968011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02740638T Expired - Lifetime ES2276942T3 (es) | 2001-05-25 | 2002-05-23 | Combinacion de un inhibidor de pde4 y tiotropio o un derivado del mismo para tratar vias respiratorias obstructivas y otras enfermedades inflamatorias. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1397135B1 (enExample) |
| JP (1) | JP2004530705A (enExample) |
| AT (1) | ATE347361T1 (enExample) |
| AU (1) | AU2002314102A1 (enExample) |
| CA (1) | CA2448363A1 (enExample) |
| DE (1) | DE60216588T2 (enExample) |
| ES (1) | ES2276942T3 (enExample) |
| MX (1) | MXPA03010791A (enExample) |
| WO (1) | WO2002096423A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| ATE384529T1 (de) * | 2003-03-28 | 2008-02-15 | Nycomed Gmbh | Synergistische kombination enthaltend roflumilast und einen anticholinergischen wirkstoff ausgewählt aus tiotropiumsalzen für die behandlung von atemwegserkrankungen |
| BRPI0409492A (pt) * | 2003-04-18 | 2006-05-02 | Pharmacia & Up John Company Ll | terapias de combinação |
| WO2004103407A2 (en) * | 2003-05-22 | 2004-12-02 | Altana Pharma Ag | Composition comprising a pde4 inhibitor and a pde5 inhibitor |
| EP1651222A1 (en) * | 2003-07-29 | 2006-05-03 | Boehringer Ingelheim International Gmbh | Medicaments comprising pde iv inhibitors and an anticholinergic for treating respiratory disorders |
| EP1504756A1 (en) * | 2003-08-06 | 2005-02-09 | Kyowa Hakko Kogyo Co., Ltd | Medicament compositions comprising a heterocyclic compound and an anticholinergic |
| PL1713471T3 (pl) * | 2004-02-06 | 2012-06-29 | Meda Pharma Gmbh & Co Kg | Kombinacja środków antycholinergicznych i inhibitorów fosfodiesterazy typu 4 do leczenia chorób oddechowych |
| RU2006132043A (ru) * | 2004-02-06 | 2008-03-20 | МЕДА Фарма ГмбХ унд Ко.КГ (DE) | Комбинация и фармацевтический препарат для лечения ринита |
| AU2005210085B2 (en) | 2004-02-06 | 2010-06-24 | Meda Pharma Gmbh & Co. Kg | The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and COPD |
| US7507745B2 (en) | 2004-02-20 | 2009-03-24 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins |
| JP2007523117A (ja) * | 2004-02-20 | 2007-08-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗コリン作用薬及びｐｅｇｓｕｎｅｒｃｅｐｔを基にした新規な医薬組成物 |
| NZ551669A (en) * | 2004-05-31 | 2010-07-30 | Almirall Lab | Combinations comprising antimuscarinic agents and PDE4 inhibitors |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| US20060079544A1 (en) * | 2004-08-13 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic |
| MX2007011273A (es) | 2005-03-16 | 2007-11-08 | Meda Pharma Gmbh & Co Kg | La combinacion de anticolinergicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias. |
| US8012971B2 (en) * | 2005-04-28 | 2011-09-06 | Dainippon Sumitomo Pharma Co., Ltd. | Therapeutic agent for chronic obstructive pulmonary disease |
| DE102005035112A1 (de) * | 2005-07-27 | 2007-02-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neues Verfahren zur Herstellung von Tiotropiumsalzen unter Anwendung von in organischen Lösungsmitteln löslichen N-Methylscopiniumsalzen |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| US7985756B2 (en) | 2005-10-21 | 2011-07-26 | Braincells Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| WO2007071313A2 (en) | 2005-12-21 | 2007-06-28 | Meda Pharma Gmbh & Co Kg | Combination of anticholinergics, glucocorticoids, beta2-ag0nists, pde4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| EP1905440A1 (de) * | 2006-09-06 | 2008-04-02 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EA021019B1 (ru) | 2009-06-18 | 2015-03-31 | Концерт Фармасьютикалс, Инк. | Дейтерированные производные изоиндолин-1,3-диона |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69525978T2 (de) * | 1995-06-06 | 2002-12-19 | Pfizer | Trizyclische 5,6-dihydro-9h-pyrazolo(3,4-c)-1,2,4-triazolo(4,3-alpha)pyridine |
| DE10110772A1 (de) * | 2001-03-07 | 2002-09-12 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren |
-
2002
- 2002-05-23 ES ES02740638T patent/ES2276942T3/es not_active Expired - Lifetime
- 2002-05-23 EP EP02740638A patent/EP1397135B1/en not_active Expired - Lifetime
- 2002-05-23 AT AT02740638T patent/ATE347361T1/de active
- 2002-05-23 JP JP2002592933A patent/JP2004530705A/ja active Pending
- 2002-05-23 AU AU2002314102A patent/AU2002314102A1/en not_active Abandoned
- 2002-05-23 WO PCT/EP2002/005643 patent/WO2002096423A2/en not_active Ceased
- 2002-05-23 CA CA002448363A patent/CA2448363A1/en not_active Abandoned
- 2002-05-23 DE DE60216588T patent/DE60216588T2/de not_active Expired - Lifetime
- 2002-05-23 MX MXPA03010791A patent/MXPA03010791A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03010791A (es) | 2004-03-02 |
| DE60216588T2 (de) | 2007-09-20 |
| WO2002096423A3 (en) | 2003-02-06 |
| ATE347361T1 (de) | 2006-12-15 |
| CA2448363A1 (en) | 2002-12-05 |
| WO2002096423A2 (en) | 2002-12-05 |
| DE60216588D1 (de) | 2007-01-18 |
| AU2002314102A1 (en) | 2002-12-09 |
| EP1397135A2 (en) | 2004-03-17 |
| JP2004530705A (ja) | 2004-10-07 |
| EP1397135B1 (en) | 2006-12-06 |
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