ES2187947T3 - Procedimiento para la determinacion simultanea de antigenos de hiv y anticuerpos de hiv. - Google Patents
Procedimiento para la determinacion simultanea de antigenos de hiv y anticuerpos de hiv.Info
- Publication number
- ES2187947T3 ES2187947T3 ES98912441T ES98912441T ES2187947T3 ES 2187947 T3 ES2187947 T3 ES 2187947T3 ES 98912441 T ES98912441 T ES 98912441T ES 98912441 T ES98912441 T ES 98912441T ES 2187947 T3 ES2187947 T3 ES 2187947T3
- Authority
- ES
- Spain
- Prior art keywords
- hiv1
- hiv
- procedure
- sub0
- hiv2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 abstract 3
- 241000713340 Human immunodeficiency virus 2 Species 0.000 abstract 3
- 101710205625 Capsid protein p24 Proteins 0.000 abstract 2
- 101710177166 Phosphoprotein Proteins 0.000 abstract 2
- 101710149279 Small delta antigen Proteins 0.000 abstract 2
- 102100031987 Transmembrane emp24 domain-containing protein 2 Human genes 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 101710072850 Poxin Proteins 0.000 abstract 1
- 101710142282 Protein P26 Proteins 0.000 abstract 1
- 102100032106 Transmembrane emp24 domain-containing protein 3 Human genes 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000011895 specific detection Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
Abstract
La invención se refiere a un procedimiento para la diagnosis de una infección por HIV por medio de un inmunoensayo que detecta específicamente el antígeno p24 del antígeno HIV, HIV1-subO y/o el antígeno p26 del antígeno HIV2, al menos un anticuerpo contra la zona env del HIV1, HIV1-subO y/o HIV2 y al menos un anticuerpo contra la zona pol y/o gag del HIV1, HIV1-subO y/o HIV2. La invención se refiere además a equipos de reactivos y a tiras de prueba adecuadas para el procedimiento de diagnosis y a los anticuerpos monoclonales contra p24 y la utilización de los mismos.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19709762 | 1997-03-10 | ||
DE19709762 | 1997-03-10 | ||
DE19727943 | 1997-07-01 | ||
DE19727943A DE19727943A1 (de) | 1997-03-10 | 1997-07-01 | Verfahren zur simultanen Bestimmung von HIV-Antigenen und HIV-Antikörpern |
PCT/EP1998/001235 WO1998040744A1 (de) | 1997-03-10 | 1998-03-05 | Verfahren zur simultanen bestimmung von hiv-antigenen und hiv-antikörpern |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2187947T3 true ES2187947T3 (es) | 2003-06-16 |
ES2187947T5 ES2187947T5 (es) | 2014-01-29 |
Family
ID=26034683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98912441.7T Expired - Lifetime ES2187947T5 (es) | 1997-03-10 | 1998-03-05 | Procedimiento para la detección simultánea de antígenos de HIV y anticuerpos de HIV |
Country Status (8)
Country | Link |
---|---|
US (1) | US6593079B1 (es) |
EP (1) | EP0972198B2 (es) |
JP (1) | JP3534417B2 (es) |
AT (1) | ATE228248T1 (es) |
AU (1) | AU6727798A (es) |
CA (1) | CA2283058C (es) |
ES (1) | ES2187947T5 (es) |
WO (1) | WO1998040744A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO311807B1 (no) * | 1999-03-04 | 2002-01-28 | Bionor Immuno As | HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV |
AU2004200155C1 (en) * | 1999-03-04 | 2015-07-23 | Bionor Immuno As | HIV peptides, antigens, vaccine compositions, immunoassay kit and a method of detecting antibodies induced by HIV |
DE10059720A1 (de) | 2000-11-30 | 2002-06-06 | Roche Diagnostics Gmbh | Verwendung intramolekular kovalent vernetzter Proteine als Bindepartner in Immunoassays |
