ES2181444T3 - Composicion para la induccion de una respuesta inmunologica especifica de un tumor, metodo para la produccion y utilizacion de dicha composicion en el tratamiento de neoplasias. - Google Patents

Composicion para la induccion de una respuesta inmunologica especifica de un tumor, metodo para la produccion y utilizacion de dicha composicion en el tratamiento de neoplasias.

Info

Publication number
ES2181444T3
ES2181444T3 ES99924991T ES99924991T ES2181444T3 ES 2181444 T3 ES2181444 T3 ES 2181444T3 ES 99924991 T ES99924991 T ES 99924991T ES 99924991 T ES99924991 T ES 99924991T ES 2181444 T3 ES2181444 T3 ES 2181444T3
Authority
ES
Spain
Prior art keywords
composition
tumor
production
neoplasias
induction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99924991T
Other languages
English (en)
Inventor
Tim Rohnisch
Katharina Pachmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
APALEXO BIOTECHNOLOGIE GmbH
Original Assignee
APALEXO BIOTECHNOLOGIE GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APALEXO BIOTECHNOLOGIE GmbH filed Critical APALEXO BIOTECHNOLOGIE GmbH
Application granted granted Critical
Publication of ES2181444T3 publication Critical patent/ES2181444T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Vacuna, que comprende un bacteriófago o un fragmento funcional equivalente del mismo, el cual expresa por lo menos, un antígeno específico de un tumor y/o un antígeno asociado a un tumor, con una longitud por lo menos de 20 aminoácidos, como proteína de fusión con una proteína de la envoltura del fago cpVIII ó un fragmento o un derivado funcional equivalente del mismo, sobre su superficie, y eventualmente contiene un soporte farmacéuticamente aceptable y/o un diluyente farmacéuticamente aceptable.
ES99924991T 1998-05-15 1999-05-17 Composicion para la induccion de una respuesta inmunologica especifica de un tumor, metodo para la produccion y utilizacion de dicha composicion en el tratamiento de neoplasias. Expired - Lifetime ES2181444T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19821925A DE19821925A1 (de) 1998-05-15 1998-05-15 Verfahren zur Herstellung einer Zusammensetzung zur Induktion einer tumorspezifischen Immunantwort, sowie Verwendung der Zusammensetzung zur Behandlung von Neoplasien
EP9903353 1999-05-14

Publications (1)

Publication Number Publication Date
ES2181444T3 true ES2181444T3 (es) 2003-02-16

Family

ID=7867943

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99924991T Expired - Lifetime ES2181444T3 (es) 1998-05-15 1999-05-17 Composicion para la induccion de una respuesta inmunologica especifica de un tumor, metodo para la produccion y utilizacion de dicha composicion en el tratamiento de neoplasias.

Country Status (9)

Country Link
EP (2) EP1214942A3 (es)
AT (1) ATE222772T1 (es)
AU (1) AU764390B2 (es)
CA (1) CA2328057A1 (es)
DE (2) DE19821925A1 (es)
DK (1) DK1077720T3 (es)
ES (1) ES2181444T3 (es)
IL (1) IL139683A0 (es)
WO (1) WO1999059624A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003293958A1 (en) * 2002-12-23 2004-07-22 Apalexo Biotechnologie Gmbh Purification of recombinant filamental bacteriophages by means of affinity chromatography to increase the immunogenicity and efficacy of phagic vaccines
CN114907472A (zh) * 2022-04-07 2022-08-16 武汉爱博泰克生物科技有限公司 一种精准复制抗体的方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262177A (en) * 1986-02-07 1993-11-16 Oncogen Recombinant viruses encoding the human melanoma-associated antigen
NZ219192A (en) * 1986-02-07 1991-10-25 Oncogen Peptides related to p97 melanoma-associated peptide, recombinant virus and vaccines
GB9022190D0 (en) * 1990-10-12 1990-11-28 Perham Richard N Immunogenic material
US5674486A (en) * 1991-06-25 1997-10-07 San Diego Regional Cancer Center Cancer immunotherapy with carrier cells
US5759535A (en) * 1994-05-13 1998-06-02 Research Corporation Technologies, Inc. Immunotherapeutic strategies for the treatment of cancer

