ES2159551T3 - Derivados de acido glutamico heterociclico condensado utilizados como agentes antiproliferativos. - Google Patents

Derivados de acido glutamico heterociclico condensado utilizados como agentes antiproliferativos.

Info

Publication number
ES2159551T3
ES2159551T3 ES94906611T ES94906611T ES2159551T3 ES 2159551 T3 ES2159551 T3 ES 2159551T3 ES 94906611 T ES94906611 T ES 94906611T ES 94906611 T ES94906611 T ES 94906611T ES 2159551 T3 ES2159551 T3 ES 2159551T3
Authority
ES
Spain
Prior art keywords
heterociclic
condensed
derivatives
glutamic acid
acid used
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906611T
Other languages
English (en)
Inventor
Michael D Varney
Cynthia L Palmer
William H Romines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agouron Pharmaceuticals LLC
Original Assignee
Agouron Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharmaceuticals LLC filed Critical Agouron Pharmaceuticals LLC
Application granted granted Critical
Publication of ES2159551T3 publication Critical patent/ES2159551T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE HAN DESCUBIERTO NUEVOS COMPUESTOS DE FORMULA (I) QUE INHIBEN LA ENZIMA GLICINAMIDA RIBONUCLEOTIDA FORMILO TRANFERASA (GARFT). TAMBIEN SE PRESENTA UN METODO NUEVO DE PREPARACION DE TALES COMPUESTOS, ASI COMO METODOS Y COMPOSICIONES PARA EMPLEAR LOS COMPUESTOS COMO AGENTES ANTIPROLIFERANTES.
ES94906611T 1993-01-29 1994-01-18 Derivados de acido glutamico heterociclico condensado utilizados como agentes antiproliferativos. Expired - Lifetime ES2159551T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1086193A 1993-01-29 1993-01-29

Publications (1)

Publication Number Publication Date
ES2159551T3 true ES2159551T3 (es) 2001-10-16

Family

ID=21747775

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906611T Expired - Lifetime ES2159551T3 (es) 1993-01-29 1994-01-18 Derivados de acido glutamico heterociclico condensado utilizados como agentes antiproliferativos.

Country Status (18)

Country Link
EP (2) EP0681584B1 (es)
JP (1) JPH08505877A (es)
KR (1) KR100308526B1 (es)
CN (1) CN1046285C (es)
AT (1) ATE201877T1 (es)
AU (1) AU685081B2 (es)
CA (1) CA2154668C (es)
DE (1) DE69427394T2 (es)
DK (1) DK0681584T3 (es)
ES (1) ES2159551T3 (es)
FI (1) FI953618A7 (es)
GR (1) GR3036506T3 (es)
NO (1) NO305989B1 (es)
NZ (1) NZ261497A (es)
PT (1) PT681584E (es)
RU (1) RU2127275C1 (es)
SG (1) SG49234A1 (es)
WO (1) WO1994017076A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW264475B (es) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
US5831100A (en) * 1995-06-07 1998-11-03 Agouron Pharmaceuticals, Inc. Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
US7250464B2 (en) 2000-02-18 2007-07-31 Rohm And Haas Company Distributed paint manufacturing system
WO2002014295A1 (fr) * 2000-08-16 2002-02-21 Elena Alexandrovna Izakson Derives de thiazines de la formule generale (1) manifestant une action antibacterienne et antivirale
US20040043959A1 (en) * 2002-03-04 2004-03-04 Bloom Laura A. Combination therapies for treating methylthioadenosine phosphorylase deficient cells
CN115231633B (zh) * 2022-06-27 2023-09-08 广东邦普循环科技有限公司 一种废蓄电池电解液收集处理装置及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives
EP0438261A3 (en) * 1990-01-16 1992-02-26 Takeda Chemical Industries, Ltd. Condensed heterocyclic glutamic acid derivatives, their production and use

