ES2187180T3 - Genes que confieren un fenotipo obeso. - Google Patents

Genes que confieren un fenotipo obeso.

Info

Publication number
ES2187180T3
ES2187180T3 ES99939531T ES99939531T ES2187180T3 ES 2187180 T3 ES2187180 T3 ES 2187180T3 ES 99939531 T ES99939531 T ES 99939531T ES 99939531 T ES99939531 T ES 99939531T ES 2187180 T3 ES2187180 T3 ES 2187180T3
Authority
ES
Spain
Prior art keywords
obeso
phenotype
conference
genes
est
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99939531T
Other languages
English (en)
Inventor
Iain Robinson
Jonathan Paul Stoye
David Flavell
Sara Elizabeth Wells
Tissier Paul Le
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9817566.4A external-priority patent/GB9817566D0/en
Priority claimed from GBGB9910522.3A external-priority patent/GB9910522D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Application granted granted Critical
Publication of ES2187180T3 publication Critical patent/ES2187180T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lubricants (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invención describe un gen desconocido previamente, denominado 5''OT-EST, que es responsable de inducir una obesidad y/o fenotipos de infertilidad en animales transgénicos, y animales transgénicos que tienen mutantes del 5''OT-EST que son útiles para analizar compuestos para el tratamiento de la obesidad y la infertilidad.
ES99939531T 1998-08-12 1999-08-12 Genes que confieren un fenotipo obeso. Expired - Lifetime ES2187180T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9817566.4A GB9817566D0 (en) 1998-08-12 1998-08-12 Gene
GBGB9910522.3A GB9910522D0 (en) 1999-05-06 1999-05-06 Gene

Publications (1)

Publication Number Publication Date
ES2187180T3 true ES2187180T3 (es) 2003-05-16

Family

ID=26314200

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99939531T Expired - Lifetime ES2187180T3 (es) 1998-08-12 1999-08-12 Genes que confieren un fenotipo obeso.

Country Status (11)

Country Link
US (2) US6998472B1 (es)
EP (1) EP0996727B1 (es)
JP (1) JP2002522073A (es)
AT (1) ATE230796T1 (es)
AU (1) AU770653B2 (es)
CA (1) CA2339518A1 (es)
DE (1) DE69904794T2 (es)
DK (1) DK0996727T3 (es)
ES (1) ES2187180T3 (es)
GB (1) GB2344107B (es)
WO (1) WO2000009686A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020129396A1 (en) * 2000-07-06 2002-09-12 Allen Keith D. Transgenic mice containing CX2 gene disruptions
AU2001293164A1 (en) * 2000-09-29 2002-04-08 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Detection of fecal contamination
US7118870B2 (en) 2001-09-28 2006-10-10 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Detection of fecal contamination using nucleic acid molecules that recognize bacterial 16S rDNA sequences
JP2006094701A (ja) * 2002-09-17 2006-04-13 Chugai Pharmaceut Co Ltd ７ｆ４遺伝子トランスジェニック動物
GB0301230D0 (en) * 2003-01-20 2003-02-19 Medical Res Council Model
RU2764307C1 (ru) * 2020-12-29 2022-01-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ижевская государственная сельскохозяйственная академия" Способ определения комплексного индекса телосложения и экстерьерно-конституционального типа животных

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843652A (en) * 1993-05-21 1998-12-01 Lockheed Martin Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
EP0844253A1 (en) * 1996-11-25 1998-05-27 Smithkline Beecham Plc Polynucleotides and polypeptides related to the "Tubby" family
WO1999004265A2 (en) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Cancer associated nucleic acids and polypeptides

Also Published As

Publication number Publication date
US6998472B1 (en) 2006-02-14
GB2344107A (en) 2000-05-31
CA2339518A1 (en) 2000-02-24
DK0996727T3 (da) 2003-04-28
JP2002522073A (ja) 2002-07-23
AU770653B2 (en) 2004-02-26
DE69904794D1 (de) 2003-02-13
DE69904794T2 (de) 2003-10-23
EP0996727A1 (en) 2000-05-03
GB0000654D0 (en) 2000-03-01
US20060064765A1 (en) 2006-03-23
ATE230796T1 (de) 2003-01-15
GB2344107B (en) 2000-12-06
AU5380199A (en) 2000-03-06
WO2000009686A1 (en) 2000-02-24
EP0996727B1 (en) 2003-01-08

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