ES2165907T3 - Procedimiento de marcado de microparticulas con acridinio y aplicacion a un instrumento. - Google Patents

Procedimiento de marcado de microparticulas con acridinio y aplicacion a un instrumento.

Info

Publication number
ES2165907T3
ES2165907T3 ES95909496T ES95909496T ES2165907T3 ES 2165907 T3 ES2165907 T3 ES 2165907T3 ES 95909496 T ES95909496 T ES 95909496T ES 95909496 T ES95909496 T ES 95909496T ES 2165907 T3 ES2165907 T3 ES 2165907T3
Authority
ES
Spain
Prior art keywords
microparticle
methods
proteinaceous compound
tosil
carboximide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95909496T
Other languages
English (en)
Inventor
Dinesh O Shah
Tarun Chandra
Kurt Klosterman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2165907T3 publication Critical patent/ES2165907T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Dental Preparations (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

CONFORMACIONES DE LA INVENCION SUMINISTRAN METODOS PARA PREPARAR UNA MICROPARTICULA DE ACRIDINIUM ACTIVADA. GENERALMENTE, LOS METODOS COMPRENDEN EL ACOPLAMIENTO COVALENTE DIRECTO O UN FORMATO DE AFINIDAD. EL METODO DE ACOPLAMIENTO COVALENTE DIRECTO COMPRENDE EL REVESTIMIENTO DE UNA MICROPARTICULA CON UN COMPUESTO PROTEINACEO. ENTONCES, SE ACOPLA UN SULFONATO DE TRIFLUOROMETANO DE CARBOXIMIDO DE 10-METIL-N-TOSIL-N-(2-CARBOXIETIL)-9-ACRIDINIUM AL COMPUESTO PROTEINACEO. EN EL FORMATO DE AFINIDAD, UNA MICROPARTICULA SE RECUBRE CON UN COMPUESTO PROTEINACEO BIOTINILADO. LA MICROPARTICULA SE HACE REACCIONAR CON SULFONATO DE TRIFLUOROMETANO DE CARBOXIMIDO DE 10-METIL-N-TOSIL-N-(2CARBOXIETIL)-9-ACRIDINIUM ETIQUETADO ANTIBIOTINA. TAMBIEN SE SUMINISTRAN METODOS PARA UTILIZAR LA MICROPARTICULA. ESTOS METODOS DE USO PUEDEN ESTIMAR LA EFICIENCIA DE TRANSFERENCIA, CALIBRAR OPTICOS Y MEDIR EL TAMAÑO DE PORO DE UNA MEMBRANA DE UN INSTRUMENTO BASADO EN QUIMIOLUMINISCENCIA. TAMBIEN SE SUMINISTRAN ELEMENTOS DEPRUEBA PARA INSTRUMENTOS ANALITICOS.
ES95909496T 1994-02-15 1995-02-06 Procedimiento de marcado de microparticulas con acridinio y aplicacion a un instrumento. Expired - Lifetime ES2165907T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/196,536 US5468649A (en) 1994-02-15 1994-02-15 Process for labeling acridinium to microparticles and application in an instrument

Publications (1)

Publication Number Publication Date
ES2165907T3 true ES2165907T3 (es) 2002-04-01

Family

ID=22725805

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95909496T Expired - Lifetime ES2165907T3 (es) 1994-02-15 1995-02-06 Procedimiento de marcado de microparticulas con acridinio y aplicacion a un instrumento.

Country Status (9)

Country Link
US (1) US5468649A (es)
EP (1) EP0745223B1 (es)
JP (1) JP3580821B2 (es)
AT (1) ATE206523T1 (es)
AU (1) AU1744395A (es)
CA (1) CA2179310A1 (es)
DE (1) DE69523040T2 (es)
ES (1) ES2165907T3 (es)
WO (1) WO1995022059A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022533A1 (en) * 1995-01-18 1996-07-25 First Medical, Inc. Method for immobilizing haptens on a test article
US5650334A (en) * 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
WO1997040385A1 (en) 1996-04-25 1997-10-30 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7190522B2 (en) 2002-09-12 2007-03-13 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
AU2003265583C1 (en) 2002-08-20 2009-05-21 Cyvera Corporation Diffraction grating-based optical identification element
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
EP1540592A1 (en) 2002-09-12 2005-06-15 Cyvera Corporation Method and apparatus for labeling using diffraction grating-based encoded optical identification elements
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
WO2004025563A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
WO2004024328A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
JP4564959B2 (ja) * 2003-09-22 2010-10-20 バイオアレイ ソリューションズ リミテッド 生体分子に共有結合できる、複数の官能基を持つ表面固定化高分子電解質
CA2899287A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
WO2006020363A2 (en) 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
EP2194485B1 (en) 2004-11-16 2012-10-17 Illumina, Inc. Method and apparatus for reading coded microbeads
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US7858924B2 (en) 2006-12-12 2010-12-28 Abbott Laboratories, Inc. Device for use in normalizing readings on a testing machine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351824A (en) * 1981-02-05 1982-09-28 Icl Scientific Polystyrene latex reagents, methods of preparation, and use in immunological procedures
JPS6036962A (ja) * 1983-08-09 1985-02-26 Toray Ind Inc 生物学的検査用微粒子
US4774189A (en) * 1984-12-24 1988-09-27 Flow Cytometry Standards Corp. Fluorescent calibration microbeads simulating stained cells
ATE111083T1 (de) * 1986-10-22 1994-09-15 Abbott Lab Chemilumineszierende acridinium- und phenantridiniumsalze.
US5132242A (en) * 1987-07-15 1992-07-21 Cheung Sau W Fluorescent microspheres and methods of using them
US5089424A (en) * 1988-06-14 1992-02-18 Abbott Laboratories Method and apparatus for heterogeneous chemiluminescence assay

Also Published As

Publication number Publication date
CA2179310A1 (en) 1995-08-17
DE69523040D1 (de) 2001-11-08
JPH09509253A (ja) 1997-09-16
EP0745223B1 (en) 2001-10-04
WO1995022059A1 (en) 1995-08-17
ATE206523T1 (de) 2001-10-15
JP3580821B2 (ja) 2004-10-27
EP0745223A1 (en) 1996-12-04
US5468649A (en) 1995-11-21
AU1744395A (en) 1995-08-29
DE69523040T2 (de) 2002-06-27

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