ES2163473T3 - Procedimiento estereoselectivo para la preparacion de tropanamina endo y compuestos similares. - Google Patents

Procedimiento estereoselectivo para la preparacion de tropanamina endo y compuestos similares.

Info

Publication number
ES2163473T3
ES2163473T3 ES95304440T ES95304440T ES2163473T3 ES 2163473 T3 ES2163473 T3 ES 2163473T3 ES 95304440 T ES95304440 T ES 95304440T ES 95304440 T ES95304440 T ES 95304440T ES 2163473 T3 ES2163473 T3 ES 2163473T3
Authority
ES
Spain
Prior art keywords
tropanamine
endo
preparation
similar compounds
stereoselective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95304440T
Other languages
English (en)
Inventor
John Mcneill Mcgill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2163473T3 publication Critical patent/ES2163473T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Control Of Combustion (AREA)
  • External Artificial Organs (AREA)

Abstract

SE PRESENTA UN PROCESO ESTEREOSELECTIVO PARA FORMAR COMPUESTOS RELACIONADOS CON LA 4-ENDOTRAPANAMINA A TRAVES DE LA AMINACION REACTIVA DE UNA QUETONA CORRESPONDIENTE CON UN BOROHIDRURO DE TRIACILOXIDO.
ES95304440T 1994-06-27 1995-06-23 Procedimiento estereoselectivo para la preparacion de tropanamina endo y compuestos similares. Expired - Lifetime ES2163473T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26599294A 1994-06-27 1994-06-27

Publications (1)

Publication Number Publication Date
ES2163473T3 true ES2163473T3 (es) 2002-02-01

Family

ID=23012719

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95304440T Expired - Lifetime ES2163473T3 (es) 1994-06-27 1995-06-23 Procedimiento estereoselectivo para la preparacion de tropanamina endo y compuestos similares.

Country Status (10)

Country Link
US (1) US5625065A (es)
EP (1) EP0690055B1 (es)
JP (1) JPH0853445A (es)
AT (1) ATE208775T1 (es)
CA (1) CA2152312A1 (es)
DE (1) DE69523824T2 (es)
DK (1) DK0690055T3 (es)
ES (1) ES2163473T3 (es)
PT (1) PT690055E (es)
SI (1) SI0690055T1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7219073B1 (en) * 1999-08-03 2007-05-15 Brandnamestores.Com Method for extracting information utilizing a user-context-based search engine
IT1313660B1 (it) * 1999-10-01 2002-09-09 Dompe Spa Procedimento stereoselettivo per la preparazione di endo-3-amminoazabicicloalcani.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
US4432983A (en) * 1981-04-30 1984-02-21 Research Corporation Conformationally restricted histamine H2 -receptor antagonists containing a tropane ring
US4921982A (en) * 1988-07-21 1990-05-01 Eli Lilly And Company 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists

Also Published As

Publication number Publication date
PT690055E (pt) 2002-03-28
EP0690055B1 (en) 2001-11-14
ATE208775T1 (de) 2001-11-15
DE69523824T2 (de) 2002-06-13
US5625065A (en) 1997-04-29
EP0690055A1 (en) 1996-01-03
DE69523824D1 (de) 2001-12-20
DK0690055T3 (da) 2002-03-11
CA2152312A1 (en) 1995-12-28
SI0690055T1 (en) 2002-06-30
JPH0853445A (ja) 1996-02-27

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