ES2156899T3 - Nuevo procedimiento de preparacion de ergotioneina. - Google Patents
Nuevo procedimiento de preparacion de ergotioneina.Info
- Publication number
- ES2156899T3 ES2156899T3 ES94920514T ES94920514T ES2156899T3 ES 2156899 T3 ES2156899 T3 ES 2156899T3 ES 94920514 T ES94920514 T ES 94920514T ES 94920514 T ES94920514 T ES 94920514T ES 2156899 T3 ES2156899 T3 ES 2156899T3
- Authority
- ES
- Spain
- Prior art keywords
- ergotioneine
- new
- substitute
- preparation procedure
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA INVENCION SE REFIERE A UN NUEVO PROCESO DE PREPARACION DE ERGOTIONEINA. EL PROCESO DE SINTESIS QUIMICA DE LAS DIFERENTES FORMAS OPTICAS DE LA ERGOTIONEINA SE CARACTERIZA EN QUE COMPRENDE ESENCIALMENTE LAS ETAPAS QUE CONSISTEN EN PREPARAR O UTILIZAR UNA SAL DE ESTER DE HISTIDINANALFAR-NALFA-DIMETILADA, SI ES NECESARIO OPTICAMENTE ACTIVO; EN TRATAR ESTE COMPUESTO, POR UN HALOGENOTIONOFORMIATO DE ALKILO, DE ALQUENILO O DE ARILO, EN PRESENCIA DE UNA BASE; Y TRAS LA PROTECCION DEL SUSTITUYENTE AZUFRADO DEL COMPUESTO OBTENIDO, TRANSFORMAR ESTE ULTIMO EN UN COMPUESTO DE TIPO TRIMETILAMONIO, Y EN LIBERAR LA ERGOTIONEINA DESEADA POR SAPONIFICACION O HIDROLISIS ACIDA, SEGUN EL CASO. ESTE PROCESO PROCURA UN MEJOR RENDIMIENTO Y ASEGURA UNA EXCELENTE PUREZA OPTICA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9307839A FR2707086A1 (fr) | 1993-06-28 | 1993-06-28 | Procédé de préparation de l'ergothionéine. |
FR9315457A FR2707087B1 (fr) | 1993-06-28 | 1993-12-22 | Nouveau procédé de préparation de l'ergothionéine. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2156899T3 true ES2156899T3 (es) | 2001-08-01 |
Family
ID=26230438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94920514T Expired - Lifetime ES2156899T3 (es) | 1993-06-28 | 1994-06-27 | Nuevo procedimiento de preparacion de ergotioneina. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5438151A (es) |
EP (1) | EP0656890B1 (es) |
JP (2) | JP3840616B2 (es) |
AU (1) | AU688337B2 (es) |
CA (1) | CA2143419C (es) |
DE (1) | DE69426520T2 (es) |
ES (1) | ES2156899T3 (es) |
FR (1) | FR2707087B1 (es) |
WO (1) | WO1995000494A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2707087B1 (fr) * | 1993-06-28 | 1995-10-13 | Bioxytech | Nouveau procédé de préparation de l'ergothionéine. |
US6103746A (en) * | 1997-02-20 | 2000-08-15 | Oxis International, Inc. | Methods and compositions for the protection of mitochondria |
US6479533B1 (en) | 1997-02-20 | 2002-11-12 | Applied Genetics Incorporated Dermatics | Methods and compositions for the protection of mitochondria |
EP1051165A2 (en) | 1998-01-26 | 2000-11-15 | Mitokor | Mitochondria protecting agents for treating mitochondria associated diseases |
PT1917966E (pt) * | 1998-02-13 | 2010-03-17 | Nutramax Lab Inc | Agentes e métodos para protecção, tratamento e reparação de tecido conjuntivo |
FR2810548A1 (fr) * | 2000-06-26 | 2001-12-28 | Oreal | Utilisation d'ergothioneine et/ou de ses derives comme agent anti-glycation |
US20050042233A1 (en) * | 2003-08-21 | 2005-02-24 | Christopher Marrs | Stabilized compositions containing an oxygen-labile active agent and a fungal extract |
US20050042306A1 (en) * | 2003-08-21 | 2005-02-24 | Christopher Marrs | Stabilized compositions containing an oxygen-labile active agent |
