ES2166146T3 - Formulacion de particulas estabilizadas de agente(s) de transfeccion cationico(s)/acidos nucleicos. - Google Patents

Formulacion de particulas estabilizadas de agente(s) de transfeccion cationico(s)/acidos nucleicos.

Info

Publication number
ES2166146T3
ES2166146T3 ES98906986T ES98906986T ES2166146T3 ES 2166146 T3 ES2166146 T3 ES 2166146T3 ES 98906986 T ES98906986 T ES 98906986T ES 98906986 T ES98906986 T ES 98906986T ES 2166146 T3 ES2166146 T3 ES 2166146T3
Authority
ES
Spain
Prior art keywords
nucleic acids
formulation
transfection agent
cationic transfection
stabilized particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98906986T
Other languages
English (en)
Inventor
Joel Crouzet
Bruno Pitard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9503492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2166146(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of ES2166146T3 publication Critical patent/ES2166146T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Abstract

Composición caracterizada porque comprende partículas de complejos laminares agente(s)de transfección catiónico(s)/ácidos nucleicos y porque comprende al menos un agente con actividad superficial no iónico en cantidad comprendida entre 0,01 % y 10 % peso/volumen a fn de obtener complejos laminares estabilizados con un diámetro inferior o igual a 160 nm.
ES98906986T 1997-02-10 1998-02-06 Formulacion de particulas estabilizadas de agente(s) de transfeccion cationico(s)/acidos nucleicos. Expired - Lifetime ES2166146T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9701467A FR2759298B1 (fr) 1997-02-10 1997-02-10 Formulation de particules agent(s) de transfection cationique(s)/acides nucleiques stabilisees

Publications (1)

Publication Number Publication Date
ES2166146T3 true ES2166146T3 (es) 2002-04-01

Family

ID=9503492

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98906986T Expired - Lifetime ES2166146T3 (es) 1997-02-10 1998-02-06 Formulacion de particulas estabilizadas de agente(s) de transfeccion cationico(s)/acidos nucleicos.

Country Status (20)

Country Link
EP (1) EP1007097B1 (es)
JP (1) JP2001511171A (es)
KR (1) KR20000070914A (es)
AT (1) ATE206932T1 (es)
AU (1) AU737720B2 (es)
BR (1) BR9807563A (es)
CA (1) CA2278665A1 (es)
CZ (1) CZ282199A3 (es)
DE (1) DE69802102T2 (es)
DK (1) DK1007097T3 (es)
ES (1) ES2166146T3 (es)
FR (1) FR2759298B1 (es)
GR (1) GR3036919T3 (es)
HU (1) HUP0001720A3 (es)
IL (1) IL130765A0 (es)
NO (1) NO993825L (es)
PT (1) PT1007097E (es)
SK (1) SK282685B6 (es)
WO (1) WO1998034648A1 (es)
ZA (1) ZA981034B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6359054B1 (en) * 1994-11-18 2002-03-19 Supratek Pharma Inc. Polynucleotide compositions for intramuscular administration
AU768542C (en) * 1998-04-08 2004-06-17 Celltech R & D Limited Lipids
CA2335393C (en) * 1998-07-20 2008-09-23 Inex Pharmaceuticals Corporation Liposomal encapsulated nucleic acid-complexes
EP1309904A4 (en) * 2000-03-03 2006-03-29 Valentis Inc IMPROVED POLOXAMER AND POLYOAMINE COMPOUNDS FOR NUCLEINE SUCTION INTRODUCTION
GB0009201D0 (en) * 2000-04-14 2000-05-31 Univ Nottingham Cationic polymer - Nucleic acid complexes and methods of making them
US20020091242A1 (en) 2000-10-11 2002-07-11 Michel Bessodes Acid-sensitive compounds, their preparation and uses
CA2426582A1 (en) * 2000-10-20 2002-08-08 Valentis, Inc. Gene delivery formulations and methods for treatment of ischemic conditions
EP1232758A1 (fr) * 2001-02-19 2002-08-21 Aventis Pasteur Polynucléotide formulé en vue d'un transfert intracellulaire amélioré
WO2005120546A2 (en) * 2004-03-03 2005-12-22 Essentia Biosystems, Inc. Compositions and methods for topical diagnostic and therapeutic transport
US9211248B2 (en) 2004-03-03 2015-12-15 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
JP2008531732A (ja) 2005-03-03 2008-08-14 ルバンス セラピュティックス インク． ボツリヌス毒素の局所塗布及び経皮送達のための組成物及び方法
JP4653242B1 (ja) 2010-02-12 2011-03-16 ナノキャリア株式会社 粒子状医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1181937A3 (en) * 1994-08-09 2004-02-04 Cytrx Corporation Novel vaccine adjuvant and vaccine
AU5527696A (en) * 1995-03-31 1996-10-16 Children's Hospital Medical Center Use of surfactants for introducing genetic material into lun g cells
US6120794A (en) * 1995-09-26 2000-09-19 University Of Pittsburgh Emulsion and micellar formulations for the delivery of biologically active substances to cells

Also Published As

Publication number Publication date
DE69802102D1 (de) 2001-11-22
HUP0001720A3 (en) 2001-10-29
BR9807563A (pt) 2000-02-01
HUP0001720A1 (hu) 2000-09-28
CA2278665A1 (fr) 1998-08-13
CZ282199A3 (cs) 1999-10-13
SK108299A3 (en) 2000-05-16
ZA981034B (en) 1998-08-11
KR20000070914A (ko) 2000-11-25
DK1007097T3 (da) 2002-02-11
FR2759298A1 (fr) 1998-08-14
PT1007097E (pt) 2002-04-29
NO993825D0 (no) 1999-08-09
EP1007097A1 (fr) 2000-06-14
GR3036919T3 (en) 2002-01-31
AU6298798A (en) 1998-08-26
JP2001511171A (ja) 2001-08-07
WO1998034648A1 (fr) 1998-08-13
ATE206932T1 (de) 2001-11-15
DE69802102T2 (de) 2002-03-14
IL130765A0 (en) 2001-01-28
NO993825L (no) 1999-08-09
EP1007097B1 (fr) 2001-10-17
SK282685B6 (sk) 2002-11-06
FR2759298B1 (fr) 1999-04-09
AU737720B2 (en) 2001-08-30

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