US6818392B2 (en) * | 2000-12-06 | 2004-11-16 | Abbott Laboratories | Monoclonal antibodies to human immunodeficiency virus and uses thereof |
FR2839555B1 (fr) | 2002-05-10 | 2007-07-27 | Bio Rad Pasteur | Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux |
FR2882557A1 (fr) * | 2005-02-25 | 2006-09-01 | Centre Nat Rech Scient | Epitopes de vih et composition pharmaceutique les contenant |
US8324153B2 (en) | 2008-05-06 | 2012-12-04 | New York Blood Center, Inc. | Antiviral cell-penetrating peptides |
US8937154B2 (en) | 2006-10-05 | 2015-01-20 | New York Blood Center, Inc. | Stabilized therapeutic small helical antiviral peptides |
EP1933145B1 (en) * | 2006-12-11 | 2011-09-28 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
US20100297607A1 (en) | 2009-05-20 | 2010-11-25 | Jian Zheng | Reagents For HCV Antigen-Antibody Combination Assays |
EP2550362B1 (en) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
PT2691530T (pt) | 2011-06-10 | 2018-05-10 | Univ Oregon Health & Science | Glicoproteínas e vectores recombinantes cmv |
US20130189754A1 (en) | 2011-09-12 | 2013-07-25 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3445816C1 (de) | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flaechenfoermiges diagnostisches Mittel |
DE3636540A1 (de) | 1986-10-27 | 1988-04-28 | Behringwerke Ag | Verfahren zur bestimmung von anti-hiv, mittel dazu und ihre verwendung in diesem verfahren |
DE3705686C2 (de) | 1987-02-23 | 1995-11-30 | Boehringer Mannheim Gmbh | Verfahren zur Bestimmung von Antikörpern |
EP1369427A3 (en) † | 1988-06-09 | 2004-05-12 | Innogenetics N.V. | HIV-3 retrovirus strains and their use |
EP0386713B1 (en) | 1989-03-09 | 1996-09-18 | Abbott Laboratories | Immunoassay for antibodies to HIV |
JP2001504572A (ja) * | 1992-04-09 | 2001-04-03 | アボツト・ラボラトリーズ | Hiv抗原及びhiv抗体を検出するためのアッセイ |
DE4236189A1 (de) | 1992-10-27 | 1994-04-28 | Boehringer Mannheim Gmbh | Verfahren zur simultanen Bestimmung von Antigenen und Antikörpern |
JP3604147B2 (ja) | 1994-07-25 | 2004-12-22 | ロシュ ダイアグノスティックス ゲーエムベーハー | 金属キレート標識ペプチド |
AU684992B2 (en) | 1994-07-25 | 1998-01-08 | Boehringer Mannheim Gmbh | Hapten-marked peptides |
CN1148578C (zh) | 1994-07-25 | 2004-05-05 | 罗切诊断学有限公司 | 免疫测定特异抗体的方法、所用试剂、抗原及其用途 |
-
1998
- 1998-03-05 WO PCT/EP1998/001235 patent/WO1998040744A1/de active IP Right Grant
- 1998-03-05 AT AT98912441T patent/ATE228248T1/de active
- 1998-03-05 ES ES98912441.7T patent/ES2187947T5/es not_active Expired - Lifetime
- 1998-03-05 EP EP98912441.7A patent/EP0972198B2/de not_active Expired - Lifetime
- 1998-03-05 CA CA2283058A patent/CA2283058C/en not_active Expired - Lifetime
- 1998-03-05 AU AU67277/98A patent/AU6727798A/en not_active Abandoned
- 1998-03-05 US US09/381,009 patent/US6593079B1/en not_active Expired - Lifetime
- 1998-03-05 JP JP53917798A patent/JP3534417B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1998040744A1 (de) | 1998-09-17 |
EP0972198A1 (de) | 2000-01-19 |
ES2187947T5 (es) | 2014-01-29 |
AU6727798A (en) | 1998-09-29 |
ATE228248T1 (de) | 2002-12-15 |
EP0972198B1 (de) | 2002-11-20 |
CA2283058A1 (en) | 1998-09-17 |
CA2283058C (en) | 2011-09-27 |
JP3534417B2 (ja) | 2004-06-07 |
JP2001514749A (ja) | 2001-09-11 |
US6593079B1 (en) | 2003-07-15 |
EP0972198B2 (de) | 2013-12-11 |
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