ES2172071T3 - Derivados de piperidina como ltd4 y de h1. - Google Patents

Derivados de piperidina como ltd4 y de h1.

Info

Publication number
ES2172071T3
ES2172071T3 ES98118065T ES98118065T ES2172071T3 ES 2172071 T3 ES2172071 T3 ES 2172071T3 ES 98118065 T ES98118065 T ES 98118065T ES 98118065 T ES98118065 T ES 98118065T ES 2172071 T3 ES2172071 T3 ES 2172071T3
Authority
ES
Spain
Prior art keywords
chem
single bond
piperidine
present
ltd4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98118065T
Other languages
English (en)
Inventor
Hendrik Timmerman
Mingqiang Zang
Kazuhiro Onogi
Yoshio Takahashi
Masahiro Tamura
Tsutomu Tohma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Application granted granted Critical
Publication of ES2172071T3 publication Critical patent/ES2172071T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN DERIVADO DE PIPERIDINA REPRESENTADO MEDIANTE LA SIGUIENTE FORMULA (1) O A UNA SAL DEL MISMO: DONDE R 1 , R 2 Y R 3 REPRESENTAN INDIVIDUALMENTE ATOMOS DE HIDROGENO, ETC., Y REPRESENTA: B REPRESENTA UN ENLACE SENCILLO, UN GRUPO ALQUILENO, - S CH 2 - O - CH = CH -, E REPRESENTA UN ENLACE SENCILLO O UN GRUPO TRIMETILENO, Z REPRESENTA UN ATOMO DE OXIGENO, ETC., Y N REPRESENTA UN NUMERO ENTRE 2 Y 5 INCLUSIVE. LA INVENCION DESCRIBE TAMBIEN UN MEDICAMENTO QUE CONTIENE DICHO COMPUESTO. EL MEDICAMENTO DESCRITO EN LA PRESENTE INVENCION ESTA DOTADO DE UNA ACTIVIDAD ANTIHISTAMINICA Y ANTILEUCOTRIENO EXCELENTE Y PRESENTA EFECTOS SECUNDARIOS REDUCIDOS, COMO LA SOMNOLENCIA.
ES98118065T 1997-09-25 1998-09-23 Derivados de piperidina como ltd4 y de h1. Expired - Lifetime ES2172071T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25984897 1997-09-25
JP26159997 1997-09-26

Publications (1)

Publication Number Publication Date
ES2172071T3 true ES2172071T3 (es) 2002-09-16

Family

ID=26544316

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98118065T Expired - Lifetime ES2172071T3 (es) 1997-09-25 1998-09-23 Derivados de piperidina como ltd4 y de h1.

Country Status (6)

Country Link
US (1) US6107308A (es)
EP (1) EP0905134B1 (es)
KR (1) KR100535324B1 (es)
AT (1) ATE212021T1 (es)
DE (1) DE69803151T2 (es)
ES (1) ES2172071T3 (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5041453A (en) * 1990-05-30 1991-08-20 Rhone-Poulenc Rorer Pharmaceuticals Inc. Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4
JP3193508B2 (ja) * 1993-03-05 2001-07-30 興和株式会社 ピペリジン誘導体
US5756518A (en) * 1996-04-02 1998-05-26 Kowa Co., Ltd. Phenylene derivatives
DE19629670A1 (de) * 1996-07-23 1998-01-29 Friedolf Mutschler Verfahren und Vorrichtung zur Lenkung des Sonnenlichtes und Temperaturregelung

Also Published As

Publication number Publication date
EP0905134A1 (en) 1999-03-31
US6107308A (en) 2000-08-22
DE69803151D1 (de) 2002-02-21
ATE212021T1 (de) 2002-02-15
EP0905134B1 (en) 2002-01-16
DE69803151T2 (de) 2002-08-14
KR19990029946A (ko) 1999-04-26
KR100535324B1 (ko) 2006-04-21

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