ES2266515T3 - Cepa de lactococcus con autocontencion. - Google Patents
Cepa de lactococcus con autocontencion. Download PDFInfo
- Publication number
- ES2266515T3 ES2266515T3 ES02740565T ES02740565T ES2266515T3 ES 2266515 T3 ES2266515 T3 ES 2266515T3 ES 02740565 T ES02740565 T ES 02740565T ES 02740565 T ES02740565 T ES 02740565T ES 2266515 T3 ES2266515 T3 ES 2266515T3
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- lactococcus
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- C12N9/10—Transferases (2.)
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C12Y—ENZYMES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01201631 | 2001-05-03 | ||
| EP01201631 | 2001-05-03 | ||
| EP01204785 | 2001-12-07 | ||
| EP01204785 | 2001-12-07 |
Publications (1)
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| ES2266515T3 true ES2266515T3 (es) | 2007-03-01 |
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| ES02740565T Expired - Lifetime ES2266515T3 (es) | 2001-05-03 | 2002-05-03 | Cepa de lactococcus con autocontencion. |
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|---|---|
| EP (1) | EP1383897B1 (enExample) |
| JP (2) | JP4347575B2 (enExample) |
| AT (1) | ATE331789T1 (enExample) |
| AU (1) | AU2002314040B2 (enExample) |
| CA (1) | CA2446776C (enExample) |
| DE (1) | DE60212825T2 (enExample) |
| DK (1) | DK1383897T3 (enExample) |
| ES (1) | ES2266515T3 (enExample) |
| WO (1) | WO2002090551A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| EP1513545B1 (en) | 2002-06-19 | 2008-03-19 | Actogenix N.V. | Methods and means to promote gut absorption |
| WO2004056850A2 (en) * | 2002-12-19 | 2004-07-08 | Vib Vzw | Mutant proteins showing increased secretion |
| JP4589618B2 (ja) | 2003-11-28 | 2010-12-01 | 独立行政法人農業生物資源研究所 | 免疫調節性機能を誘導する乳酸菌類とその成分 |
| WO2006018446A2 (en) | 2004-08-20 | 2006-02-23 | Actogenix Nv | Method to improve lactococcus preservation |
| ES2405552T3 (es) | 2005-11-29 | 2013-05-31 | Actogenix N.V. | Inducción de tolerancia mucosa a antiantígenos de células beta de islotes pancreáticos |
| CA2672229A1 (en) * | 2006-12-14 | 2008-06-19 | Actogenix N.V. | Delivery of binding molecules to induce immunomodulation |
| EP3124614B1 (en) | 2007-01-12 | 2022-06-08 | Intrexon Actobiotics NV | Lactococcus promoters and uses thereof |
| EP2774621B1 (en) | 2007-01-25 | 2018-01-24 | Intrexon Actobiotics NV | Treatment of immune disease by mucosal delivery of antigens |
| EP2344626B1 (en) * | 2008-09-29 | 2017-03-29 | Intrexon Actobiotics NV | Reduced colonization of microbes at the mucosa |
| US9920324B2 (en) | 2011-06-01 | 2018-03-20 | Intrexon Actobiotics Nv | Polycistronic expression system for bacteria |
| EP2758512B1 (en) | 2011-09-23 | 2018-05-09 | Intrexon Actobiotics NV | Modified gram positive bacteria and uses thereof |
| BR112014006883A8 (pt) | 2011-09-23 | 2018-06-26 | Actogenix Nv | bactéria gram-positiva não patogênica carecendo de atividade do componente llc do sistema pts celobiose específico (ptcc), medicamento, aditivo alimentar, composição probiótica, ou cultura iniciadora, produto alimentar e métodos |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| JP7095993B2 (ja) * | 2015-03-02 | 2022-07-05 | シンロジック オペレーティング カンパニー インコーポレイテッド | 消化管炎症低下および／または消化管粘膜バリア強化の利益を享受する疾患処置のために操作された細菌 |
| CN106148254B (zh) * | 2015-03-26 | 2019-11-12 | 南京华贞生物医药科技有限公司 | 一种用于减肥降脂的转化体及其构建方法与应用 |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| EP3377518B1 (en) | 2015-11-16 | 2022-04-13 | Synlogic Operating Company, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| EP3402499B1 (en) | 2016-01-14 | 2021-07-21 | Intrexon Actobiotics NV | Compositions and methods for the treatment of type 1 diabetes |
| CN109843320A (zh) | 2016-09-02 | 2019-06-04 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 稳定表达il-10和胰岛素的遗传修饰的细菌 |
| RU2762940C2 (ru) | 2016-09-13 | 2021-12-24 | Интрексон Актобиотикс Н.В. | Мукоадгезивный микроорганизм |
| WO2020075171A1 (en) | 2018-10-11 | 2020-04-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Bacteria expressing single chain antibodies against toll-like receptors |
| CN114761028A (zh) | 2019-09-27 | 2022-07-15 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 乳糜泻的治疗 |
| BR112022018571A2 (pt) | 2020-03-20 | 2022-11-01 | Synlogic Operating Co Inc | Microrganismos manipulados para reduzir a hiperfenilalaninemia |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4231764A1 (de) * | 1992-09-23 | 1994-03-24 | Inst Pflanzengenetik & Kultur | Verfahren zur chromosomalen Integration eines Produkt-Gens |
-
2002
- 2002-05-03 JP JP2002587611A patent/JP4347575B2/ja not_active Expired - Fee Related
- 2002-05-03 CA CA2446776A patent/CA2446776C/en not_active Expired - Fee Related
- 2002-05-03 EP EP02740565A patent/EP1383897B1/en not_active Expired - Lifetime
- 2002-05-03 DE DE60212825T patent/DE60212825T2/de not_active Expired - Lifetime
- 2002-05-03 DK DK02740565T patent/DK1383897T3/da active
- 2002-05-03 ES ES02740565T patent/ES2266515T3/es not_active Expired - Lifetime
- 2002-05-03 WO PCT/EP2002/004942 patent/WO2002090551A2/en not_active Ceased
- 2002-05-03 AT AT02740565T patent/ATE331789T1/de active
- 2002-05-03 AU AU2002314040A patent/AU2002314040B2/en not_active Ceased
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2008
- 2008-10-07 JP JP2008260591A patent/JP2009060913A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002090551A3 (en) | 2003-03-27 |
| JP2004533246A (ja) | 2004-11-04 |
| EP1383897A2 (en) | 2004-01-28 |
| EP1383897B1 (en) | 2006-06-28 |
| DE60212825D1 (de) | 2006-08-10 |
| JP4347575B2 (ja) | 2009-10-21 |
| WO2002090551A2 (en) | 2002-11-14 |
| DE60212825T2 (de) | 2007-01-11 |
| DK1383897T3 (da) | 2006-10-30 |
| AU2002314040B2 (en) | 2007-06-28 |
| CA2446776C (en) | 2011-07-12 |
| JP2009060913A (ja) | 2009-03-26 |
| CA2446776A1 (en) | 2002-11-14 |
| ATE331789T1 (de) | 2006-07-15 |
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