Also Published As

Publication number Publication date
NZ261497A (en) 1997-06-24
DE69427394D1 (de) 2001-07-12
PT681584E (pt) 2001-09-28
SG49234A1 (en) 1998-05-18
JPH08505877A (ja) 1996-06-25
FI953618L (fi) 1995-07-28
CN1046285C (zh) 1999-11-10
NO305989B1 (no) 1999-08-30
CA2154668A1 (en) 1994-08-04
EP1094066A2 (en) 2001-04-25
FI953618A0 (fi) 1995-07-28
RU2127275C1 (ru) 1999-03-10
KR100308526B1 (ko) 2001-11-30
NO952996L (no) 1995-09-28
ATE201877T1 (de) 2001-06-15
WO1994017076A1 (en) 1994-08-04
NO952996D0 (no) 1995-07-28
DK0681584T3 (da) 2001-08-27
AU685081B2 (en) 1998-01-15
HK1014715A1 (en) 1999-09-30
CA2154668C (en) 2004-12-07
EP0681584B1 (en) 2001-06-06
GR3036506T3 (en) 2001-11-30
AU6026594A (en) 1994-08-15
DE69427394T2 (de) 2001-09-20
FI953618A7 (fi) 1995-07-28
EP0681584A1 (en) 1995-11-15
EP1094066A3 (en) 2001-05-02
RU95117099A (ru) 1997-06-27
CN1117295A (zh) 1996-02-21

Similar Documents

Publication Publication Date Title
ES2043625T3 (es) Derivados de acido ariloxicarboxilico, su preparacion y empleo.
ES8502106A1 (es) Un procedimiento para la preparacion de derivados de diben- zopirano
ES2059408T3 (es) Un proceso para la preparacion de un compuesto.
BR0009411A (pt) Composto de anilina substituìda, e, processo para a preparação e uso de compostos
TR200000197T2 (tr) Yeni bileşimler
ES2196054T3 (es) Derivados de acido fenilacetico, procedimiento y productos intermedios para su obtencion y agentes que contienen los mismos.
EE9900217A (et) Sulfiinhappe derivaadid, nende valmistamine ja kasutamine
PT90805A (pt) Processo para a preparacao de 1-indolilalquil-4-(piridinil substituido)-piperazinas e de composicoes farmaceuticas que as contem
YU56995A (sh) Soli derivata indola
DK57281A (da) Fremgangsmaade til fremstilling af substituerede imidazolderivater eller syreadditionssalte deraf
ES2130312T3 (es) Nuevos derivados de tetrazina con actividad acaricida.
ES2037665T3 (es) Procedimiento para la preparacion de compuestos heterociclicos que contienen n.
TR200002380T2 (tr) Yeni triazolo (4,5-d) pirimidin bileşikleri
ES2105362T3 (es) Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos.
ES2115220T3 (es) Nuevo uso de compuestos bis-heterociclicos como agentes antiinflamatorios y composiciones farmaceuticas de los mismos.
ES2096973T3 (es) Fosfazenos que contienen radicales organicos de silicio, proceso para su preparacion, y su empleo.
ES2159551T3 (es) Derivados de acido glutamico heterociclico condensado utilizados como agentes antiproliferativos.
IL111966A0 (en) 4-Benzoylisoxazole derivatives, their preparation and herbicidal compositions containing them
YU5893A (sh) Sulfonilkarbamid i postupak za njegovo dobijanje
DK121383D0 (da) Fremgangsmade til fremstilling af 8-substituerede pyrrolizidinderivater
ES2183492T3 (es) Nuevos derivados de nitrono,su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES556351A0 (es) Un procedimiento para preparar derivados de pirrolidona
ES8700242A1 (es) Un procedimiento para preparar un derivado de dihidropirida-zinona
ES8705421A1 (es) Un procedimiento para la preparacion de 4-amino-2-fenil-quinolinas
SE9802574D0 (sv) Novel compounds

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 681584

Country of ref document: ES