ATE212644T1 - Derivate und konjugete von mdp, eine von hämatopoitischer funktion stimulierende wirkung und deren enthaltende zusammensetzungen - Google Patents

Derivate und konjugete von mdp, eine von hämatopoitischer funktion stimulierende wirkung und deren enthaltende zusammensetzungen

Info

Publication number
ATE212644T1
ATE212644T1 AT96912079T AT96912079T ATE212644T1 AT E212644 T1 ATE212644 T1 AT E212644T1 AT 96912079 T AT96912079 T AT 96912079T AT 96912079 T AT96912079 T AT 96912079T AT E212644 T1 ATE212644 T1 AT E212644T1
Authority
AT
Austria
Prior art keywords
conjugets
mdp
derivatives
compositions containing
stimulating action
Prior art date
Application number
AT96912079T
Other languages
English (en)
Inventor
Georges Bahr
Pierre Lefrancier
Louis Chedid
Original Assignee
Vacsyn Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vacsyn Sa filed Critical Vacsyn Sa
Application granted granted Critical
Publication of ATE212644T1 publication Critical patent/ATE212644T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT96912079T 1995-04-07 1996-04-05 Derivate und konjugete von mdp, eine von hämatopoitischer funktion stimulierende wirkung und deren enthaltende zusammensetzungen ATE212644T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9504194A FR2732604B1 (fr) 1995-04-07 1995-04-07 Derives et conjugues du mdp presentant une activite stimulatrice de la fonction hematopoietique et compositions les contenant
PCT/FR1996/000527 WO1996031533A1 (fr) 1995-04-07 1996-04-05 Derives et conjugues du mdp presentant une activite stimulatrice de la fonction hematopoietique et composition les contenant

Publications (1)

Publication Number Publication Date
ATE212644T1 true ATE212644T1 (de) 2002-02-15

Family

ID=9477896

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96912079T ATE212644T1 (de) 1995-04-07 1996-04-05 Derivate und konjugete von mdp, eine von hämatopoitischer funktion stimulierende wirkung und deren enthaltende zusammensetzungen

Country Status (11)

Country Link
EP (1) EP0819136B1 (de)
JP (2) JP3816522B2 (de)
AT (1) ATE212644T1 (de)
AU (1) AU5504696A (de)
CA (1) CA2216599A1 (de)
DE (1) DE69618942T2 (de)
DK (1) DK0819136T3 (de)
ES (1) ES2171665T3 (de)
FR (1) FR2732604B1 (de)
PT (1) PT819136E (de)
WO (1) WO1996031533A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618673D0 (en) * 1996-09-06 1996-10-16 Peptech Uk Ltd The use of muramyl peptides
PE20100362A1 (es) * 2008-10-30 2010-05-27 Irm Llc Derivados de purina que expanden las celulas madre hematopoyeticas
US9408873B2 (en) 2010-08-23 2016-08-09 Kang Stem Biotech Co., Ltd. Pharmaceutical composition comprising stem cells treated with NOD2 agonist or culture thereof for prevention and treatment of immune disorders and inflammatory diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2343483A1 (fr) * 1976-03-10 1977-10-07 Anvar L'ester methylique de la 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-isoglutamine et le diester methylique de l'acide 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-glutamique et medicaments les contenant
FR2522967B1 (fr) * 1982-03-15 1986-03-07 Anvar Conjugues d'haptenes et de muramyl-peptides, doues d'activite immunogene et compositions les contenant
EP0099578B1 (de) * 1982-07-23 1986-11-12 Ciba-Geigy Ag Neue Muramylpeptide und Verfahren zu ihrer Herstellung
EP0192609A3 (de) * 1985-02-20 1988-04-27 Ciba-Geigy Ag Acylierte Hexosederivate und Verfahren zu ihrer Herstellung
FR2715305B1 (fr) * 1994-01-25 1996-03-15 Vacsyn Sa Diesters de muramyl peptides dans une forme orale.

Also Published As

Publication number Publication date
JPH11503426A (ja) 1999-03-26
DE69618942D1 (de) 2002-03-14
ES2171665T3 (es) 2002-09-16
AU5504696A (en) 1996-10-23
EP0819136B1 (de) 2002-01-30
EP0819136A1 (de) 1998-01-21
CA2216599A1 (fr) 1996-10-10
DE69618942T2 (de) 2002-09-19
DK0819136T3 (da) 2002-05-21
WO1996031533A1 (fr) 1996-10-10
PT819136E (pt) 2002-07-31
FR2732604B1 (fr) 1997-06-06
FR2732604A1 (fr) 1996-10-11
JP2006182785A (ja) 2006-07-13
JP3816522B2 (ja) 2006-08-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee