ES2192561T3 - Adn que codifica el receptor ip de prostaglandina. - Google Patents

Adn que codifica el receptor ip de prostaglandina.

Info

Publication number
ES2192561T3
ES2192561T3 ES94928741T ES94928741T ES2192561T3 ES 2192561 T3 ES2192561 T3 ES 2192561T3 ES 94928741 T ES94928741 T ES 94928741T ES 94928741 T ES94928741 T ES 94928741T ES 2192561 T3 ES2192561 T3 ES 2192561T3
Authority
ES
Spain
Prior art keywords
prostaglandine
receiver
receptor
dna coding
host cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94928741T
Other languages
English (en)
Inventor
Mark Abramovitz
Yves Boie
Richard Grygorczyk
Kathleen Metters
Thomas H Rushmore
Deborah M Slipetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22461361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2192561(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Application granted granted Critical
Publication of ES2192561T3 publication Critical patent/ES2192561T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE HA IDENTIFICADO UN NUEVO RECEPTOR DE LA PROSTAGLANDINA Y EL ADN QUE CODIFICA EL RECEPTOR HA SIDO AISLADO, PURIFICADO, SECUENCIADO Y EXPRESADO EN CELULAS ANFITRIONAS. ESTE ADN QUE CODIFICA EL NUEVO RECEPTOR DE LA PROSTAGLANDINA Y LAS CELULAS ANFITRIONAS QUE EXPRESAN EL RECEPTOR SON UTILIZADOS PARA IDENTIFICAR MODULADORES DEL RECEPTOR DE LA PROSTAGLANDINA.
ES94928741T 1993-10-06 1994-10-03 Adn que codifica el receptor ip de prostaglandina. Expired - Lifetime ES2192561T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/134,012 US5516652A (en) 1993-10-06 1993-10-06 DNA encoding prostaglandin receptor IP

Publications (1)

Publication Number Publication Date
ES2192561T3 true ES2192561T3 (es) 2003-10-16

Family

ID=22461361

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94928741T Expired - Lifetime ES2192561T3 (es) 1993-10-06 1994-10-03 Adn que codifica el receptor ip de prostaglandina.

Country Status (8)

Country Link
US (3) US5516652A (es)
EP (1) EP0722462B1 (es)
JP (1) JP3029125B2 (es)
AT (1) ATE236932T1 (es)
CA (1) CA2173595C (es)
DE (1) DE69432470T2 (es)
ES (1) ES2192561T3 (es)
WO (1) WO1995009872A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021863A1 (fr) * 1994-02-10 1995-08-17 Ono Pharmaceutical Co., Ltd. Recepteur de la prostaglandine i¿2?
US6395878B1 (en) * 1994-05-05 2002-05-28 Allergan Sales, Inc. Nucleic acid encoding a human EP prostaglandin receptor
JP3064015B2 (ja) 1995-01-26 2000-07-12 メルク フロスト カナダ アンド カンパニー プロスタグランジンレセプターdp
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ C16不飽和fp−選択的プロスタグランジン類縁体
US6894175B1 (en) * 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US6673760B1 (en) * 2000-06-29 2004-01-06 Ecolab Inc. Rinse agent composition and method for rinsing a substrate surface
WO2003062393A2 (en) * 2002-01-22 2003-07-31 Bristol-Myers Squibb Company G protein-coupled receptor variants
DE10229872A1 (de) * 2002-07-03 2004-01-29 Curevac Gmbh Immunstimulation durch chemisch modifizierte RNA
US20060171945A1 (en) * 2003-02-14 2006-08-03 Critchley Hilary Octavia D Ip receptor antagonists for the treatment of pathological uterine conditions
DE102006035618A1 (de) * 2006-07-31 2008-02-07 Curevac Gmbh Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
AU2007280690C1 (en) 2006-07-31 2012-08-23 Curevac Gmbh Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
WO2009030254A1 (en) 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
KR101483715B1 (ko) 2008-01-31 2015-01-19 큐어백 게엠바하 면역증강제/애주번트인 화학식(NuGlXmGnNv)a를 포함하는 핵산 및 이의 유도체
WO2010037408A1 (en) 2008-09-30 2010-04-08 Curevac Gmbh Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20110053829A1 (en) 2009-09-03 2011-03-03 Curevac Gmbh Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
WO2011159904A1 (en) * 2010-06-17 2011-12-22 The Trustees Of The University Of Pennsylvania Methods for predicting cellular signaling responses to combinatorial stimuli
US8754085B2 (en) 2010-07-14 2014-06-17 Novartis Ag Pyrido[2,3-b]pyrazine compounds useful as IP receptor agonist
EP2955230A1 (en) 2010-07-30 2015-12-16 CureVac AG Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
CN104053659B (zh) 2012-01-13 2016-11-09 诺华股份有限公司 用于治疗肺动脉高压(pah)及相关病症的作为ip 受体激动剂的稠合的吡咯类
WO2013113326A1 (en) 2012-01-31 2013-08-08 Curevac Gmbh Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
JP2016507582A (ja) 2013-02-13 2016-03-10 ノバルティス アーゲー Ip受容体アゴニスト複素環式化合物
AU2014310934B2 (en) 2013-08-21 2019-09-12 CureVac SE Respiratory syncytial virus (RSV) vaccine
WO2015149944A2 (en) 2014-04-01 2015-10-08 Curevac Gmbh Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant

Also Published As

Publication number Publication date
CA2173595A1 (en) 1995-04-13
EP0722462A1 (en) 1996-07-24
JPH09503213A (ja) 1997-03-31
US5728808A (en) 1998-03-17
EP0722462B1 (en) 2003-04-09
US5516652A (en) 1996-05-14
DE69432470T2 (de) 2004-01-29
JP3029125B2 (ja) 2000-04-04
ATE236932T1 (de) 2003-04-15
DE69432470D1 (de) 2003-05-15
CA2173595C (en) 2001-06-12
US6365360B1 (en) 2002-04-02
WO1995009872A1 (en) 1995-04-13

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