ES2158858T3 - Dializador, membrana y proceso de rectificacion. - Google Patents

Dializador, membrana y proceso de rectificacion.

Info

Publication number
ES2158858T3
ES2158858T3 ES93903007T ES93903007T ES2158858T3 ES 2158858 T3 ES2158858 T3 ES 2158858T3 ES 93903007 T ES93903007 T ES 93903007T ES 93903007 T ES93903007 T ES 93903007T ES 2158858 T3 ES2158858 T3 ES 2158858T3
Authority
ES
Spain
Prior art keywords
membranes
solvent
dialysis
membrane
porosity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93903007T
Other languages
English (en)
Inventor
Norma J Ofsthun
Lee W Henderson
Richard I Brown
Robin G Pauley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of ES2158858T3 publication Critical patent/ES2158858T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)

Abstract

LA INVENCION SE REFIERE A MEMBRANAS CON UN DOBLE REVESTIMIENTO UTILES COMO MEMBRANAS DE UNA DIRECCION O DE RECTIFICACION QUE REDUCEN EL QUE LAS MOLECULAS DE SOLUTOS SE VUELVAN A FILTRAR EN UNA DIALISIS Y QUE MEJORAR EL SUMINISTRO DE SUSTANCIAS NUTRITIVAS Y LA RECUPERACION DEL PRODUCTO EN LOS BIORREACTORES DE MEMBRANA. LAS MEMBRANAS SON MATERIALES POLIMERICOS CON UN DOBLE REVESTIMIENTO A MODO, PREFERENTEMENTE, DE FIBRAS HUECAS. LAS MEMBRANAS TIENEN REVESTIMIENTOS DE POLIMEROS EN LAS CARAS OPUESTAS CON UNAS CARACTERISTICAS DE POROSIDAD O DE LOS COEFICIENTES DE CRIBADO DIFERENTES. LAS MEMBRANAS SE FORMAN A BASE DE EXTRUIR UN POLIMERO DISUELTO EN UN SOLVENTE AL TIEMPO QUE POR LO MENOS UNA SUPERFICIE SE PONEN EN CONTACTO CON UN NO SOLVENTE MISCIBLE CON EL SOLVENTE. LA OTRA SUPERFICIE SE PONE EN CONTACTO CON UN NO SOLVENTE. LOS DOS NO SOLVENTES SON BIEN DIFERENTES ENTRE SI O BIEN UNO DE LOS NO SOLVENTES CONTIENE UN ADITIVO SOLUBLE QUE CAMBIA LA POROSIDAD DEL REVESTIMIENTO FORMADO EN EL POLIMERO EXTRUIDO DISUELTO. SE PUEDEN FORMAR DISPOSITIVO DE DIALISIS MEJORADOS SI SE UTILIZAN, COMO ELEMENTO DE DIALISIS, MANOJOS DE LAS MEMBRANAS DE FIBRAS HUECAS QUE TENGAN PROPIEDADES RECTIFICADORAS. SE PUEDEN FORMAR BIORREACTORES MEJORADOS SI SE UTILIZAN MANOJOS DE MEMBRANAS DE FIBRAS HUECAS COMO RECIPIENTE DE CULTIVO QUE TENGA PROPIEDADES RECTIFICADORAS.
ES93903007T 1992-01-10 1993-01-08 Dializador, membrana y proceso de rectificacion. Expired - Lifetime ES2158858T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/818,851 US5240614A (en) 1992-01-10 1992-01-10 Process for removing unwanted materials from fluids and for producing biological products

Publications (1)

Publication Number Publication Date
ES2158858T3 true ES2158858T3 (es) 2001-09-16

Family

ID=25226599

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93903007T Expired - Lifetime ES2158858T3 (es) 1992-01-10 1993-01-08 Dializador, membrana y proceso de rectificacion.

Country Status (11)

Country Link
US (1) US5240614A (es)
EP (1) EP0576659B1 (es)
JP (1) JP3197900B2 (es)
KR (1) KR100254664B1 (es)
CN (1) CN1031622C (es)
AT (1) ATE201230T1 (es)
CA (1) CA2104969A1 (es)
DE (1) DE69330221T2 (es)
ES (1) ES2158858T3 (es)
TW (1) TW265269B (es)
WO (1) WO1993014186A1 (es)