FR2910808B1 (fr) * | 2006-12-29 | 2009-04-10 | Lvmh Rech | Utilisation en cosmetique de la l-2-thiohistidine ou d'un de ses derives comme agent depigmentant. |
EP2134198A4 (en) * | 2007-03-07 | 2012-08-29 | Robert B Beelman | USE OF ERGOTHIONEIN AS A PRESERVATIVE IN FOOD AND BEVERAGES |
US7767826B2 (en) * | 2007-10-05 | 2010-08-03 | Pharmatech International, Inc. | Process for the synthesis of L-(+)-ergothioneine |
US8933245B2 (en) | 2009-01-30 | 2015-01-13 | Elc Management Llc | Preservation of ergothioneine |
US8410156B2 (en) * | 2009-01-30 | 2013-04-02 | Elc Management, Llc | Preservation of ergothioneine |
FR2950889B1 (fr) * | 2009-10-06 | 2011-11-18 | Tetrahedron | Procede de synthese de l'ergothioneine et analogues |
FR2950890B1 (fr) | 2009-10-06 | 2011-12-30 | Tetrahedron | Procede de synthese de la 2-thiohistidine et analogues |
EP3137611B1 (en) | 2014-04-29 | 2021-02-24 | Conagen Inc. | Microbial ergothioneine biosynthesis |
US11390897B2 (en) | 2014-12-22 | 2022-07-19 | National University Corporation Okayama University | Method for producing ergothioneine |
EP3268354B1 (en) | 2015-03-13 | 2020-05-06 | Mironova Innovations, LLC | Nalpha, nalpha, nalpha-trialkyl histidine derivatives useful for the preparation of ergothioneine compounds |
JP6948453B2 (ja) | 2018-02-23 | 2021-10-13 | 長瀬産業株式会社 | エルゴチオネインの製造方法 |
CA3145979A1 (en) | 2019-07-10 | 2021-01-14 | Kureha Corporation | Plant growth regulator and method for promoting plant growth |
JPWO2021132655A1 (es) | 2019-12-27 | 2021-07-01 | ||
WO2022185872A1 (ja) | 2021-03-01 | 2022-09-09 | 長瀬産業株式会社 | エルゴチオネインの製造方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2707087B1 (fr) * | 1993-06-28 | 1995-10-13 | Bioxytech | Nouveau procédé de préparation de l'ergothionéine. |
-
1993
- 1993-12-22 FR FR9315457A patent/FR2707087B1/fr not_active Expired - Fee Related
-
1994
- 1994-02-08 US US08/194,457 patent/US5438151A/en not_active Expired - Lifetime
- 1994-06-27 WO PCT/FR1994/000769 patent/WO1995000494A1/fr active IP Right Grant
- 1994-06-27 EP EP94920514A patent/EP0656890B1/fr not_active Expired - Lifetime
- 1994-06-27 CA CA002143419A patent/CA2143419C/en not_active Expired - Fee Related
- 1994-06-27 ES ES94920514T patent/ES2156899T3/es not_active Expired - Lifetime
- 1994-06-27 AU AU71276/94A patent/AU688337B2/en not_active Ceased
- 1994-06-27 DE DE69426520T patent/DE69426520T2/de not_active Expired - Fee Related
- 1994-06-27 JP JP50252895A patent/JP3840616B2/ja not_active Expired - Fee Related
-
2006
- 2006-01-11 JP JP2006004030A patent/JP2006160748A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2143419A1 (en) | 1995-01-05 |
AU7127694A (en) | 1995-01-17 |
CA2143419C (en) | 2006-01-24 |
DE69426520T2 (de) | 2001-07-12 |
JP3840616B2 (ja) | 2006-11-01 |
EP0656890B1 (fr) | 2001-01-03 |
DE69426520D1 (de) | 2001-02-08 |
EP0656890A1 (fr) | 1995-06-14 |
WO1995000494A1 (fr) | 1995-01-05 |
JP2006160748A (ja) | 2006-06-22 |
FR2707087B1 (fr) | 1995-10-13 |
US5438151A (en) | 1995-08-01 |
JPH08501575A (ja) | 1996-02-20 |
FR2707087A1 (fr) | 1995-01-06 |
AU688337B2 (en) | 1998-03-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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