ES2172482B1 - Adicion de la patente es200100402 "vacuna para la proteccion de perros frente a la leishmania". - Google Patents
Adicion de la patente es200100402 "vacuna para la proteccion de perros frente a la leishmania".Info
- Publication number
- ES2172482B1 ES2172482B1 ES200102057A ES200102057A ES2172482B1 ES 2172482 B1 ES2172482 B1 ES 2172482B1 ES 200102057 A ES200102057 A ES 200102057A ES 200102057 A ES200102057 A ES 200102057A ES 2172482 B1 ES2172482 B1 ES 2172482B1
- Authority
- ES
- Spain
- Prior art keywords
- vaccine
- leishmania
- addition
- protection
- against leishmania
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 241000222722 Leishmania <genus> Species 0.000 title abstract 3
- 241000282472 Canis lupus familiaris Species 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 241000222697 Leishmania infantum Species 0.000 abstract 1
- 241001137872 Leishmania sp. Species 0.000 abstract 1
- 208000004554 Leishmaniasis Diseases 0.000 abstract 1
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/008—Leishmania antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Adición de la patente ES200100402 vacuna para la protección de perros frente a Leishmania. La presente adición se relaciona, en general, con la prevención de la Leishmaniasis en animales, en particular, con una vacuna para proteger animales, perros entre otros, de la infección causada por Leishmania sp., que comprende la proteína P36 de Leishmania infantum, o un fragmento inmunogénico de la misma, o bien un sistema de expresión de dicha proteína o fragmento, opcionalmente junto con un compuesto que estimula la producción de una respuesta inmune celular de tipo Th1; así como varios protocolos de vacunación frente a Leishmania sp a partir del empleo de dicha vacuna.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT02702414T PT1371375E (pt) | 2001-02-21 | 2002-02-21 | Vacina para a protecção de animais contra a leishmaníase âmbito técnico |
ES02702414T ES2334493T3 (es) | 2001-02-21 | 2002-02-21 | Vacuna para la proteccion de animales frente a leishmania. |
AT02702414T ATE439858T1 (de) | 2001-02-21 | 2002-02-21 | Vakzine zum schutz von tieren gegen leishmania |
EP02702414A EP1371375B1 (en) | 2001-02-21 | 2002-02-21 | Vaccine to protect animals against leishmania |
US10/468,618 US8986711B2 (en) | 2001-02-21 | 2002-02-21 | Vaccine to protect animals against leishmania |
DE60233391T DE60233391D1 (de) | 2001-02-21 | 2002-02-21 | Vakzine zum schutz von tieren gegen leishmania |
PCT/ES2002/000077 WO2002066054A1 (es) | 2001-02-21 | 2002-02-21 | Vacuna para la protección de animales frente a leishmania |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200100402A ES2171360B1 (es) | 2001-02-21 | 2001-02-21 | Vacuna para la proteccion de animales frente a la leishmania. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2172482A1 ES2172482A1 (es) | 2003-07-16 |
ES2172482B1 true ES2172482B1 (es) | 2004-12-01 |
Family
ID=8496822
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200100402A Expired - Fee Related ES2171360B1 (es) | 2001-02-21 | 2001-02-21 | Vacuna para la proteccion de animales frente a la leishmania. |
ES200102057A Expired - Fee Related ES2172482B1 (es) | 2001-02-21 | 2001-09-12 | Adicion de la patente es200100402 "vacuna para la proteccion de perros frente a la leishmania". |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200100402A Expired - Fee Related ES2171360B1 (es) | 2001-02-21 | 2001-02-21 | Vacuna para la proteccion de animales frente a la leishmania. |
Country Status (2)
Country | Link |
---|---|
US (1) | US8986711B2 (es) |
ES (2) | ES2171360B1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2313807B1 (es) * | 2005-07-30 | 2009-12-23 | Consejo Superior De Investigaciones Cientificas | Vectores recombinantes basados en el virus vaccinia modificado de ankara (mva) como vacunas contra la leishmaniasis. |
-
2001
- 2001-02-21 ES ES200100402A patent/ES2171360B1/es not_active Expired - Fee Related
- 2001-09-12 ES ES200102057A patent/ES2172482B1/es not_active Expired - Fee Related
-
2002
- 2002-02-21 US US10/468,618 patent/US8986711B2/en not_active Expired - Fee Related
Non-Patent Citations (4)
Title |
---|
GONZÁLEZ ASEGUINOLAZA et al. "Molecular cloning, cell localization and binding affinity to DNA replication proteins of the p36/LACK protective antigen from Leishmania infantum". 1999. Eur. J. Biochem., Vol. 259, páginas 909-916. * |
GURUNATHAN et al. "Vaccination with DNA encoding the immuno-dominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major". Octubre 1997. The Journal of Experimental Medicine. Vol. 186 (7), páginas 1137-1147. * |
MATTNER et al. "Interleukin-12 is indispensable for protective immunity against Leishmania major". Noviembre 1997. Infect. Immun., Vol. 65 (11), páginas 4378-4383. * |
RAJA GABAGLIA et al. "A single intramuscular injection with adenovirus expressing IL-12 protects BALB/c mice against Leishmania major infection, while treatement whit an IL-4 expressing vector increases disease susceptibility in B10.D2 mice". 1999. J. Immunol., Vol. 162, páginas 753-760. * |
Also Published As
Publication number | Publication date |
---|---|
ES2172482A1 (es) | 2003-07-16 |
ES2171360B1 (es) | 2003-12-16 |
US20040156866A1 (en) | 2004-08-12 |
US8986711B2 (en) | 2015-03-24 |
ES2171360A1 (es) | 2002-09-01 |
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Legal Events
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