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KR960011587B1 (ko) * 1991-05-21 1996-08-24 브라운 유니버시티 리서치 파운데이션 중공섬유 제조장치와 중공섬유
US5527467A (en) * 1992-01-10 1996-06-18 Baxter International Inc. Rectifying dialyzer, bioreactor and membrane
US5480552A (en) * 1992-01-10 1996-01-02 Baxter International Inc. Method for concentrating a solute with an oscillating filtration device
DE69419095T2 (de) * 1993-03-09 2000-02-03 Baxter International Inc., Deerfield Rektifikationsdialysator, membran und bioreaktor
DE69634352T2 (de) * 1995-06-30 2006-01-12 Toray Industries, Inc. Methode zur Herstellung einer teildurchlässigen Hohlfasermembran aus Polysulfon
US5714072A (en) * 1995-11-06 1998-02-03 Hoechst Celanese Corporation Method for solvent extraction using a dual-skinned asymmetric microporous membrane
JP4451931B2 (ja) * 1996-11-12 2010-04-14 ホアットマン，インコーポレーテッド 親水性のポリマー状の相転換メンブレン
US5955353A (en) * 1997-05-22 1999-09-21 Excorp Medical, Inc. Hollow fiber bioreactor with an extrafilament flow plug
US6099730A (en) * 1997-11-14 2000-08-08 Massachusetts Institute Of Technology Apparatus for treating whole blood comprising concentric cylinders defining an annulus therebetween
US7211037B2 (en) 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7186230B2 (en) * 2002-03-04 2007-03-06 Therakos, Inc Method and apparatus for the continuous separation of biological fluids into components
US7153286B2 (en) 2002-05-24 2006-12-26 Baxter International Inc. Automated dialysis system
US7175606B2 (en) 2002-05-24 2007-02-13 Baxter International Inc. Disposable medical fluid unit having rigid frame
US7238164B2 (en) 2002-07-19 2007-07-03 Baxter International Inc. Systems, methods and apparatuses for pumping cassette-based therapies
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US7476209B2 (en) 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
US20090078641A1 (en) * 2006-03-09 2009-03-26 Toyo Boseki Kabushiki Kaisha Hollow fiber membrane with excellent performance stability and blood purifier and method for producing hollow fiber membrane
US8062513B2 (en) 2008-07-09 2011-11-22 Baxter International Inc. Dialysis system and machine having therapy prescription recall
US9514283B2 (en) 2008-07-09 2016-12-06 Baxter International Inc. Dialysis system having inventory management including online dextrose mixing
US10487148B2 (en) 2010-01-28 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated impairments
WO2017120461A1 (en) 2016-01-08 2017-07-13 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
WO2015088915A1 (en) 2013-12-09 2015-06-18 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
EP3122866B1 (en) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passive replacement of media
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
CN116687969A (zh) 2015-05-18 2023-09-05 小利兰·斯坦福大学托管委员会 用于治疗衰老相关的损伤的方法和组合物
SI3307296T1 (sl) 2015-06-15 2022-04-29 The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel TIMP2 za uporabo pri zdravljenju s starostjo povezanih stanj
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN105664730B (zh) * 2016-04-14 2017-12-05 北京航空航天大学 一种可调控液体单向透过范围的复合膜及其制备方法
JP7034949B2 (ja) 2016-05-25 2022-03-14 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN109803748A (zh) * 2016-09-30 2019-05-24 东丽株式会社 培养血小板浓缩组件及使用其的血小板制剂的制造方法
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion

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FR2380052A1 (fr) * 1977-02-11 1978-09-08 Akzo Nv Membrane de dialyse pour l'hemodialyse
JPS54145379A (en) * 1978-05-02 1979-11-13 Asahi Chem Ind Co Ltd Aromatic polysulfone hollow fiber semipermeable membrane
DE2823985C2 (de) * 1978-06-01 1986-01-02 Akzo Gmbh, 5600 Wuppertal Dialysemembran
DE3270865D1 (en) * 1981-08-22 1986-06-05 Asahi Chemical Ind Aromatic polysulfone resin hollow yarn membrane and process for manufacturing same
JPS58132111A (ja) * 1982-01-29 1983-08-06 Asahi Chem Ind Co Ltd ポリスルホン中空糸
JPS60246812A (ja) * 1984-05-18 1985-12-06 Daicel Chem Ind Ltd ポリスルホン系樹脂製中空糸
EP0183757B1 (fr) * 1984-06-13 1991-10-30 Lyonnaise Des Eaux - Dumez Procede de fabrication de fibres creuses et leurs applications notamment dans le domaine des separations par membranes
WO1986002379A1 (en) * 1984-10-09 1986-04-24 Endotronics, Inc. Hollow fiber culture device for improved nutrient perfusion and product concentration and method of operation
JPS61164602A (ja) * 1985-01-17 1986-07-25 Daicel Chem Ind Ltd ポリスルホン系樹脂製中空糸膜
JPS621404A (ja) * 1985-06-27 1987-01-07 Mitsubishi Rayon Co Ltd 多層複合中空繊維状膜及びその製造法
JP2542572B2 (ja) * 1985-11-15 1996-10-09 日機装 株式会社 中空繊維
JPS62241528A (ja) * 1986-04-10 1987-10-22 Nisso Eng Kk トリクロロエチレン含有排ガスの処理方法
DE3851572T2 (de) * 1987-06-12 1995-05-24 Kuraray Co Polysulfon-Hohlfasermembran und Verfahren zu ihrer Herstellung.
US5015585A (en) * 1988-02-23 1991-05-14 Robinson James R Method and apparatus for culturing and diffusively oxygenating cells on isotropic membranes
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Also Published As

Publication number Publication date
CA2104969A1 (en) 1993-07-11
CN1031622C (zh) 1996-04-24
EP0576659B1 (en) 2001-05-16
US5240614A (en) 1993-08-31
TW265269B (es) 1995-12-11
DE69330221T2 (de) 2002-04-18
JPH06505640A (ja) 1994-06-30
EP0576659A1 (en) 1994-01-05
WO1993014186A1 (en) 1993-07-22
ATE201230T1 (de) 2001-06-15
KR100254664B1 (ko) 2000-05-01
JP3197900B2 (ja) 2001-08-13
CN1078410A (zh) 1993-11-17
DE69330221D1 (de) 2001-06-21

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