ES2177401B1 - Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano. - Google Patents

Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano.

Info

Publication number
ES2177401B1
ES2177401B1 ES200001604A ES200001604A ES2177401B1 ES 2177401 B1 ES2177401 B1 ES 2177401B1 ES 200001604 A ES200001604 A ES 200001604A ES 200001604 A ES200001604 A ES 200001604A ES 2177401 B1 ES2177401 B1 ES 2177401B1
Authority
ES
Spain
Prior art keywords
esterification
sterols
propane
tocopherols
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200001604A
Other languages
English (en)
Other versions
ES2177401A1 (es
Inventor
Andres Eloy Muro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitae Caps S A
VITAE-CAPS SA
Original Assignee
Vitae Caps S A
VITAE-CAPS SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitae Caps S A, VITAE-CAPS SA filed Critical Vitae Caps S A
Priority to ES200001604A priority Critical patent/ES2177401B1/es
Priority to EP00940429A priority patent/EP1426368A1/en
Priority to PCT/ES2000/000237 priority patent/WO2002000640A1/es
Publication of ES2177401A1 publication Critical patent/ES2177401A1/es
Application granted granted Critical
Publication of ES2177401B1 publication Critical patent/ES2177401B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Pyrane Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Procedimiento de extracción y purificación de tocoferoles naturales y esteroles por esterificación con trimetilol propano, que consiste en una esterificación especialmente catalizada con el fin de conseguir convertir los ácidos grasos presentes en el destilado de desodorización en esteres de alto peso molecular de poca volatilidad y que por tanto en una destilación selectiva permanezcan en el residuo de la misma, efectuándose la esterificación de ácidos grasos utilizando como alcohol trimetil- ol-propano, y como catalizador ácido hipofosforoso, así como en la dilución se emplea metanol en la proporción de 1 a 7 y el centrifugado o filtrado a -30°C, realizándose la destilación molecular para separar ésteres de ácidos grasos y trimetil-ol- propano, de tocoferoles, esteroles e hidrocarburos, realizándose la destilación molecular para purificar los tocoferoles.
ES200001604A 2000-06-28 2000-06-28 Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano. Expired - Fee Related ES2177401B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES200001604A ES2177401B1 (es) 2000-06-28 2000-06-28 Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano.
EP00940429A EP1426368A1 (en) 2000-06-28 2000-07-05 Method for extracting and purifying natural tocopherols and sterols by esterification with trimethyl propane
PCT/ES2000/000237 WO2002000640A1 (es) 2000-06-28 2000-07-05 Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200001604A ES2177401B1 (es) 2000-06-28 2000-06-28 Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano.

Publications (2)

Publication Number Publication Date
ES2177401A1 ES2177401A1 (es) 2002-12-01
ES2177401B1 true ES2177401B1 (es) 2004-09-16

Family

ID=8494047

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200001604A Expired - Fee Related ES2177401B1 (es) 2000-06-28 2000-06-28 Procedimiento de extraccion y purificacion de tocoferoles naturales y esteroles por esterificacion con trimetilol propano.

Country Status (3)

Country Link
EP (1) EP1426368A1 (es)
ES (1) ES2177401B1 (es)
WO (1) WO2002000640A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102234228A (zh) * 2010-05-05 2011-11-09 北京石油化工学院 离子液体催化合成三羟甲基丙烷脂肪酸酯的方法
CN103319446B (zh) * 2013-07-05 2015-07-29 河南懿丰油脂有限公司 从植物油脱臭馏出物中提取天然维生素e的方法
MY193786A (en) * 2015-01-12 2022-10-27 Ho Sue San David Recovery of tocopherols/tocotrienols, carotenoids, glycerols, sterols and fatty acid esters from crude vegetable oil and the process thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5487817A (en) * 1993-02-11 1996-01-30 Hoffmann-La Roche Inc. Process for tocopherols and sterols from natural sources
ES2093570B1 (es) * 1995-06-15 1997-07-01 Saura Lopez Domingo Procedimiento para la preparacion enzimatica de extractos oleosos enriquecidos en antioxidantes naturales.
US5703252A (en) * 1995-12-13 1997-12-30 Henkel Corporation Recovery of Tocopherols

Also Published As

Publication number Publication date
EP1426368A1 (en) 2004-06-09
WO2002000640A1 (es) 2002-01-03
ES2177401A1 (es) 2002-12-01

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