ES2170222T3 - Derivados c-nucleosidos y su utilizacion en la deteccion de acidos nucleicos. - Google Patents

Derivados c-nucleosidos y su utilizacion en la deteccion de acidos nucleicos.

Info

Publication number
ES2170222T3
ES2170222T3 ES96905870T ES96905870T ES2170222T3 ES 2170222 T3 ES2170222 T3 ES 2170222T3 ES 96905870 T ES96905870 T ES 96905870T ES 96905870 T ES96905870 T ES 96905870T ES 2170222 T3 ES2170222 T3 ES 2170222T3
Authority
ES
Spain
Prior art keywords
nucleic acids
derivatives
nucleosid
detection
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96905870T
Other languages
English (en)
Inventor
Klaus Muhlegger
Der Eltz Herbert Von
Frank Seela
Helmut Rosemeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2170222T3 publication Critical patent/ES2170222T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION TRATA DE PIRROLO RAZOLO DECIR, LOS ASI LLAMADOS C (I) DIMIENTO PARA SU FABRICACION. LAS COMPOSICIONES SON ESPECIALMENTE APTAS COMO SUSTRATOS PARA POLIMERASAS EN SER INCORPORADAS A LOS OLIGONUCLEOTIDOS PUES, ESTAS COMPOSICIONES SON ESPECIALMENTE APTAS PARA MARCAR Y DETECTAR ACIDOS NUCLEINICOS Y PARA LA SECUENCIACION DE DNA.
ES96905870T 1995-03-14 1996-03-12 Derivados c-nucleosidos y su utilizacion en la deteccion de acidos nucleicos. Expired - Lifetime ES2170222T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19509038A DE19509038A1 (de) 1995-03-14 1995-03-14 C-Nukleosid-Derivate und deren Verwendung in der Detektion von Nukleinsäuren

Publications (1)

Publication Number Publication Date
ES2170222T3 true ES2170222T3 (es) 2002-08-01

Family

ID=7756550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96905870T Expired - Lifetime ES2170222T3 (es) 1995-03-14 1996-03-12 Derivados c-nucleosidos y su utilizacion en la deteccion de acidos nucleicos.

Country Status (7)

Country Link
EP (1) EP0815117B1 (es)
JP (1) JP3639308B2 (es)
AT (1) ATE211481T1 (es)
CA (1) CA2215176C (es)
DE (2) DE19509038A1 (es)
ES (1) ES2170222T3 (es)
WO (1) WO1996028460A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US7282327B2 (en) 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US7423143B2 (en) 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US7468243B2 (en) 2001-03-12 2008-12-23 Affymetrix, Inc. 2-aminopyrimidin-4-one nucleic acid labeling compounds
US7291463B2 (en) 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US6864059B2 (en) 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US20010018514A1 (en) 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
US7572582B2 (en) 1997-09-12 2009-08-11 Exiqon A/S Oligonucleotide analogues
FR2780059B1 (fr) * 1998-06-17 2002-10-11 Bio Merieux Procede de marquage d'un acide ribonucleique et fragments d'arn marques ainsi obtenus
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
WO2003011885A1 (en) * 2001-07-25 2003-02-13 Celltech R & D Limited Non-natural carbon-linked nucleotides and dinucleotides
AU2003217311A1 (en) * 2002-02-06 2003-09-02 Pierce Milwaukee Llc Base-labeled nucleosides and nucleotides
WO2005049849A2 (en) 2003-11-14 2005-06-02 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
WO2006127507A2 (en) 2005-05-20 2006-11-30 Integrated Dna Technologies, Inc. Compounds and methods for labeling oligonucleotides
GB0718255D0 (en) * 2007-09-19 2007-10-31 Univ Edinburgh Nucleobase characterisation
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2553123B1 (en) 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Methods for enhancing nucleic acid hybridization
EP2896696B1 (en) 2010-09-07 2017-12-27 Integrated Dna Technologies, Inc. Modifications for antisense compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584369A (en) * 1981-07-31 1986-04-22 Sloan-Kettering Institute For Cancer Research Anti-leukemic beta-glycosyl C-nucleosides
JP2688759B2 (ja) * 1988-02-16 1997-12-10 大塚製薬株式会社 シュードウリジン誘導体
JPH02196787A (ja) * 1989-01-25 1990-08-03 Otsuka Pharmaceut Co Ltd シュードウリジン誘導体
CA2129105A1 (en) * 1992-02-12 1993-08-19 Michael J. Conrad Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides
IL107616A0 (en) * 1992-11-18 1994-02-27 Univ Johns Hopkins Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs
JPH09505556A (ja) * 1993-08-18 1997-06-03 クロマジェン インク 蛍光性ｎ−ヌクレオシド及び蛍光性ｎ−ヌクレオシド構造類似体の応用

Also Published As

Publication number Publication date
DE19509038A1 (de) 1996-09-19
CA2215176C (en) 2008-01-15
EP0815117A1 (de) 1998-01-07
DE59608542D1 (de) 2002-02-07
EP0815117B1 (de) 2002-01-02
CA2215176A1 (en) 1996-09-19
JPH11503306A (ja) 1999-03-26
WO1996028460A1 (de) 1996-09-19
JP3639308B2 (ja) 2005-04-20
ATE211481T1 (de) 2002-01-15

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