ES2175092T3 - Preparacion de compuestos hidroxilados mediante bioconversion de dioxigenasa. - Google Patents

Preparacion de compuestos hidroxilados mediante bioconversion de dioxigenasa.

Info

Publication number
ES2175092T3
ES2175092T3 ES96914321T ES96914321T ES2175092T3 ES 2175092 T3 ES2175092 T3 ES 2175092T3 ES 96914321 T ES96914321 T ES 96914321T ES 96914321 T ES96914321 T ES 96914321T ES 2175092 T3 ES2175092 T3 ES 2175092T3
Authority
ES
Spain
Prior art keywords
formula
compound
compounds
pct
dioxigenasa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96914321T
Other languages
English (en)
Inventor
Andrew John Blacker
Derek Raymond Boyd
Howard Dalton
Nigel Bowers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avecia Ltd
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9510836.1A external-priority patent/GB9510836D0/en
Priority claimed from GBGB9511370.0A external-priority patent/GB9511370D0/en
Application filed by Avecia Ltd filed Critical Avecia Ltd
Application granted granted Critical
Publication of ES2175092T3 publication Critical patent/ES2175092T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/48—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by oxidation reactions with formation of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/14—Compounds containing azido groups with azido groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UN PROCESO PARA PREPARAR UN COMPUESTO DE FORMULA (3) EN EL QUE R SUP,2} ES -H; QUE COMPRENDE LAS ETAPAS DE: (I) CONVERTIR UN COMPUESTO DE FORMULA (1) EN UN COMPUESTO DE FORMULA (2) UTILIZANDO UN ENZIMA DIOXIGENASA; (II) CONVERSION DEL COMPUESTO DE FORMULA (2) EN UN COMPUESTO DE FORMULA (3) EN EL QUE ES -COR; Y (III) CONVERSION DEL COMPUESTO DE FORMULA (3) EN EL QUE R SUP,2} ES -COR EN UN COMPUESTO DE FORMULA (3) EN EL QUE R SUP,2} ES -H; EN EL QUE R SUP,2}, A, B, C, D, Z, M Y X SON COMO SE HA DEFINIDO EN LA REIVINDICACION 1. SE REIVINDICAN ASIMISMO ETAPAS INDIVIDUALES DEL PROCESO Y NUEVOS COMPUESTOS DE FORMULA (2).
ES96914321T 1995-05-27 1996-05-20 Preparacion de compuestos hidroxilados mediante bioconversion de dioxigenasa. Expired - Lifetime ES2175092T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9510836.1A GB9510836D0 (en) 1995-05-27 1995-05-27 Biotransformation
GBGB9511370.0A GB9511370D0 (en) 1995-06-06 1995-06-06 Biotransformation

Publications (1)

Publication Number Publication Date
ES2175092T3 true ES2175092T3 (es) 2002-11-16

Family

ID=26307103

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96914321T Expired - Lifetime ES2175092T3 (es) 1995-05-27 1996-05-20 Preparacion de compuestos hidroxilados mediante bioconversion de dioxigenasa.

Country Status (11)

Country Link
US (1) US6087137A (es)
EP (1) EP0828848B1 (es)
JP (1) JP4347906B2 (es)
AT (1) ATE215126T1 (es)
AU (1) AU5772596A (es)
CA (1) CA2216248A1 (es)
DE (1) DE69620170T2 (es)
DK (1) DK0828848T3 (es)
ES (1) ES2175092T3 (es)
PT (1) PT828848E (es)
WO (1) WO1996037628A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179932B2 (en) * 2002-06-03 2007-02-20 Genencor International, Inc. Synthesis of cis-diols from aryl silanes

Also Published As

Publication number Publication date
EP0828848B1 (en) 2002-03-27
WO1996037628A1 (en) 1996-11-28
DK0828848T3 (da) 2002-07-15
DE69620170T2 (de) 2002-11-07
ATE215126T1 (de) 2002-04-15
CA2216248A1 (en) 1996-11-28
AU5772596A (en) 1996-12-11
EP0828848A1 (en) 1998-03-18
US6087137A (en) 2000-07-11
DE69620170D1 (de) 2002-05-02
JPH11511655A (ja) 1999-10-12
JP4347906B2 (ja) 2009-10-21
PT828848E (pt) 2002-07-31

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