Also Published As

Publication number Publication date
ATE222772T1 (de) 2002-09-15
WO1999059624A3 (de) 2000-01-27
DE19821925A1 (de) 1999-11-18
AU764390B2 (en) 2003-08-14
EP1077720A2 (de) 2001-02-28
IL139683A0 (en) 2002-02-10
DE59902472D1 (de) 2002-10-02
EP1077720B1 (de) 2002-08-28
DK1077720T3 (da) 2004-03-22
EP1214942A3 (de) 2002-10-02
CA2328057A1 (en) 1999-11-25
EP1214942A2 (de) 2002-06-19
WO1999059624A2 (de) 1999-11-25
AU4144299A (en) 1999-12-06

Similar Documents

Publication Publication Date Title
ATE328095T1 (de) Verbesserungen des stärkegehaltes von pflanzen
NO20013701D0 (no) HER-2/neu-fusjonsproteiner
ATE293690T1 (de) Verwendung vom krebs-assoziierten antigen 5t4 zur immuntherapie
EP0681585A4 (en) FACTORS ASSOCIATED TO TATA-BINDING PROTEINS, NUCLEIC ACIDS ENCODING TAFS AND METHODS FOR USE THEREOF.
EP1214098A4 (en) CAPSIDE-MODIFIED RECOMBINANT ADENOVIRUS AND METHOD FOR USE THEREOF
WO1999025878A3 (en) Methods for modulating and identifying cellular senescence
HK1049185A1 (zh) 可改螢光蛋白
DK1082423T3 (da) Cyclin E2-gener og -proteiner
ATE309356T1 (de) Konstruierte fluoreszenzproteine mit langen wellenlängen
ES2181444T3 (es) Composicion para la induccion de una respuesta inmunologica especifica de un tumor, metodo para la produccion y utilizacion de dicha composicion en el tratamiento de neoplasias.
DE59712554D1 (de) Rekombinante expression von s-layer-proteinen
HUP9901786A2 (hu) Eljárás helypreferált rákos áttétképződéssel kapcsolatos gének azonosítására immuno-mágneses sejtszeparáció felhasználásával
DE3882455D1 (de) Verfahren zur herstellung von proteinen in loeslicher form.
EP0888374A4 (en) NUCLEIC ACID LIGANDS WITH HIGH AFFINITY FOR THE PROTEINS OF THE COMPLEMENT SYSTEM
PT870015E (pt) Novas xilanases os genes que as codificam e as suas utilizacoes
FR2709132B1 (fr) Fragment d'ADN portant le gène codant pour l'enzyme de fragmentation du N-acétylhéparosane et les séquences adjacentes permettant son expression, enzyme recombinée et son utilisation.
WO2000053785A3 (en) Method to improve translation of polypeptides by using untranslated regions from heat-shock proteins
IT8521507A0 (it) Vettore di clonaggio, molecole di dna ricombinante, ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni.
ATE327334T1 (de) Atp- und nukleinsäure-bindendes protein mit helikase- und atpase eigenschaften
DE60134956D1 (de) Gene differentiell experimiert in brudtkrebs
WO2002006340A3 (en) Tetraspan protein and uses thereof
DK1214453T3 (da) Hidtil ukendte cellecykluskontrolpunktgener og proteiner kodet deraf
CA2347371A1 (en) HEMATOPOIETIC REGULATION FACTORS AND METHODS OF USE
BR9810643A (pt) Genes e proteìnas de telomerase de vertebrado, eutilização dos mesmos
WO2006073587A3 (en) Hemipteran 5-hydroxytryptamine 7 serotonin receptor