ES2171665T3 - Derivados y conjugados de mdp que tienen una actividad que estimula la funcion hematopoyetica y las composiciones que contienen los mismos. - Google Patents

Derivados y conjugados de mdp que tienen una actividad que estimula la funcion hematopoyetica y las composiciones que contienen los mismos.

Info

Publication number
ES2171665T3
ES2171665T3 ES96912079T ES96912079T ES2171665T3 ES 2171665 T3 ES2171665 T3 ES 2171665T3 ES 96912079 T ES96912079 T ES 96912079T ES 96912079 T ES96912079 T ES 96912079T ES 2171665 T3 ES2171665 T3 ES 2171665T3
Authority
ES
Spain
Prior art keywords
function
hematopoyetic
conjugates
stimulates
themselves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96912079T
Other languages
English (en)
Inventor
Georges Bahr
Pierre Lefrancier
Louis Chedid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vacsyn SA
Original Assignee
Vacsyn SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vacsyn SA filed Critical Vacsyn SA
Application granted granted Critical
Publication of ES2171665T3 publication Critical patent/ES2171665T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

COMPOSICION FARMACEUTICA DESTINADA A ESTIMULAR LA FUNCION HEMATOPOYETICA Y PREVENIR LOS EFECTOS MIELOTOXICOS DE CIERTOS TRATAMIENTOS QUE CONTIENEN AL MENOS UN DERIVADO HIDROSOLUBLE DE MURAMIL PEPTIDO, COMO POR EJEMPLO EL MURADIMETIDO, LA MUROCTASINA O EL MTP
ES96912079T 1995-04-07 1996-04-05 Derivados y conjugados de mdp que tienen una actividad que estimula la funcion hematopoyetica y las composiciones que contienen los mismos. Expired - Lifetime ES2171665T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9504194A FR2732604B1 (fr) 1995-04-07 1995-04-07 Derives et conjugues du mdp presentant une activite stimulatrice de la fonction hematopoietique et compositions les contenant

Publications (1)

Publication Number Publication Date
ES2171665T3 true ES2171665T3 (es) 2002-09-16

Family

ID=9477896

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96912079T Expired - Lifetime ES2171665T3 (es) 1995-04-07 1996-04-05 Derivados y conjugados de mdp que tienen una actividad que estimula la funcion hematopoyetica y las composiciones que contienen los mismos.

Country Status (11)

Country Link
EP (1) EP0819136B1 (es)
JP (2) JP3816522B2 (es)
AT (1) ATE212644T1 (es)
AU (1) AU5504696A (es)
CA (1) CA2216599A1 (es)
DE (1) DE69618942T2 (es)
DK (1) DK0819136T3 (es)
ES (1) ES2171665T3 (es)
FR (1) FR2732604B1 (es)
PT (1) PT819136E (es)
WO (1) WO1996031533A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618673D0 (en) * 1996-09-06 1996-10-16 Peptech Uk Ltd The use of muramyl peptides
PE20100362A1 (es) * 2008-10-30 2010-05-27 Irm Llc Derivados de purina que expanden las celulas madre hematopoyeticas
WO2012026712A2 (ko) * 2010-08-23 2012-03-01 주식회사 강스템홀딩스 Ｎｏｄ２의 아고니스트를 처리한 줄기세포 또는 그 배양물을 포함하는 면역질환 또는 염증질환의 예방 또는 치료용 약학조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2343483A1 (fr) * 1976-03-10 1977-10-07 Anvar L'ester methylique de la 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-isoglutamine et le diester methylique de l'acide 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-glutamique et medicaments les contenant
FR2522967B1 (fr) * 1982-03-15 1986-03-07 Anvar Conjugues d'haptenes et de muramyl-peptides, doues d'activite immunogene et compositions les contenant
FI79330C (fi) * 1982-07-23 1989-12-11 Ciba Geigy Ag Foerfarande foer framstaellning av farmakologiskt verkande muramylpeptid-n-(2-fosfatidyloxietyl)-amider.
EP0192609A3 (de) * 1985-02-20 1988-04-27 Ciba-Geigy Ag Acylierte Hexosederivate und Verfahren zu ihrer Herstellung
FR2715305B1 (fr) * 1994-01-25 1996-03-15 Vacsyn Sa Diesters de muramyl peptides dans une forme orale.

Also Published As

Publication number Publication date
FR2732604B1 (fr) 1997-06-06
JP2006182785A (ja) 2006-07-13
JPH11503426A (ja) 1999-03-26
AU5504696A (en) 1996-10-23
PT819136E (pt) 2002-07-31
FR2732604A1 (fr) 1996-10-11
EP0819136B1 (fr) 2002-01-30
DE69618942D1 (de) 2002-03-14
ATE212644T1 (de) 2002-02-15
JP3816522B2 (ja) 2006-08-30
WO1996031533A1 (fr) 1996-10-10
EP0819136A1 (fr) 1998-01-21
DK0819136T3 (da) 2002-05-21
DE69618942T2 (de) 2002-09-19
CA2216599A1 (fr) 1996-10-10

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