ES2183714A1 - Fabrication of oxalate based oncology treatment agent useful in chemical industry, comprising mixing cyclohexanodiamine and tetraiodoplatinite solutions with silver nitrate and potassium oxalate - Google Patents
Fabrication of oxalate based oncology treatment agent useful in chemical industry, comprising mixing cyclohexanodiamine and tetraiodoplatinite solutions with silver nitrate and potassium oxalateInfo
- Publication number
- ES2183714A1 ES2183714A1 ES200101213A ES200101213A ES2183714A1 ES 2183714 A1 ES2183714 A1 ES 2183714A1 ES 200101213 A ES200101213 A ES 200101213A ES 200101213 A ES200101213 A ES 200101213A ES 2183714 A1 ES2183714 A1 ES 2183714A1
- Authority
- ES
- Spain
- Prior art keywords
- oxalate
- cyclohexanodiamine
- tetraiodoplatinite
- mixing
- chemical industry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
An oxalate-based oncology treatment agent, useful in the chemical industry, is fabricated by mixing (1R,2R)-cyclohexanodiamine based aqueous solution with potassium tetraiodoplatinite (I4PtK2) aqueous solution. The resulting (1R,2R-cyclohexanodiamine)-platinum (II), after silver nitrate solution treatment, receives excess of potassium oxalate aqueous solution. The crystalline product is (1R,2R)-cyclohexanodiamine)-platinum (II) oxalate.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101213A ES2183714B1 (en) | 2001-05-25 | 2001-05-25 | A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II). |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101213A ES2183714B1 (en) | 2001-05-25 | 2001-05-25 | A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II). |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2183714A1 true ES2183714A1 (en) | 2003-03-16 |
ES2183714B1 ES2183714B1 (en) | 2004-01-16 |
Family
ID=8497855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200101213A Expired - Fee Related ES2183714B1 (en) | 2001-05-25 | 2001-05-25 | A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II). |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2183714B1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010081924A1 (en) * | 2009-01-13 | 2010-07-22 | Capital, Business Y Gestión De Finanzas, S.L. | Process for preparing pharmaceutical-grade neutral platinum (ii) antineoplastic derivatives having low silver content |
WO2010149337A1 (en) | 2009-06-26 | 2010-12-29 | Umicore Ag & Co. Kg | Process for preparation of 1,2-diamino-cyclohexane-platinum (ii) complexes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0617043A1 (en) * | 1992-01-13 | 1994-09-28 | Tanaka Kikinzoku Kogyo K.K. | Platinum compound and process of preparing same |
EP0625523A1 (en) * | 1993-05-21 | 1994-11-23 | Tanaka Kikinzoku Kogyo K.K. | Cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same |
ES2125320T3 (en) * | 1992-04-22 | 1999-03-01 | Tanaka Precious Metal Ind | CIS-OXALATE (TRANS-L-1,2-CYCLOHEXANDIAMINE) PT (II) OPTICALLY PURE AND PROCEDURE FOR SOLVING OPTICAL ISOMERS OF A PLATINUM COMPLEX COMPOSITE. |
-
2001
- 2001-05-25 ES ES200101213A patent/ES2183714B1/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0617043A1 (en) * | 1992-01-13 | 1994-09-28 | Tanaka Kikinzoku Kogyo K.K. | Platinum compound and process of preparing same |
ES2125320T3 (en) * | 1992-04-22 | 1999-03-01 | Tanaka Precious Metal Ind | CIS-OXALATE (TRANS-L-1,2-CYCLOHEXANDIAMINE) PT (II) OPTICALLY PURE AND PROCEDURE FOR SOLVING OPTICAL ISOMERS OF A PLATINUM COMPLEX COMPOSITE. |
EP0625523A1 (en) * | 1993-05-21 | 1994-11-23 | Tanaka Kikinzoku Kogyo K.K. | Cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010081924A1 (en) * | 2009-01-13 | 2010-07-22 | Capital, Business Y Gestión De Finanzas, S.L. | Process for preparing pharmaceutical-grade neutral platinum (ii) antineoplastic derivatives having low silver content |
WO2010149337A1 (en) | 2009-06-26 | 2010-12-29 | Umicore Ag & Co. Kg | Process for preparation of 1,2-diamino-cyclohexane-platinum (ii) complexes |
US8637692B2 (en) | 2009-06-26 | 2014-01-28 | Umicore Ag & Co. Kg | Process for preparation of 1,2-diamino-cyclohexane-platinum (II) complexes |
Also Published As
Publication number | Publication date |
---|---|
ES2183714B1 (en) | 2004-01-16 |
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