ES2159740T3 - Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. - Google Patents

Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias.

Info

Publication number
ES2159740T3
ES2159740T3 ES96917214T ES96917214T ES2159740T3 ES 2159740 T3 ES2159740 T3 ES 2159740T3 ES 96917214 T ES96917214 T ES 96917214T ES 96917214 T ES96917214 T ES 96917214T ES 2159740 T3 ES2159740 T3 ES 2159740T3
Authority
ES
Spain
Prior art keywords
particles
compositions
fatty acid
unsaturated
saturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96917214T
Other languages
English (en)
Inventor
David W Yesair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomolecular Products Inc
Original Assignee
Biomolecular Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomolecular Products Inc filed Critical Biomolecular Products Inc
Application granted granted Critical
Publication of ES2159740T3 publication Critical patent/ES2159740T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UNA COMPOSICION DE PARTICULAS COLOIDALES LIPIDICAS MIXTAS QUE CONTIENE ACIDOS GRASOS NO ESTERIFICADOS QUE PRESENTAN DE 8 - 24 ATOMOS DE CARBONO DEL ACIDO GRASO SATURADO, INSATURADO Y POLI - INSATURADO, MONOGLICERIDOS QUE SON MONOESTERES DE GLICEROL Y ACIDOS GRASOS QUE PRESENTAN DE 8 - 24 ATOMOS DE CARBONO DEL ACIDO GRASO SATURADO, INSATURADO Y POLI - INSATURADO, LISOFOSFATIDILCOLINA EN LA CUAL EL RADICAL DE ACIDO GRASO PRESENTA DE 8 - 24 ATOMOS DE CARBONO DEL ACIDO GRASO SATURADO, INSATURADO Y POLI - INSATURADO, Y UN AGENTE DE VALORACION. LAS COMPOSICIONES TAMBIEN PUEDEN CONTENER OPCIONALMENTE SALES BILIARES Y/O OTROS TENSIOACTIVOS COMPATIBLES DESDE EL PUNTO DE VISTA BIOLOGICO. ESTAS COMPOSICIONES FORMAN PARTICULAS COLOIDALES DE TAMAÑO SUBMICRONICO Y PUEDEN ACTUAR COMO VEHICULOS PARA TRANSPORTAR FARMACOS, FUENTES DE CALORIAS EN FORMA DE GRASAS DE ABSORCION FACIL Y SOSTENIDA, FUENTES DE GRASA POLI - INSATURADA DE FACIL ABSORCION Y/O COLINA ADMINISTRADOS POR VIA ORAL, Y COMO PARTICULAS PARA LA APLICACION TOPICA A LA PIEL. TAMBIEN SE DESCRIBEN PROCEDIMIENTOS PARA FABRICAR ESTAS PARTICULAS. TAMBIEN SE DESCRIBE EL USO DE LAS COMPOSICIONES PARA FABRICAR MEDICAMENTOS Y EL USO DE LAS COMPOSICIONES PARA LA ADMINISTRACION DE COLINA (Y DE GRASAS).
ES96917214T 1995-06-06 1996-06-06 Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. Expired - Lifetime ES2159740T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47074295A 1995-06-06 1995-06-06

Publications (1)

Publication Number Publication Date
ES2159740T3 true ES2159740T3 (es) 2001-10-16

Family

ID=23868852

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96917214T Expired - Lifetime ES2159740T3 (es) 1995-06-06 1996-06-06 Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias.

Country Status (12)

Country Link
EP (1) EP0835097B1 (es)
JP (1) JPH11506780A (es)
AT (1) ATE204746T1 (es)
AU (1) AU704351B2 (es)
CA (1) CA2222161C (es)
DE (1) DE69614855T2 (es)
DK (1) DK0835097T3 (es)
ES (1) ES2159740T3 (es)
IL (1) IL122434A (es)
NZ (1) NZ309649A (es)
PT (1) PT835097E (es)
WO (1) WO1996039120A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU771901B2 (en) * 1998-09-08 2004-04-08 Biomolecular Products, Inc. Methods and compositions for increasing intestinal absorption of fats
DE60136648D1 (de) * 2000-12-05 2009-01-02 Los Angeles Childrens Hospital Pharmazeutische zusammensetzungen von fenretinid mit erhöhter bioverfügbarkeit und verfahren zu deren verwendung
ES2581184T3 (es) * 2003-01-31 2016-09-01 Childrens Hospital Los Angeles Composiciones orales de fenretinida que tienen mayor biodisponibilidad y métodos de uso de las mismas
FR2918846B1 (fr) * 2007-07-20 2013-07-26 Isl Innovation Sante Lipides Composition alimentaire pour ameliorer la digestibilite des lipides alimentaires
JP6139781B2 (ja) * 2014-04-04 2017-05-31 国立大学法人大阪大学 リゾリン脂質受容体を活性化する物質を含有する薬剤送達促進剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE59067B1 (en) * 1985-04-02 1993-12-15 Yesair David W Composition for delivery of orally administered drugs and other substances
ATE121618T1 (de) * 1990-08-13 1995-05-15 David W Yesair Gemischte lipid-bicarbonat-kolloidale partikel zur abgabe von arzneien und kalorien.

Also Published As

Publication number Publication date
CA2222161C (en) 2002-02-05
JPH11506780A (ja) 1999-06-15
EP0835097A2 (en) 1998-04-15
IL122434A (en) 2003-07-06
DE69614855T2 (de) 2002-03-28
AU704351B2 (en) 1999-04-22
ATE204746T1 (de) 2001-09-15
IL122434A0 (en) 1998-06-15
AU5986996A (en) 1996-12-24
NZ309649A (en) 2001-03-30
PT835097E (pt) 2001-12-28
DK0835097T3 (da) 2001-10-08
WO1996039120A2 (en) 1996-12-12
DE69614855D1 (de) 2001-10-04
WO1996039120A3 (en) 1997-03-06
CA2222161A1 (en) 1996-12-12
EP0835097B1 (en) 2001-08-29

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